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科研机构
山东大学 [26]
中国医学科学院 北京... [1]
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期刊论文 [25]
会议论文 [2]
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2019 [6]
2018 [3]
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Design, synthesis, and biological evaluation of 2-(5-methyl-1H-pyrazol-1-yl) acetamide derivatives as androgen receptor antagonists
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2019, 卷号: 28, 期号: 3, 页码: 380-386
作者:
Dong, Junze
;
Zhang, Jingya
;
Li, Zilu
;
Asnake, Solomon
;
Zhang, Daoguang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/11
Androgen receptor
Prostate cancer
Antagonists
Pyrazole derivatives
Discovery of novel pyrazole derivatives as potential anticancer agents in MCL
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 9, 页码: 1060-1064
作者:
Ran, Fansheng
;
Liu, Yang
;
Zhang, Daoguang
;
Liu, Meixia
;
Zhao, Guisen
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/12/11
Mantle cell lymphoma
BTK
Irreversible inhibitors
Anticancer
Pyrazole
derivatives
Discovery of pyrazolopyrimidine derivatives as potent BTK inhibitors with effective anticancer activity in MCL
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 89
作者:
Ran, Fansheng
;
Liu, Yang
;
Liu, Meixia
;
Zhang, Daoguang
;
Wang, Peng
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
Mantle cell lymphoma
BTK inhibitors
Anticancer
Selectivity
Patient
cells
Recent Advance of Akt Inhibitors in Clinical Trials
期刊论文
CHEMISTRYSELECT, 2019, 卷号: 4, 期号: 31, 页码: 9040-9044
作者:
Guo, Kaiwen
;
Tang, Wendi
;
Zhuo, Huijun
;
Zhao, Guisen
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
antitumor agents
clinical trials
inhibitors
protein kinase B
Virtual Observation Method and Precision Estimation for Ill-Posed Partial EIV Model
期刊论文
JOURNAL OF SURVEYING ENGINEERING, 2019, 卷号: 145, 期号: 4
作者:
Wang, Leyang
;
Wen, Guisen
;
Zhao, Yingwen
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
Ill-posed problem
Partial error-in-variables (EIV) model
Virtual
observation
Nonlinear
Design, synthesis and biological evaluation of novel 2,3-indolinedione derivatives against mantle cell lymphoma
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3319-3327
作者:
Yu, Shengping
;
Liu, Yang
;
Zhang, Zhen
;
Zhang, Jingya
;
Zhao, Guisen
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
2,3-Indolinedione
Mantle cell lymphoma
Derivatives
Biological
activities
Discovery of novel 5-methyl-1H-pyrazole derivatives as potential antiprostate cancer agents: Design, synthesis, molecular modeling, and biological evaluation
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 卷号: 91, 期号: 6, 页码: 1113-1124
作者:
Zhang, Daoguang
;
Asnake, Solomon
;
Zhang, Jingya
;
Olsson, Per-Erik
;
Zhao, Guisen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
androgen receptor
AR antagonist
luciferase reporter gene assay
prostate cancer
pyrazole derivative
Design, synthesis and biological evaluation of AKT inhibitors bearing a piperidin-4-yl appendant
期刊论文
MEDCHEMCOMM, 2018, 卷号: 9, 期号: 8, 页码: 1340-1350
作者:
Zhang, Daoguang
;
Tong, Dongdong
;
Yang, Dezhi
;
Sun, Jing
;
Zhang, Fenghe
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
Targeting Bruton's tyrosine kinase for the treatment of B cell associated malignancies and autoimmune diseases: Preclinical and clinical developments of small molecule inhibitors
期刊论文
ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 7
作者:
Zhang, Zhen
;
Zhang, Daoguang
;
Liu, Yang
;
Yang, Dezhi
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
arthritis
Bruton's tyrosine kinase
BTK inhibitor
leukemia
lymphoma
Design, synthesis, and evaluation of novel Akt1 inhibitors based on an indole scaffold
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 5, 页码: 791-803
作者:
Yang, Dezhi
;
Tong, Dongdong
;
Zhang, Qian
;
Wang, Yongtao
;
Sun, Jing
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/12
Akt1 inhibitors
antiproliferative activity
GSK3
indole scaffold
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