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科研机构
山东大学 [14]
复旦大学上海医学院 [10]
西安交通大学 [2]
内容类型
期刊论文 [26]
发表日期
2019 [2]
2018 [6]
2017 [2]
2016 [7]
2015 [6]
2014 [1]
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Government institutional support, entrepreneurial orientation, strategic renewal, and firm performance in transitional China
期刊论文
INTERNATIONAL JOURNAL OF ENTREPRENEURIAL BEHAVIOR & RESEARCH, 2019, 卷号: 25, 页码: 433-456
作者:
Shu, Chengli
;
De Clercq, Dirk
;
Zhou, Yunyue
;
Liu, Cuijuan
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/11/19
Entrepreneurial orientation
Corporate entrepreneurship Intrapreneurship
Developing countries
Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 3, 页码: 447-456
作者:
Wang, Zhao
;
Yu, Zhao
;
Kang, Dongwei
;
Zhang, Jian
;
Tian, Ye
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
HIV-1
NNRTIs
Doravirine
Acetamide
Prodrug
Drug design
When is job control most useful for idea championing? Role conflict and psychological contract violation effects
期刊论文
Journal of Management and Organization, 2018, 页码: 1-15
作者:
De Clercq, Dirk
;
Sun, Wei
;
Belausteguigoitia, Imanol
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/11/26
idea championing
job control
psychological contract violation
role conflict
Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutant virus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 151, 页码: 339-350
作者:
Tian, Ye
;
Liu, Zhaoqiang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
HIV-1
NNRTIs
Triazole
Diarylnicotinamide
Entrance channel
Drug
design
First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strain
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 8, 页码: 1348-1351
作者:
Huang, Boshi
;
Liu, Xinhao
;
Tian, Ye
;
Kang, Dongwei
;
Zhou, Zhongxia
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
HIV-1 NNRTI
RDEA427
Carbonate prodrug
Anti-HIV activity
Metabolic
stability
Discovery of novel diarylpyrimidines as potent HIV-1 NNRTIs by investigating the chemical space of a less explored "hydrophobic channel"
期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 卷号: 16, 期号: 6, 页码: 1014-1028
作者:
Zhou, Zhongxia
;
Liu, Tao
;
Kang, Dongwei
;
Huo, Zhipeng
;
Wu, Gaochan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 155, 页码: 714-724
作者:
Sun, Lin
;
Gao, Ping
;
Dong, Guanyu
;
Zhang, Xujie
;
Cheng, Xiqiang
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
HAART
HIV-1 dual inhibitors
HIV-1 IN
RNase H
5-hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives
Privileged
structure
The discovery of novel diarylpyri(mi) dine derivatives with high level activity against a wide variety of HIV-1 strains as well as against HIV-2
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2051-2060
作者:
Lu, Xueyi
;
Yang, Jiapei
;
Kang, Dongwei
;
Gao, Ping
;
Daelemans, Dirk
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
HIV-1
HIV-2
NNRTIs
DAPY
Drug design
Entrance channel
Discovery of novel DAPY-IAS hybrid derivatives as potential HIV-1 inhibitors using molecular hybridization based on crystallographic overlays
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 16, 页码: 4397-4406
作者:
Huang, Boshi
;
Wang, Xueshun
;
Liu, Xinhao
;
Chen, Zihui
;
Li, Wanzhuo
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
HIV-1 inhibitors
DAPY-IAS hybrids
Crystallographic overlays
Drug
design
SARs
Molecular modeling
Design, synthesis and anti-HIV evaluation of novel diarylpyridine derivatives as potent HIV-1 NNRTIs
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 383-391
作者:
Liu, Zhaoqiang
;
Tian, Ye
;
Liu, Jinghan
;
Huang, Boshi
;
Kang, Dongwei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/12
HlV-1
NNRTIs
Pyridine
Bioisosteric principle
Drug design
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