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科研机构
合肥物质科学研究院 [18]
安徽大学 [4]
遥感与数字地球研究所 [3]
山东大学 [3]
北京大学 [1]
中南大学 [1]
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期刊论文 [34]
会议论文 [3]
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2022 [3]
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2020 [5]
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2017 [5]
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浏览/检索结果:
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Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:
Liang, Xiaofei
;
Wang, Chun
;
Wang, Beilei
;
Liu, Juan
;
Qi, Shuang
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/12/23
CSF1R inhibitor
Kinase inhibitor
Macrophage polarization
PEG-Bottlebrush Stabilizer-Based Worm-like Nanocrystal Micelles with Long-Circulating and Controlled Release for Delivery of a BCR-ABL Inhibitor against Chronic Myeloid Leukemia (CML)
期刊论文
PHARMACEUTICS, 2022, 卷号: 14
作者:
Liang, Huamin
;
Zou, Fengming
;
Fu, Liyi
;
Liu, Qingwang
;
Wang, Beilei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/23
drug nanocrystal
stabilizer
micelle
BCR-ABL
chronic myeloid leukemia (CML)
Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2
期刊论文
LEUKEMIA, 2022
作者:
Yang, Jing
;
Weisberg, Ellen L.
;
Qi, Shuang
;
Ni, Wei
;
Mei, Husheng
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2022/02/14
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML)
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 897
作者:
Lu, Tingting
;
Cao, Jiangyan
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/04/26
BCR-ABL
ABL mutants
Chronic myeloid leukemia
Kinase inhibitor
Imatinib resistance
Nanocrystal-loaded liposome for targeted delivery of poorly water-soluble antitumor drugs with high drug loading and stability towards efficient cancer therapy
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 599
作者:
Liang, Huamin
;
Zou, Fengming
;
Liu, Qingwang
;
Wang, Beilei
;
Fu, Liyi
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/05/17
Liposome
Drug nanocrystal
Core-shell
Drug delivery
Tumor therapy
BCR-ABL
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214, 页码: 16
作者:
Xu, Biao
;
Wang, Zhi-Peng
;
Liu, Qingwang
;
Yang, Xiaohong
;
Li, Xuemin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/17
Pyruvate dehydrogenase kinase
Proliferation
Cancer metabolism
Structure-activity relationship
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214
作者:
Xu, Biao
;
Wang, Zhi-Peng
;
Liu, Qingwang
;
Yang, Xiaohong
;
Li, Xuemin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/04/26
Pyruvate dehydrogenase kinase
Proliferation
Cancer metabolism
Structure-activity relationship
Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia
期刊论文
HAEMATOLOGICA, 2021, 卷号: 106
作者:
Wang, Aoli
;
Hu, Chen
;
Chen, Cheng
;
Liang, Xiaofei
;
Wang, Beilei
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  |  
浏览/下载:43/0
  |  
提交时间:2021/04/26
An ultra-long circulating nanoparticle for reviving a highly selective BCR-ABL inhibitor in long-term effective and safe treatment of chronic myeloid leukemia
期刊论文
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2020, 卷号: 29
作者:
Fu, Liyi
;
Zou, Fengming
;
Liu, Qingwang
;
Wang, Beilei
;
Wang, Junqing
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/11/30
Chronic myeloid leukemia
BCR-ABL
Long-circulating nanoparticle
Drug delivery
Discovery of a highly potent and selective Bruton's tyrosine kinase inhibitor avoiding impairment of ADCC effects for B-cell non-Hodgkin lymphoma
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5
作者:
Liu, Juan
;
Liang, Qianmao
;
Wang, Aoli
;
Zou, Fengming
;
Qi, Ziping
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/11/30
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