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浏览/检索结果: 共14条，第1-10条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990 作者:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ] 收藏  |  浏览/下载：141/0  |  提交时间：2019/06/28 Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening 期刊论文 Bioorganic chemistry, 2019, 卷号: 86, 页码: 494-500 作者:  Zhang Dan[1];  Han Jie[2];  Lu Wenchao[3];  Lian Fulin[4];  Wang Jun[5] 收藏  |  浏览/下载：36/0  |  提交时间：2019/04/22 BPTF inhibitor  Bromodomain  Lysine acetylation  Virtual screening   Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening 期刊论文 RSC ADVANCES, 2019, 卷号: 9, 页码: 4917-4924 作者:  Tao, Hongru[1];  Wang, Jun[2];  Lu, Wenchao[3];  Zhang, Rukang[4];  Xie, Yiqian[5] 收藏  |  浏览/下载：29/0  |  提交时间：2019/04/22 Effects of dietary tryptophan levels on antioxidant status and immunity for juvenile blunt snout bream (Megalobrama amblycephala) involved in Nrf2 and TOR signaling pathway 期刊论文 FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 93, 页码: 474-483 作者:  Ji, Ke[1];  Liang, Hualiang[2];  Ren, Mingchun[3];  Ge, Xianping[4];  Li, Bo[5] 收藏  |  浏览/下载：9/0  |  提交时间：2020/01/02 Blunt snout bream (Megalobrama amblycephala)  Tryptophan  Nrf2 signaling pathway  TOR signaling pathway  NF-kappa B signaling pathway   Discovery of 1,8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 740-751 作者:  Xiong, Huan[1];  Han, Jie[2];  Wang, Jun[3];  Lu, Wenchao[4];  Wang, Chen[5] 收藏  |  浏览/下载：7/0  |  提交时间：2019/04/24 Epigenetics  Histone acetyltransferase  GCN5  High throughput screening  1  8-Acridinedione derivative   Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors 期刊论文 Bioorganic & medicinal chemistry, 2018, 卷号: 26, 页码: 5397-5407 作者:  Lu Wenchao[1];  Xiong Huan[2];  Chen Yu[3];  Wang Chen[4];  Zhang Hao[5] 收藏  |  浏览/下载：14/0  |  提交时间：2019/04/22 Drug discovery  Epigenetics  Histone acetyltransferase  P300/CBP   The age variation of HER2 immunohistochemistry positive rate in gastric cancer 会议论文 MODERN PATHOLOGY, 2018-03-01 作者:  Xi, Yangfeng[1];  Xu, Chen[2];  Liu, Yiqiang[3];  Yan, Xiaochu[4];  Huang, Chuansheng[5] 收藏  |  浏览/下载：57/0  |  提交时间：2019/12/24 The age variation of HER2 immunohistochemistry positive rate in gastric cancer 期刊论文 MODERN PATHOLOGY, 2018, 卷号: 31, 页码: 311-312 作者:  Xi, Yangfeng[1];  Xu, Chen[2];  Liu, Yiqiang[3];  Yan, Xiaochu[4];  Huang, Chuansheng[5] 收藏  |  浏览/下载：48/0  |  提交时间：2019/12/24 Effects of dietary lipid sources on growth performance, fatty acid composition and hepatic lipid metabolism of juvenile blunt snout bream, Megalobrama amblycephala 期刊论文 AQUACULTURE NUTRITION, 2018, 卷号: 24, 期号: 6, 页码: 1652-1663 作者:  Zhang, Wuxiao[1];  Sun, Shengming[2];  Ge, Xianping[3];  Zhu, Jian[4];  Miao, Linghong[5] 收藏  |  浏览/下载：8/0  |  提交时间：2020/01/02 dietary lipids  linseed oil  lipid metabolism  Megalobrama amblycephala   Acute effects of ammonia exposure on the plasma and haematological parameters and histological structure of the juvenile blunt snout bream, Megalobrama amblycephala, and post-exposure recovery 期刊论文 AQUACULTURE RESEARCH, 2018, 卷号: 49, 期号: 2, 页码: 1008-1019 作者:  Zhang, Wuxiao[1];  Sun, Shengming[2];  Ge, Xianping[3];  Xia, Silei[4];  Zhu, Jian[5] 收藏  |  浏览/下载：3/0  |  提交时间：2020/01/02 ammonia  histological structure  Megalobrama amblycephala  plasma