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Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ]
收藏  |  浏览/下载:138/0  |  提交时间:2019/06/28
Recent advancements in mesoporous silica nanoparticles towards therapeutic applications for cancer 期刊论文
2019, 卷号: 89, 页码: 1-13
作者:  Li, Tingting[1,2,3];  Shi, Sixiang[2];  Goel, Shreya[4];  Shen, Xue[1];  Xie, Xiaoxue[1]
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/06
Fabrication, Characterization, and Application of Large-Scale Uniformly Hybrid Nanoparticle-Enhanced Raman Spectroscopy Substrates 期刊论文
MICROMACHINES, 2019, 卷号: 10, 期号: 5
作者:  Qi, Qi[1];  Liu, Chunhui[2];  Liu, Lintao[3];  Meng, Qingyi[4];  Wei, Shuhua[5]
收藏  |  浏览/下载:15/0  |  提交时间:2020/01/02
Etiology of community-acquired pneumonia in 1500 hospitalized children 期刊论文
Journal of medical virology, 2018, 卷号: 90, 页码: 421-428
作者:  Oumei Hao[1];  Xuefeng Wang[2];  Jianping Liu[3];  Kunling Shen[4];  Rong Ma[5]
收藏  |  浏览/下载:10/0  |  提交时间:2019/04/24
Influence of ultrasonic vibration on percussion drilling performance for millisecond pulsed Nd:YAG laser 期刊论文
OPTICS AND LASER TECHNOLOGY, 2018, 卷号: 104, 页码: 133-139
作者:  Wang, Houxiao[1];  Zhu, Sukai[2];  Xu, Guoxiang[3];  Zhou, Wei[4];  Li, Lin[5]
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/24
Structure characterization of a novel polysaccharide from Hericium erinaceus fruiting bodies and its immunomodulatory activities 期刊论文
2018, 卷号: 9, 期号: 1, 页码: 294
作者:  Wu, Fangfang[1];  Zhou, Chunhui[2];  Zhou, Dandan[2];  Ou, Shiyi[3];  Zhang, Xiaoai[4]
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/06
A targeting theranostics nanomedicine as an alternative approach for hyperthermia perfusionSCI原文链接 期刊论文
2018, 卷号: 183, 页码: 268-279
作者:  Sun, Tao[1];  Zhang, Guangping[2,3];  Wang, Qingbing[4];  Chen, Qinjun[1];  Chen, Xinli[1]
收藏  |  浏览/下载:18/0  |  提交时间:2019/12/31
Oral Immunization with Nontoxigenic Clostridium difficile Strains Expressing Chimeric Fragments of TcdA and TcdB Elicits Protective Immunity against C. difficile Infection in Both Mice and Hamsters 期刊论文
2018, 卷号: 86, 期号: 11
作者:  Wang, Yuanguo[1];  Wang, Shaohui[1];  Bouillaut, Laurent[2];  Li, Chunhui[1];  Duan, Zhibian[1,3]
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/26
Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4904-4916
作者:  Xiamuxi, H (Xiamuxi, Hainimu);  Wang, Z (Wang, Zhen);  Li, JF (Li, Jianfeng);  Wang, Y (Wang, Yu);  Wu, CH (Wu, Chunhui)
收藏  |  浏览/下载:112/0  |  提交时间:2017/10/31
5-Hydroxycyclopenicillone, a New beta-Amyloid Fibrillization Inhibitor from a Sponge-Derived Fungus Trichoderma sp HPQJ-34 期刊论文
2017, 卷号: 15, 期号: [db:dc_citation_issue]
作者:  Fang, Fang[1];  Zhao, Jiaying[1];  Ding, Lijian[1];  Huang, Chunhui[1];  Naman, C. Benjamin[2,3]
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/03


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