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Shabyar Ameliorates High Glucose Induced Retinal Pigment Epithelium Injury Through Suppressing Aldose Reductase and AMPK/mTOR/ULK1 Autophagy Pathway
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 期号: 5, 页码: 1-15
作者:
Liu, XY (Liu, Xiao Yan) [1] , [2] , [3]
;
Peng, J (Peng, Jun) [1] , [2]
;
He, F (He, Fei) [1]
;
Tursun, X (Tursun, Xirali) [4]
;
Li, SP (Li, Shu Ping) [1]
收藏
  |  
浏览/下载:132/0
  |  
提交时间:2022/06/06
shabyar
retinal pigment epithelium
autophagy
aldose reductase
traditional medicine formula
MGRL: Predicting Drug-Disease Associations Based on Multi-Graph Representation Learning
期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 4, 页码: 1-8
作者:
Zhao, BW (Zhao, Bo-Wei)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Wong, L (Wong, Leon)[ 1,2,3 ]
;
Zhang, P (Zhang, Ping)[ 4 ]
;
Li, HY (Li, Hao-Yuan)[ 5 ]
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/06
drug
disease
drug repositioning
multi-graph representation learning
graph embedding
LDGRNMF: LncRNA-disease associations prediction based on graph regularized non-negative matrix factorization
期刊论文
NEUROCOMPUTING, 2021, 卷号: 424, 期号: 2, 页码: 236-245
作者:
Wang, MN (Wang, Mei-Neng)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Wang, L (Wang, Lei)[ 2,3 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
;
Zheng, K (Zheng, Kai)[ 4 ]
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/03/05
LncRNA-disease associations
LncRNA-disease similarity
Nonnegative matrix factorization
Graph regularization
DBMDA: A Unified Embedding for Sequence-Based miRNA Similarity Measure with Applications to Predict and Validate miRNA-Disease Associations
期刊论文
MOLECULAR THERAPY-NUCLEIC ACIDS, 2020, 卷号: 19, 期号: 3, 页码: 602-611
作者:
Zheng, K (Zheng, Kai)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Wang, L (Wang, Lei)[ 2,3 ]
;
Zhou, Y (Zhou, Yong)[ 1 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/04/21
Identification of potential drug-targets by combining evolutionary information extracted from frequency profiles and molecular topological structures
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 卷号: 96, 期号: 2, 页码: 758-767
作者:
Wang, L (Wang, Lei)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
;
Yan, X (Yan, Xin)[ 3 ]
;
Zhang, W (Zhang, Wei)[ 1 ]
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/11/04
drug-target interaction
rotation forest
two-dimensional principal component analysis
Incorporating chemical sub-structures and protein evolutionary information for inferring drug-target interactions
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 1-11
作者:
Wang, L (Wang, Lei)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 2 ]
;
Li, LP (Li, Li-Ping)[ 2 ]
;
Yan, X (Yan, Xin)[ 3 ]
;
Zhang, W (Zhang, Wei)[ 1 ]
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/09
GANCDA: a novel method for predicting circRNA-disease associations based on deep generative adversarial network
期刊论文
INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS, 2020, 卷号: 23, 期号: 3, 页码: 265-283
作者:
Yan, X (Yan, Xin)[ 1 ]
;
Wang, L (Wang, Lei)[ 2,3 ]
;
You, ZH (You, Zhu-Hong)[ 3 ]
;
Li, LP (Li, Li-Ping)[ 3 ]
;
Zheng, K (Zheng, Kai)[ 4 ]
收藏
  |  
浏览/下载:261/0
  |  
提交时间:2020/12/11
circular RNA
diseases
CircRNA-disease association
generative adversarial network
logistic model tree
NLPEI: A Novel Self-Interacting Protein Prediction Model Based on Natural Language Processing and Evolutionary Information
期刊论文
EVOLUTIONARY BIOINFORMATICS, 2020, 卷号: 16, 期号: 12, 页码: 1-12
作者:
Jia, LN (Jia, Li-Na)[ 1 ]
;
Yan, X (Yan, Xin)[ 2,3 ]
;
You, ZH (You, Zhu-Hong)[ 4 ]
;
Zhou, X (Zhou, Xi)[ 4 ]
;
Li, LP (Li, Li-Ping)[ 4 ]
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/03/19
Self-interacting protein
natural language processing
evolutionary information
stacked auto-encoder
LMTRDA: Using logistic model tree to predict MiRNA-disease associations by fusing multi-source information of sequences and similarities
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2019, 卷号: 15, 期号: 3, 页码: 1-18
作者:
Wang, L (Wang, Lei)[ 1 ]
;
You, ZH (You, Zhu-Hong)[ 1 ]
;
Chen, X (Chen, Xing)[ 2 ]
;
Li, YM (Li, Yang-Ming)[ 3 ]
;
Dong, YN (Dong, Ya-Nan)[ 4 ]
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2019/05/16
Cluster analysis of Dendrobium officinale from different populations through agronomy characterization
期刊论文
Zhongguo Zhong yao za zhi, 2019, 卷号: 44, 页码: 53-58
作者:
Yu Wen-Xia[1]
;
Dong Xiao-Man[2]
;
Lei Zhou-Xi[3]
;
Yuan Yuan[4]
;
Shun Qing-Sheng[5]
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/04/22
Dendrobium officinale
cluster analysis
genetic similarities
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