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A phase Ib/II study of AK112, a PD-1/VEGF bispecific antibody, as first- or second-line therapy for advanced non-small cell lung cancer (NSCLC).
期刊论文
JOURNAL OF CLINICAL ONCOLOGY, 2022, 卷号: 40
作者:
Zhou, Caicun
;
Ren, Shengxiang
;
Luo, Yongzhong
;
Wang, Lei
;
Xiong, Anwen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/12/23
Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib
期刊论文
BMC CANCER, 2022, 卷号: 22
作者:
Jin, Ying
;
Lin, Chen
;
Shi, Xun
;
He, Qiong
;
Yan, Junrong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/23
Clinical and molecular features
Efficacy and outcome
EGFR T790M mutation
Non-small-cell lung cancer
Osimertinib
Dual activation of Hedgehog and Wnt/beta-catenin signaling pathway caused by downregulation of SUFU targeted by miRNA-150 in human gastric cancer
期刊论文
AGING-US, 2021, 卷号: 13, 期号: 7, 页码: 10749-10769
作者:
Peng, Yin
;
Zhang, Xiaojing
;
Lin, Huijuan
;
Deng, Shiqi
;
Qin, Ying
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/12/01
miRNA-150
SUFU
Wnt/beta-catenin
hedgehog
EMT
Histone methyltransferase SET8 is regulated by miR-192/215 and induces oncogene-induced senescence via p53-dependent DNA damage in human gastric carcinoma cells
期刊论文
CELL DEATH & DISEASE, 2020, 卷号: 11, 期号: 10, 页码: 15
作者:
Zhang, Xiaojing
;
Peng, Yin
;
Yuan, Yuan
;
Gao, Yuli
;
Hu, Fan
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/12/01
SUFU mediates EMT and Wnt/beta-catenin signaling pathway activation promoted by miRNA-324-5p in human gastric cancer
期刊论文
CELL CYCLE, 2020, 页码: 14
作者:
Peng, Yin
;
Zhang, Xiaojing
;
Lin, Huijuan
;
Deng, Shiqi
;
Qin, Ying
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/12/10
miRNA-324-5p
SUFU negative regulator of hedgehog signaling
Wnt/beta-catenin
EMT
miRNA-192 and-215 activate Wnt/beta-catenin signaling pathway in gastric cancer via APC
期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2020, 卷号: 235, 期号: 9, 页码: 6218-6229
作者:
Deng, Shiqi
;
Zhang, Xiaojing
;
Qin, Ying
;
Chen, Wangchun
;
Fan, Hu
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2020/12/10
APC
gastric cancer
miRNA-192 and-215
Wnt signaling pathway
cfDNA changes for monitoring of targeted therapy in a primary EGFR mutation lung adenocarcinoma
期刊论文
TRANSLATIONAL LUNG CANCER RESEARCH, 2020, 卷号: 9
作者:
He, Qiong
;
Zhu, Xian
;
Shi, Xun
;
Lin, Chen
;
Jin, Yin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/11/26
Tumor Mutation Burden Correlates With Efficacy of Chemotherapy/Targeted Therapy in Advanced Non-Small Cell Lung Cancer
期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:
Lin, Chen
;
Shi, Xun
;
Zhao, Jun
;
He, Qiong
;
Fan, Yun
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/10/26
tumor mutation burden (TMB)
clinical benefit
epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs)
chemotherapy
non-small cell lung cancer (NSCLC)
Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation
期刊论文
ONCOGENE, 2020, 卷号: 39
作者:
Jin, Ying
;
Bao, Hua
;
Le, Xiuning
;
Fan, Xiaojun
;
Tang, Ming
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/11/26
Mathematical Programs with Second-Order Cone Complementarity Constraints: Strong Stationarity and Approximation Method
期刊论文
JOURNAL OF OPTIMIZATION THEORY AND APPLICATIONS, 2019, 卷号: 181, 期号: 2, 页码: 521-540
作者:
Zhu, Xide
;
Zhang, Jin
;
Zhou, Jinchuan
;
Yang, Xinmin
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  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
Mathematical programs with second-order cone complementarity
constraints
Stationarity conditions
Jordan product
Calmness
conditions
Approximation methods
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