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Identification of potential drug-targets by combining evolutionary information extracted from frequency profiles and molecular topological structures
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 卷号: 96, 期号: 2, 页码: 758-767
作者:
Wang, L (Wang, Lei)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
;
Yan, X (Yan, Xin)[ 3 ]
;
Zhang, W (Zhang, Wei)[ 1 ]
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/11/04
drug-target interaction
rotation forest
two-dimensional principal component analysis
Incorporating chemical sub-structures and protein evolutionary information for inferring drug-target interactions
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 1-11
作者:
Wang, L (Wang, Lei)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
;
Yan, X (Yan, Xin)[ 3 ]
;
Zhang, W (Zhang, Wei)[ 1 ]
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/09
GANCDA: a novel method for predicting circRNA-disease associations based on deep generative adversarial network
期刊论文
INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS, 2020, 卷号: 23, 期号: 3, 页码: 265-283
作者:
Yan, X (Yan, Xin)[ 1 ]
;
Wang, L (Wang, Lei)[ 2,3 ]
;
You, ZH (You, Zhu-Hong)[ 3 ]
;
Li, LP (Li, Li-Ping)[ 3 ]
;
Zheng, K (Zheng, Kai)[ 4 ]
收藏
  |  
浏览/下载:261/0
  |  
提交时间:2020/12/11
circular RNA
diseases
CircRNA-disease association
generative adversarial network
logistic model tree
NLPEI: A Novel Self-Interacting Protein Prediction Model Based on Natural Language Processing and Evolutionary Information
期刊论文
EVOLUTIONARY BIOINFORMATICS, 2020, 卷号: 16, 期号: 12, 页码: 1-12
作者:
Jia, LN (Jia, Li-Na)[ 1 ]
;
Yan, X (Yan, Xin)[ 2,3 ]
;
You, ZH (You, Zhu-Hong)[ 4 ]
;
Zhou, X (Zhou, Xi)[ 4 ]
;
Li, LP (Li, Li-Ping)[ 4 ]
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/03/19
Self-interacting protein
natural language processing
evolutionary information
stacked auto-encoder
Age Is Important for the Early-Stage Detection of Breast Cancer on Both Transcriptomic and Methylomic Biomarkers
期刊论文
FRONTIERS IN GENETICS, 2019, 卷号: 10, 期号: 3, 页码: 1-13
作者:
Feng, X (Feng, Xin)[ 1,2 ]
;
Li, JL (Li, Jialiang)[ 2,3 ]
;
Li, H (Li, Han)[ 2,3 ]
;
Chen, H (Chen, Hang)[ 1,2 ]
;
Li, F (Li, Fei)[ 2,3 ]
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2019/04/18
age
feature selection
TriVote
BRCA
classification
transcriptome
methylome
Ultrasmall Abundant Metal-Based Clusters as Oxygen-Evolving Catalysts
期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019, 卷号: 141, 期号: 1, 页码: 232-239
作者:
Han, XB (Han, Xin-Bao)[ 1,2 ]
;
Tang, XY (Tang, Xing-Yan)[ 1,2 ]
;
Lin, Y (Lin, Yue)[ 3 ]
;
Gracia-Espino, E (Gracia-Espino, Eduardo)[ 5 ]
;
Liu, SG (Liu, San-Gui)[ 1,2 ]
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  |  
浏览/下载:114/0
  |  
提交时间:2019/03/05
Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice
期刊论文
Phytotherapy research : PTR, 2019, 卷号: 33, 页码: 117-129
作者:
Xu Ying[1]
;
Li Xin[2]
;
Chen Ting[3]
;
Qu Ya-Kun[4]
;
Zheng Hong-Xia[5]
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/04/22
780 reproductive target tissue
ERα
ERβ
estrogen receptor antagonist ICI182
estrogenic effect
Mechanism of Regulation of Big-Conductance Ca2+-Activated K+ Channels by mTOR Complex 2 in Podocytes
期刊论文
Frontiers in physiology, 2019, 卷号: 10, 页码: 167
作者:
Wang Yinhang[1]
;
Tao Jie[2]
;
Wang Mengling[3]
;
Yang Licai[4]
;
Ning Fengling[5]
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/04/22
Akt
BK channels
PKCα
SGK1
mTORC2
podocyte
Inhibition of CTHRC-1 by its specific monoclonal antibody attenuates cervical cancer cell metastasis
期刊论文
Biomedicine & pharmacotherapy, 2019, 卷号: 110, 页码: 758-763
作者:
Cui Xiao-Xiao[1]
;
Ding Hong-Mei[2]
;
Gu Fei[3]
;
Lv Yuan-Yuan[4]
;
Xing Xin[5]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/04/22
CTHRC-1
Cervical cancer
Monoclonal antibody drug
CXCL6 Promotes Renal Interstitial Fibrosis in Diabetic Nephropathy by Activating JAK/STAT3 Signaling Pathway
期刊论文
Frontiers in pharmacology, 2019, 卷号: 10, 页码: 224
作者:
Sun Meng-Yao[1]
;
Wang Su-Juan[2]
;
Li Xiao-Qin[3]
;
Shen Yu-Li[4]
;
Lu Jian-Rao[5]
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/04/22
CXCL6
diabetics
fibrosis
kidney
pathway
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