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科研机构
中南大学 [2]
湖南农业大学 [1]
湖南中医药大学 [1]
昆明动物研究所 [1]
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期刊论文 [5]
发表日期
2018 [1]
2016 [2]
2014 [1]
2011 [1]
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Selective Closed-State Nav1.7 Blocker JZTX-34 Exhibits Analgesic Effects against Pain
期刊论文
Toxins, 2018, 卷号: 10, 期号: 2, 页码: 64
作者:
Mingqiang Rong
;
Juan Huang
;
Ren Lai
;
Xiongzhi Zeng
;
Bo Chen
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2018/09/29
Peptide Toxin
Sodium Channels
Nav1.7
Pain
Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels
期刊论文
Toxicon, 2016, 卷号: 111, 期号: Volume 111, 页码: 13-21
作者:
Tao, Huai*
;
Chen, Xia
;
Lu, Min
;
Wu, Yuanyuan
;
Deng, Meichun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
Jingzhaotoxin-I
Voltage-gated sodium channels
Inactivation
Mutation
JZTX
Jingzhaotoxin
VGSCs
voltage-gated sodium channels
TTX
tetrodotoxin
ICK
inhibitor cystine knot
RP-HPLC
reverse-phase high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
IC50
half-maximal inhibitory concentration
WT
wide type
Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels
期刊论文
Toxicon, 2016, 卷号: 111, 期号: Volume 111, 页码: 13-21
作者:
Tao, Huai*(陶怀)
;
Chen, Xia
;
Lu, Min
;
Wu, Yuanyuan
;
Deng, Meichun
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Jingzhaotoxin-I
Voltage-gated sodium channels
Inactivation
Mutation
JZTX
Jingzhaotoxin
VGSCs
voltage-gated sodium channels
TTX
tetrodotoxin
ICK
inhibitor cystine knot
RP-HPLC
reverse-phase high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
IC50
half-maximal inhibitory concentration
WT
wide type
Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena
期刊论文
Neuropharmacology, 2014, 卷号: 79, 页码: 657-667
作者:
Deng, Meichun*
;
Luo, Xuan
;
Xiao, Yucheng
;
Sun, Zhenghua
;
Jiang, Liping
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/03
HWTX-XVI
Tarantula toxin
N-type calcium channels
Dorsal root ganglia
Rat vas deferens
Pain model
Analgesic action
HWTX
Huwentoxin
ICK
inhibitor cystine knot
Cav channel
voltage-gated calcium channel
Nav channel
voltage-gated sodium channel
DRG
dorsal root ganglion
TTX
tetrodotoxin
TTX-R
TTX-resistant
TTX-S
TTX-sensitive
IC50
median inhibitory concentration
Kv channel
voltage-gated potassium channel
HPLC
high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
Molecular basis of the tarantula toxin jingzhaotoxin-III (beta-TRTX-Cj1 alpha) interacting with voltage sensors in sodium channel subtype Nav1.5
期刊论文
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, 卷号: 25, 期号: 9, 页码: 3177-3185
作者:
Rong, Mingqiang
;
Chen, Jinjun
;
Tao, Huai
;
Wu, Yuanyuan
;
Jiang, Peng
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/23
spider toxin
mutation
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