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Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:
Wang, Z (Wang, Zhen)[ 1 ]
;
Jiang, XR (Jiang, Xiangrui)[ 1 ]
;
Zhang, XL (Zhang, Xianglei)[ 1,2 ]
;
Tian, GH (Tian, Guanghui)[ 3 ]
;
Yang, RL (Yang, Rulei)[ 3 ]
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浏览/下载:147/0
  |  
提交时间:2019/06/28
Influence of blood glucose fluctuation, C-peptide level and conventional risk factors on carotid artery intima-media thickness in Chinese Han patients with type 2 diabetes mellitus
期刊论文
European journal of medical research, 2019, 卷号: 24, 页码: 13
作者:
Liu Min[1]
;
Ao Li[2]
;
Hu Xinyu[3]
;
Ma Jianning[4]
;
Bao Kena[5]
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浏览/下载:91/0
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提交时间:2019/04/22
Blood glucose fluctuation
CIMT
T2DM
Thermal Emitting Strategy to Synthesize Atomically Dispersed Pt Metal Sites from Bulk Pt Metal
期刊论文
Journal of the American Chemical Society, 2019, 卷号: 141, 页码: 4505-4509
作者:
Qu Yunteng[1]
;
Chen Bingxu[2]
;
Li Zhijun[3]
;
Duan Xuezhi[4]
;
Wang Liguang[5]
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  |  
浏览/下载:103/0
  |  
提交时间:2019/04/22
Stacking of Tailored Chalcogenide Nanosheets around MoO2-C Conductive Stakes Modulated by a Hybrid POM subset of MOF Precursor Template: Composite Conversion-Insertion Cathodes for Rechargeable Mg-Li Dual-Salt Batteries
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2019, 卷号: 11, 页码: 5966-5977
作者:
Wu, Chenglong[1]
;
Hu, Jiulin[2]
;
Tian, Jing[3]
;
Chu, Fulu[4]
;
Yao, Zhenguo[5]
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浏览/下载:40/0
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提交时间:2019/04/22
Mg-Li dual-salt electrolyte
POM
MOF
NENU-5
chalcogenide cathodes
Mg-based batteries
Greatly Enhanced Faradic Capacities of 3D Porous Mn3O4/G Composites as Lithium-Ion Anodes and Supercapacitors by C-O-Mn Bonding
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2019, 卷号: 11, 页码: 10178-10188
作者:
Li, Shuang[1]
;
Yu, Li-Li[2]
;
Shi, Yu-Ting[3]
;
Fan, Jun[4]
;
Li, Rong-Bing[5]
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浏览/下载:31/0
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提交时间:2019/04/22
lithium-ion battery
supercapacitor
C-O-Mn
manganese oxides
Faradic reaction
IRF7 Gene Variations Confer Susceptibility to Autoimmune Thyroid Diseases and Graves' Ophthalmopathy
期刊论文
International journal of endocrinology, 2019, 卷号: 2019, 页码: 7429187
作者:
Yao Qiuming[1]
;
An Xiaofei[2]
;
Zhang Jing[3]
;
Mu Kaida[4]
;
Li Ling[5]
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浏览/下载:28/0
  |  
提交时间:2019/04/22
Hsp27 responds to and facilitates enterovirus A71 replication through enhancing viral IRES-mediated translation
期刊论文
Journal of virology, 2019
作者:
Dan Xuelian[1]
;
Wan Qianya[2]
;
Yi Lina[3]
;
Lu Jing[4]
;
Jiao Yang[5]
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  |  
浏览/下载:53/0
  |  
提交时间:2019/04/22
Application of Isothermal Nucleic Acid Signal Amplification in the Detection of Hepatocellular Carcinoma-Associated MicroRNA
期刊论文
CHEMPLUSCHEM, 2019, 卷号: 84, 页码: 8-17
作者:
Mao, Dongsheng[1]
;
Chen, Hong[2]
;
Tang, Yingying[3]
;
Li, Jingwen[4]
;
Cao, Ya[5]
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浏览/下载:23/0
  |  
提交时间:2019/04/22
cancer
isothermal nucleic acid signal amplification
microRNA
RNA recognition
tumor markers
CEP128 is a crucial risk locus for autoimmune thyroid diseases
期刊论文
Molecular and cellular endocrinology, 2019, 卷号: 480, 页码: 97-106
作者:
Wang Bin[1]
;
Jia Xi[2]
;
Yao Qiuming[3]
;
Li Qian[4]
;
He Weiwei[5]
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  |  
浏览/下载:40/0
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提交时间:2019/04/22
Autoimmune thyroids diseases
Centrosomal protein 128
Genetic predisposition
Graves' disease
Polymorphisms
Impact of PHEV in active distribution network under gas station network attack
期刊论文
ISA transactions, 2019
作者:
Li Xue[1]
;
Dong Jing[2]
;
Du Dajun[3]
;
Wu Lei[4]
;
Fei Minrui[5]
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  |  
浏览/下载:35/0
  |  
提交时间:2019/04/22
Attack
Correlation
Elementary transformation (ET)
Gas station network
Nataf/normalization transformation
Plug-in hybrid electric vehicle (PHEV)
Point estimate method (PEM)
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