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科研机构
北京航空航天大学 [9]
山东大学 [8]
兰州大学 [7]
大连理工大学 [3]
上海药物研究所 [3]
地质与地球物理研究所 [2]
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期刊论文 [47]
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2021 [2]
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2018 [9]
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2015 [3]
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Genomic alterations in biliary tract cancer predict prognosis and immunotherapy outcomes
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 卷号: 9
作者:
Chen, Xiaofeng
;
Wang, Deqiang
;
Liu, Jing
;
Qiu, Jingrong
;
Zhou, Jun
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/01/10
immunotherapy
tumor microenvironment
biomarkers
tumor
genetic markers
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
期刊论文
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:
Xiao,Shifu
;
Chan,Piu
;
Wang,Tao
;
Hong,Zhen
;
Wang,Shuzhen
收藏
  |  
浏览/下载:145/0
  |  
提交时间:2021/05/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and and in vivo study
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 2, 页码: 351-368
作者:
Wei, Peng
;
Liu, Bo
;
Wang, Ruifeng
;
Gao, Yinglei
;
Li, Lanlan
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2020/07/01
Fibroblast growth factor
Tyrosine kinase receptor
Structure-based
Crystallography
Selectivity
Hybrid
5-Hydrosulfonyl-5H- pyrrolo[2.3-b]pyrazine
Inhibitor
Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitors
期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 50, 页码: 28961-28986
作者:
Jiang, Xiangyi
;
Wu, Gaochan
;
Zalloum, Waleed A.
;
Meuser, Megan E.
;
Dick, Alexej
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  |  
浏览/下载:13/0
  |  
提交时间:2019/12/11
Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors by exploring the structure-activity relationship of solvent-exposed regions I
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 93, 期号: 4, 页码: 430-437
作者:
Kang, Dongwei
;
Wang, Zhao
;
Chen, Meng
;
Feng, Da
;
Wu, Gaochan
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
DAPY
HIV-1
NNRTIs
solvent-exposed region I
thiophene[3
2-d]pyrimidine
Contemporary medicinal-chemistry strategies for the discovery of selective butyrylcholinesterase inhibitors
期刊论文
DRUG DISCOVERY TODAY, 2019, 卷号: 24, 期号: 2, 页码: 629-635
作者:
Jing, Lanlan
;
Wu, Gaochan
;
Kang, Dongwei
;
Zhou, Zhongxia
;
Song, Yuning
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
Recent applications of click chemistry in drug discovery
期刊论文
EXPERT OPINION ON DRUG DISCOVERY, 2019, 卷号: 14, 期号: 8, 页码: 779-789
作者:
Jiang, Xiangyi
;
Hao, Xia
;
Jing, Lanlan
;
Wu, Gaochan
;
Kang, Dongwei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
CuAAC
Click chemistry
Medicinal chemistry
Drug design
Bioorthogonal
reactions
Bioinspired membranes for multi-phase liquid and molecule separation
期刊论文
SCIENCE CHINA-CHEMISTRY, 2019, 卷号: 62, 页码: 14-23
作者:
Liu, Jingchong
;
Cui, Zhimin
;
Hou, Lanlan
;
Li, Dianming
;
Gao, Yuan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/30
bioinspired
superhydrophobic
superwettability
nanofibers
separation membrane
Interpenetrating Janus Membrane for High Rectification Ratio Liquid Unidirectional Penetration
期刊论文
ACS NANO, 2019, 卷号: 13, 页码: 4124-4132
作者:
Hou, Lanlan
;
Wang, Nu
;
Man, Xingkun
;
Cui, Zhimin
;
Wu, Jing
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/30
unidirectional penetration
Laplace pressure
wettability
electrospinning
nanofibers
discoveryofaseriesofdimethoxybenzenefgfrinhibitorswith5hpyrrolo23bpyrazinescaffoldstructureactivityrelationshipcrystalstructuralcharacterizationandinvivostudy
期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 2, 页码: 351
作者:
Wei Peng
;
Liu Bo
;
Wang Ruifeng
;
Gao Yinglei
;
Li Lanlan
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Fibroblast growth factor
Tyrosine kinase receptor
Structure-based
Crystallography
Selectivity
Hybrid
5-Hydrosulfonyl-5Hpyrrolo 2
3-bpyrazine
Inhibitor
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