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Characterization of oxidative damage induced by nanoparticles via mechanism-driven machine learning approaches
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 871, 页码: 11
作者:
Wang, Xiaoqing
;
Li, Fei
;
Teng, Yuefa
;
Ji, Chenglong
;
Wu, Huifeng
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/01/26
Toxic effects
Machine learning
Risk assessment
Mechanism -driven analysis
TiO2-based engineered nanoparticles(nTiO2)
Potential adverse outcome pathways with hazard identification of organophosphate esters
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 851, 页码: 13
作者:
Wang, Xiaoqing
;
Li, Fei
;
Teng, Yuefa
;
Ji, Chenglong
;
Wu, Huifeng
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/01/11
Organophosphate esters (OPEs)
Network-centric analysis
Risk assessment
Adverse outcome pathway
Quantitative weight of evidence
Critical features identification for chemical chronic toxicity based on mechanistic forecast models
期刊论文
ENVIRONMENTAL POLLUTION, 2022, 卷号: 307, 页码: 8
作者:
Wang, Xiaoqing
;
Li, Fei
;
Chen, Jingwen
;
Teng, Yuefa
;
Ji, Chenglong
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/07/26
Computational toxicology
Machine learning
Structural alerts
Risk assessment
Prioritization rank
Critical target identification and human health risk ranking of metal ions based on mechanism-driven modeling
期刊论文
CHEMOSPHERE, 2022, 卷号: 301, 页码: 9
作者:
Wang, Xiaoqing
;
Teng, Yuefa
;
Ji, Chenglong
;
Wu, Huifeng
;
Li, Fei
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/07/26
Metal ions
p53
QSAR
Genetic toxicity
Human health risk
Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022
期刊论文
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: D1, 页码: D27-D38
作者:
Xue, Yongbiao
;
Bao, Yiming
;
Zhang Zhang
;
Zhao, Wenming
;
Xiao, Jingfa
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  |  
浏览/下载:50/0
  |  
提交时间:2022/04/02
Toxicity pathways of lipid metabolic disorders induced by typical replacement flame retardants via data-driven analysis, in silico and in vitro approaches
期刊论文
CHEMOSPHERE, 2022, 卷号: 287, 页码: 9
作者:
Wang, Xiaoqing
;
Wang, Li
;
Li, Fei
;
Teng, Yuefa
;
Ji, Chenglong
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/06/16
Toxicity pathways
Lipid metabolism disorder
Bibliometric analysis
Computational toxicology
Data-driven analysis
Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022
期刊论文
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: D1, 页码: D27-D38
作者:
Xue, Yongbiao
;
Bao, Yiming
;
Zhang Zhang
;
Zhao, Wenming
;
Xiao, Jingfa
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/07
DAGM: A novel modelling framework to assess the risk of HER2-negative breast cancer based on germline rare coding mutations
期刊论文
EBIOMEDICINE, 2021, 卷号: 69, 页码: 11
作者:
Yang, Mei
;
Fan, Yanhui
;
Wu, Zhi-Yong
;
Gu, Jin
;
Feng, Zhendong
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/12/01
HER2-negative breast cancer
Germline rare coding mutations
Damage assessment of genomic mutations (DAGM)
Risk assessment
Activity profiles of signalling pathways (APSP)
HER2 signalling pathway
Immune suppression
Rare variants in the germline genome holistically determine receptor-independent Her2 signaling pathway activation and immune suppression, shaping pathological type and risk of HER2-negative breast cancer
期刊论文
CANCER RESEARCH, 2021, 卷号: 81, 期号: 4, 页码: 1
作者:
Yang, Mei
;
Fan, Yanhui
;
Wu, Zhi-Yong
;
Feng, Zhendong
;
Zhang, Qiangzu
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/12/01
Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2021
期刊论文
NUCLEIC ACIDS RESEARCH, 2021, 卷号: 49, 期号: D1, 页码: D18-D28
作者:
Xue, Yongbiao
;
Bao, Yiming
;
Zhang, Zhang
;
Zhao, Wenming
;
Xiao, Jingfa
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/12/01
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