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科研机构
华南理工大学 [9]
暨南大学 [8]
江苏大学 [5]
重庆大学 [3]
复旦大学上海医学院 [1]
内容类型
期刊论文 [26]
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2017 [4]
2016 [4]
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2010 [1]
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浏览/检索结果:
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Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 页码: 4100-4109
作者:
Yuan, Zigao[1,2]
;
Chen, Shaopeng[2]
;
Sun, Qinsheng[2,3]
;
Wang, Ning[1,2]
;
Li, Dan[1,2]
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/04/24
PARP
HDAC
Multitarget
Drug design
Antitumor
Design, synthesis and biological evaluation of 4-amidobenzimidazole acridine derivatives as dual PARP and Topo inhibitors for cancer therapy
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 1135-1146
作者:
Yuan, Zigao[1,2]
;
Chen, Shaopeng[2]
;
Chen, Changjun[2]
;
Chen, Jiwei[1,2]
;
Chen, Chengken[1,2]
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/04/24
Topo
PARP
Multitarget
Acridines
Antitumor bioactivity
Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 281-292
作者:
Yuan, Zigao[1,2]
;
Sun, Qinsheng[2,3]
;
Li, Dan[1,2]
;
Miao, Shuangshuang[2]
;
Chen, Shaopeng[2]
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/04/24
Epigenetic targets
Multi-target
Drug design
Antitumor bioactivity
DNMT
HDAC
Synthesis and biological research of novel azaacridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 页码: 3437-3446
作者:
Li, Dan[1,2,3]
;
Yuan, Zigao[1,2,3]
;
Chen, Shaopeng[2,3]
;
Zhang, Cunlong[3]
;
Song, Lu[1,2,3]
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/04/24
Azaacridine derivatives
Molecular docking
DNA binding
Topoisomerase II inhibitor
Antiproliferative activity
Relationship between Blood Pressure and Outcomes in Acute Ischemic Stroke Patients Administered Lytic Medication in the TIMSChina Study
期刊论文
PLoS ONE, 2016, 卷号: 11, 期号: 2
作者:
Wu, Wei/57145424800[0]
;
Huo, Xiaochuan/57146684200[1]
;
Zhao, Xingquan/7407574974[2]
;
Liao, Xiaoling/56509824200[3]
;
Wang, Chunjuan/26647866700[4]
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/12/05
A simple benzimidazole quinoline-conjugate fluorescent chemosensor for highly selective detection of Ag+ (SCI收录)
期刊论文
TETRAHEDRON, 2016, 卷号: 72, 页码: 3980-3985
作者:
Chen, Changjun[1,2]
;
Liu, Haiyang[1,2]
;
Zhang, Bin[2,3]
;
Wang, Yanwei[1,2]
;
Cai, Kai[1,2]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/24
Fluorescence chemosensor
Silver ion
Turn-on effect
High selectivity
Synthesis and antiproliferative activity of 9-benzylamino-6-chloro-2-methoxy-acridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 116, 页码: 59-70
作者:
Zhang, Wei[1,2,3]
;
Zhang, Bin[3]
;
Zhang, Wei[1,2,3]
;
Yang, Ti[1]
;
Wang, Ning[1,2]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/24
Acridine derivatives
Topoisomerase II inhibitor
Antiproliferative activity
DNA damage
Exposure of CCRF-CEM cells to acridone derivative 8a triggers tumor death via multiple mechanisms
期刊论文
PROTEOMICS, 2016, 卷号: 16, 页码: 1177-1190
作者:
Wang, Yini[1,2]
;
Gao, Dan[2,3]
;
Chu, Bizhu[2,3]
;
Gao, Chunmei[3]
;
Cao, Deliang[4]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/24
Acridone derivative 8a
Biomedicine
2D nano LC-MS
DNA damage
Energy metabolism
Oxidative stress
PKU-3: An HCl-Inclusive Aluminoborate for Strecker Reaction Solved by Combining RED and PXRD
期刊论文
2015, 卷号: 137, 页码: 7047-7050
作者:
Chen, Hong[1,5]
;
Ju, Jing[2]
;
Meng, Qingpeng[1]
;
Su, Jie[1]
;
Lin, Cong[2,3]
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/11/30
Sparse whole-genome sequencing identifies two loci for major depressive disorder
期刊论文
2015, 卷号: 523, 期号: [db:dc_citation_issue], 页码: 588
作者:
Cai, Na[1]
;
Bigdeli, Tim B.[2]
;
Kretzschmar, Warren[1]
;
Li, Yihan[1]
;
Liang, Jieqin[3]
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/12/03
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