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Construction of a Quantitative Structure Activity Relationship (QSAR) Model to Predict the Absorption of Cephalosporins in Zebrafish for Toxicity Study 期刊论文
2019, 卷号: 10, 页码: 31
作者:  Liu, Ying;  Zhang, Xia;  Zhang, Jingpu;  Hu, Changqin
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/03
Validated LC-MS/MS method for simultaneous analysis of 21 cephalosporins in zebrafish for a drug toxicity study 期刊论文
2018, 卷号: 558, 页码: 28-34
作者:  Liu, Ying;  Zhang, Jingpu;  Hu, Changqin
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/03
Relationship Between Fluoroquinolone Structure and Neurotoxicity Revealed by Zebrafish Neurobehavior 期刊论文
2018, 卷号: 31, 期号: 4, 页码: 238-250
作者:  Xiao, Chaoqiang;  Han, Ying;  Liu, Ying;  Zhang, Jingpu;  Hu, Changqin
收藏  |  浏览/下载:2/0  |  提交时间:2020/01/03
Cardiac safety evaluation in zebrafish and in silico ADME prediction of cephalosporins with an aminothiazoyl ring at the C-7 position 期刊论文
2018, 卷号: 347, 页码: 33-44
作者:  Han, Ying;  Chen, Bo;  Zhang, Jingpu;  Hu, Changqin
收藏  |  浏览/下载:8/0  |  提交时间:2020/01/03
A systematic toxicity evaluation of cephalosporins via transcriptomics in zebrafish and in silico ADMET studies 期刊论文
2018, 卷号: 116, 期号: Pt B, 页码: 264-271
作者:  Han, Ying;  Zhang, Jingpu;  Hu, Changqin
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/03
Neurobehavioral Effects of Cephalosporins: Assessment of Locomotors Activity, Motor and Sensory Development in Zebrafish 期刊论文
2018, 卷号: 9, 页码: 160
作者:  Han, Ying;  Zheng, Yangmin;  Zhang, Jingpu;  Hu, Changqin
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/03
Toxic effect prediction of cefatirizine amidine sodium and its impurities by structure-toxicity relationship of cephalosporins 期刊论文
2018, 卷号: 46, 页码: 137-147
作者:  Qian, Jianqin;  Han, Ying;  Li, Jin;  Zhang, Jingpu;  Hu, Changqin
收藏  |  浏览/下载:13/0  |  提交时间:2020/01/03
Determination of Relative Response Factors of Cefazolin Impurities by Quantitative NMR 期刊论文
AAPS PharmSciTech, 2017, 卷号: 18, 页码: 1895-1900
作者:  Liu Shuyu[1];  Yao Shangchen[2];  Zhang Hailing[3];  Hu Changqin[4]
收藏  |  浏览/下载:3/0  |  提交时间:2019/04/26
HPLC  RRF  qNMR  uncertainty  
Identification of impurities in macrolides by liquid chromatography-mass spectrometric detection and prediction of retention times of impurities by constructing quantitative structure-retention relationship (QSRR) 期刊论文
2017, 卷号: 145, 页码: 262-272
作者:  Zhang, Xia;  Li, Jin;  Wang, Chen;  Song, Danqing;  Hu, Changqin
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/03
Structure-toxicity relationship of cefoperazone and its impurities to developing zebrafish by transcriptome and Raman analysis 期刊论文
2017, 卷号: 327, 页码: 39-51
作者:  Han Ying;  Qian Jianqin;  Zhang Jingpu;  Hu Changqin;  Wang Chen
收藏  |  浏览/下载:2/0  |  提交时间:2020/01/04


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