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科研机构
西安交通大学 [4]
中南大学 [3]
复旦大学上海医学院 [3]
内容类型
期刊论文 [10]
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2019 [1]
2018 [2]
2017 [1]
2016 [1]
2015 [1]
2013 [1]
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Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance
期刊论文
JOURNAL OF CLINICAL INVESTIGATION, 2019, 卷号: 129, 期号: 6
作者:
Pan, Chaoyun
;
Jin, Lingtao
;
Wang, Xu
;
Li, Yuancheng
;
Chun, Jaemoo
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/05
MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation
期刊论文
CANCER CELL, 2018, 卷号: 34, 期号: 2
作者:
Jin, Lingtao
;
Chun, Jaemoo
;
Pan, Chaoyun
;
Li, Dan
;
Lin, Ruiting
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer
期刊论文
MOLECULAR CELL, 2018, 卷号: 69, 期号: 1
作者:
Jin, Lingtao
;
Chun, Jaemoo
;
Pan, Chaoyun
;
Kumar, Avi
;
Zhang, Guojing
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Overcoming Acquired Resistance to AZD9291, A Third-Generation EGFR Inhibitor, through Modulation of MEK/ERK-Dependent Bim and Mcl-1 Degradation
期刊论文
CLINICAL CANCER RESEARCH, 2017, 卷号: 23, 页码: 6567-6579
作者:
Shi, Puyu
;
Oh, You-Take
;
Deng, Liang
;
Zhang, Guojing
;
Qian, Guoqing
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/26
Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment
期刊论文
CANCER LETTERS, 2016, 卷号: 380, 期号: [db:dc_citation_issue], 页码: 494-504
作者:
Shi, Puyu
;
Oh, You Take
;
Zhang, Guojing
;
Yao, Weilong
;
Yue, Ping
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/02
Bim
EGFR
Resistance
AZD9291
Met
Erlotinib
Enhancing therapeutic efficacy of the MEK inhibitor, MEK162, by blocking autophagy or inhibiting PI3K/Akt signaling in human lung cancer cells
期刊论文
Cancer Letters, 2015, 卷号: 364, 期号: 1, 页码: 70-78
作者:
Yao, Weilong
;
Yue, Ping
;
Zhang, Guojing
;
Owonikoko, Taofeek K.
;
Khuri, Fadlo R.
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
MEK162
BKM120
Autophagy
Lung cancer
The PI3 kinase inhibitor NVP-BKM120 induces GSK3/FBXW7-dependent Mcl-1 degradation, contributing to induction of apoptosis and enhancement of TRAIL-induced apoptosis
期刊论文
CANCER LETTERS, 2013, 卷号: 338, 期号: [db:dc_citation_issue], 页码: 229-238
作者:
Ren, Hui
;
Zhao, Liqun
;
Li, Yikun
;
Yue, Ping
;
Deng, Xingming
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/10
PI3 kinase
Lung cancer
BKM120
Apoptosis
TRAIL
Elevated expression of eukaryotic translation initiation factor 4E is associated with proliferation, invasion and acquired resistance to erlotinib in lung cancer
期刊论文
Cancer Biology and Therapy, 2012, 卷号: 13, 期号: 5, 页码: 272-280
作者:
Li, Yikun
;
Fan, Songqing
;
Koo, Junghui
;
Yue, Ping
;
Chen, Zhuo
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Erlotinib
Invasion
Lung cancer
Proliferation
Resistance
eIF4E
c-Myc Suppression of DNA Double-strand Break Repair
期刊论文
Neoplasia (New York, N.Y.), 2012, 卷号: 14, 期号: 12, 页码: 1190-1202
作者:
Li, Zhaozhong
;
Owonikoko, Taofeek K.
;
Sun, Shi-Yong
;
Ramalingam, Suresh S.
;
Doetsch, Paul W.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
HR
homologous recombination
NHEJ
nonhomologous end-joining
DSB
DNA double-strand break
PFGE
pulsed-field gel electrophoresis
siRNA
small interfering RNA
RNAi
RNA interference
DOX
doxycycline
DNA-PKcs
DNA-dependent protein kinase catalytic subunit
The combination of RAD001 and NVP-BKM120 synergistically inhibits the growth of lung cancer in vitro and in vivo
期刊论文
CANCER LETTERS, 2012, 卷号: 325, 期号: [db:dc_citation_issue], 页码: 139-146
作者:
Ren, Hui
;
Chen, Mingwei
;
Yue, Ping
;
Tao, Hui
;
Owonikoko, Taofeek K.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/10
PI3 kinase
Lung cancer
BKM120
RAD001
mTOR
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