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Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235
作者:
Qu, Bingxue
;
Xu, Yongjin
;
Lu, Yang
;
Zhuang, Weihao
;
Jin, Xinxin
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/12/23
XPO1
Multiple myeloma
MM.1S
N-phenylsulfonamide
Oral administration
Genome size evolution of the extant lycophytes and ferns
期刊论文
PLANT DIVERSITY, 2022, 卷号: 44, 期号: 2, 页码: 141-152
作者:
Wang, Fa-Guo
;
Wang, Ai-Hua
;
Bai, Cheng-Ke
;
Jin, Dong-Mei
;
Nie, Li-Yun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/07
Genome size
Ferns
Chromosome numbers
Habitat type
Whole-genome duplications
Evolution
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
Expert consensus workshop report: Guidelines for thermal ablation of thyroid tumors (2019 edition)
期刊论文
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, 2020, 卷号: 16
作者:
Xu, Dong
;
Ge, Minghua
;
Yang, Ankui
;
Cheng, Ruochuan
;
Sun, Hui
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2020/11/30
Ablation techniques
consensus
guideline
nodular goiter
thyroid neoplasms
fDiscovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 72-85
作者:
Zhan, Wenhu
;
Che, Jinxin
;
Xu, Lei
;
Wu, Yizhe
;
Hu, Xiaobei
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Pyrazole-thiophene derivatives
Akt inhibitor
Antitumor
Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based Design
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7264-7288
作者:
Dong, Xiaowu
;
Zhan, Wenhu
;
Zhao, Mengting
;
Che, Jinxin
;
Dai, Xiaoyang
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  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
Covalent docking modelling-based discovery of tripeptidyl epoxyketone proteasome inhibitors composed of aliphatic-heterocycles
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 602-614
作者:
Dong, Xiao-Wu
;
Zhang, Jian-Kang
;
Xu, Lei
;
Che, Jin-Xin
;
Cheng, Gang
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  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
Proteasome inhibitors
Tripeptide
Covalent docking
Interaction mode
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