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Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ]
收藏  |  浏览/下载:138/0  |  提交时间:2019/06/28
NIR-Light-Triggered Anticancer Strategy for Dual-Modality Imaging Guided Combination Therapy via a Bioinspired Hybrid PLGA Nanoplatform 期刊论文
2019, 卷号: 16, 期号: 3, 页码: 1367-1384
作者:  Shen, Xue[1];  Li, Tingting[1];  Chen, Zhongyuan[1];  Xie, Xiaoxue[1];  Zhang, Hanxi[1]
收藏  |  浏览/下载:28/0  |  提交时间:2019/12/06
ROCK isoforms differentially modulate cancer cell motility by mechanosensing the substrate stiffness 期刊论文
2019, 卷号: 88, 页码: 86-101
作者:  Peng, Yueting[1];  Chen, Zhongyuan[1];  Chen, Yu[1];  Li, Shun[1,3];  Jiang, Ying[1,3]
收藏  |  浏览/下载:35/0  |  提交时间:2019/12/06
Dendrimer-Functionalized Superparamagnetic Nanobeacons for Real-Time Detection and Depletion of HSP90 alpha mRNA and MR Imaging 期刊论文
2019, 卷号: 9, 期号: 20, 页码: 5784-5796
作者:  Chen, Zhongyuan[1];  Peng, Yueting[1];  Xie, Xiaoxue[1];  Feng, Yi[1];  Li, Tingting[1,3]
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/16
Highly efficient cascading synergy of cancer photo-immunotherapy enabled by engineered graphene quantum dots/photosensitizer/CpG oligonucleotides hybrid nanotheranostics 期刊论文
2019, 卷号: 205, 页码: 106-119
作者:  Wu, Chunhui[1,2];  Guan, Xiaotian[1];  Xu, Jiming[1];  Zhang, Yingxue[1];  Liu, Qiuyue[1]
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/06
Shear stress promotes anoikis resistance of cancer cells via caveolin-1-dependent extrinsic and intrinsic apoptotic pathways 期刊论文
2019, 卷号: 234, 期号: 4, 页码: 3730-3743
作者:  Li, Shun[1,3];  Chen, Yu[1];  Zhang, Yuehui[1];  Jiang, Xiaomin[1];  Jiang, Ying[1,3]
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/06
Recent advancements in mesoporous silica nanoparticles towards therapeutic applications for cancer 期刊论文
2019, 卷号: 89, 页码: 1-13
作者:  Li, Tingting[1,2,3];  Shi, Sixiang[2];  Goel, Shreya[4];  Shen, Xue[1];  Xie, Xiaoxue[1]
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/06
Differences between Motile and Nonmotile Cells of Haematococcus pluvialis in the Production of Astaxanthin at Different Light Intensities 期刊论文
2019, 卷号: 17, 期号: 1
作者:  Li, Feng[1,2,3,4];  Cai, Minggang[1,2,3,4,5];  Lin, Mingwei[4];  Huang, Xianghu[6];  Wang, Jun[5]
收藏  |  浏览/下载:16/0  |  提交时间:2019/12/26
Insights into disilylation and distannation: sequence influence and ligand/steric effects on Pd-catalyzed difunctionalization of carbenes 期刊论文
2018, 卷号: 47, 页码: 1819-1826
作者:  Yue, Xiaoyu[1];  Shan, Chunhui[1];  Qi, Xiaotian[1];  Luo, Xiaoling[2];  Zhu, Lei[1]
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/28
Etiology of community-acquired pneumonia in 1500 hospitalized children 期刊论文
Journal of medical virology, 2018, 卷号: 90, 页码: 421-428
作者:  Oumei Hao[1];  Xuefeng Wang[2];  Jianping Liu[3];  Kunling Shen[4];  Rong Ma[5]
收藏  |  浏览/下载:10/0  |  提交时间:2019/04/24


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