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科研机构
山东大学 [5]
西安交通大学 [4]
大连理工大学 [2]
华中师范大学 [2]
内容类型
期刊论文 [8]
会议论文 [5]
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2019 [2]
2018 [1]
2017 [1]
2016 [2]
2014 [2]
2011 [2]
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Using CETSA assay and a mathematical model to reveal dual Bcl-2/Mcl-1 inhibition and on-target mechanism for ABT-199 and S1
期刊论文
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, 卷号: 142, 页码: 105105
作者:
Guo Zongwei
;
Song Ting
;
Xue Zuguang
;
Liu Peng
;
Zhang Minhang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/02
BH3 mimetics,Bcl-2 family proteins,CETSA,Mathematical modelling
Discovery of potent anti-inflammatory 4-(4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-yl) pyrimidin-2-amines for use as Janus kinase inhibitors.
期刊论文
Bioorganic & medicinal chemistry, 2019, 卷号: 27, 期号: 12, 页码: 2592-2597
作者:
Wang, Yazhou*
;
Huang, Wei*
;
Xin, Minhang
;
Chen, Pan
;
Gui, Li
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/23
Anti-inflammatory
Furo[3,2-c]pyridine
JAK inhibitor
Rheumatoid arthritis
Identification of JNK1 as a predicting biomarker for ABT-199 and paclitaxel combination treatment
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 155, 页码: 102-109
作者:
Song, Ting
;
Zhang, Minhang
;
Liu, Peng
;
Xue, Zhenyu
;
Fan, Yudan
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/02
Paclitaxel
ABT-199
Combination
JNK1
Biomarker
Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 页码: 75-83
作者:
Wang, Yazhou
;
Huang, Wei
;
Xin, Minhang
;
Chen, Pan
;
Gui, Li
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
4-(2-Furanyl)pyrimidin-2-amine
JAK2 inhibitor
4,5,6,7-Tetrahydro-furo[3,2-c]pyridine
Kinase selectivity
Synthesis and pharmacological evaluation of trifluoromethyl containing 4-(2-pyrimidinylamino)benzamides as Hedgehog signaling pathway inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: [db:dc_citation_issue], 页码: 1079-1088
作者:
Xin, Minhang
;
Zhang, Liandi
;
Wen, Jun
;
Shen, Han
;
Liu, Zhaoyu
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/02
SAR
Trifluoromethyl
Hedgehog signaling pathway inhibitors
In vivo
4-(2-Pyrimidinylamino)benzamide
Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors
期刊论文
Bioorganic and Medicinal Chemistry, 2016, 卷号: 25, 期号: 1, 页码: 75-83
作者:
Wang, Yazhou*
;
Huang, Wei*
;
Xin, Minhang
;
Chen, Pan
;
Gui, Li
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
JAK2 inhibitor
4-(2-Furanyl)pyrimidin-2-amine
4,5,6,7-Tetrahydro-furo[3,2-c]pyridine
Kinase selectivity
Design, synthesis, and biological study of 6,7-dihydro-5H-pyrano[2,3-d]pyrimidine derivatives as novel hedgehog signaling pathway inhibitors
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: [db:dc_citation_issue], 页码: 3784-3792
作者:
Xin, Minhang
;
Zhang, Liandi
;
Shen, Han
;
Wen, Jun
;
Tu, Chongxing
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
Novel
Hedgehog signaling pathway
6,7-Dihydro-5H-pyrano[2,3-d]pyrimidine
Inhibitors
Design, synthesis, and evaluation of pyrrolo[2,1-f][1,2,4]triazine derivatives as novel hedgehog signaling pathway inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: [db:dc_citation_issue], 页码: 1429-1440
作者:
Xin, Minhang
;
Zhang, Liandi
;
Tang, Feng
;
Tu, Chongxing
;
Wen, Jun
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/03
Novel
Hedgehog signaling pathway
Pyrrolo[2,1-f][1,2,4]triazine
Inhibitors
Analyse Volleyball Echelon Construction of Shandong Province
会议论文
International Conference on Materials, Mechatronics and Automation (ICMMA 2011), JAN 15-16, 2011
作者:
Liu Minhang
;
Yuan Shuping
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/31
volleyball
echelon building
discrete analysis
prediction
The Study on Development Crisis of Folk Sports Discipline System
会议论文
International Conference on Engineering Materials, Energy, Management and Control, JAN 22-23, 2011
作者:
Liu, Minhang
;
Li, Chutao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/31
systematic science
folk sports
discipline system
development crisis
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