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上海药物研究所 [9]
北京大学 [8]
大连理工大学 [5]
金属研究所 [2]
烟台海岸带研究所 [2]
河北大学 [1]
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期刊论文 [25]
会议论文 [2]
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Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 844-847
作者:
Wang, Xiaowen
;
Su, Mingbo
;
Li, You
;
Liu, Tongchao
;
Wang, Yujie
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
LSD1 inhibitor
Tranylcypromine
Menin-MLL1 protei n-protein interaction inhibitor
MV4-11 antiproliferative activity
Structure activity relationship
Stereoselective N-glycosylation with N-4-acyl cytosines and efficient synthesis of gemcitabine
期刊论文
TETRAHEDRON, 2019, 卷号: 75, 期号: 9, 页码: 1203-1213
作者:
Liu, Tongchao
;
Tang, Jiadeng
;
Liang, Jianpeng
;
Chen, Yabin
;
Wang, Xiaowen
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
Stereoselective
N-glycosylation
N-4-acyl cytosine
Nucleoside
Gemcitabine
Efficient syntheses of alpha- and beta-C-nucleosides and the origin of anomeric selectivity
期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2018, 卷号: 5, 期号: 12, 页码: 1992-1999
作者:
Liu, Tongchao
;
Zhu, Zhengdan
;
Ren, Huanming
;
Chen, Yabin
;
Chen, Guohua
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Convenient preparation of pinometostat and related 5 '-deoxy-5 '-amino adenosine derivatives as well as their activity against DOT1L
期刊论文
TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 4, 页码: 415-417
作者:
Liu, Tongchao
;
Ren, Huanming
;
Li, Cong
;
Chen, Guohua
;
Cheng, Maosheng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
DOTI L inhibitor
Pinometostat
Amination
5 '-Deoxy-5 '-amino adenosine derivative
Structure activity relationship
内地生源汉族大学生高原习服相关指标跟踪调查*
期刊论文
2018, 卷号: 第4期, 页码: 323-326
作者:
赵清华
;
阿旺曲扎
;
旦增罗布
;
巴桑
;
平措
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/04/15
高原
习服
汉族
藏族
血压
肺活量
血氧饱和度
Preparation of 5 '-deoxy-5 '-amino-5 '-C-methyl adenosine derivatives and their activity against DOT1L
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 22, 页码: 4960-4963
作者:
Liu, Tongchao
;
Xie, Wuchen
;
Li, Cong
;
Ren, Huanming
;
Mao, Yudong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
5'-Deoxy-5'-amino-5'-C-methyl adenosine derivative
N-glycosylation
Nucleoside synthesis
DOT1L inhibitor
Structure activity relationship
Discovery and Biological Evaluation of a Series of Pyrrolo[2,3-b]pyrazines as Novel FGFR Inhibitors
期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 4
作者:
Zhang, Yan
;
Liu, Hongchun
;
Zhang, Zhen
;
Wang, Ruifeng
;
Liu, Tongchao
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
FGFR1
inhibitor
kinase inhibitor
pyrazine
hinge binder
Urban air pollution and health risks of parent and nitrated polycyclic aromatic hydrocarbons in two megacities, southwest China
期刊论文
ATMOSPHERIC ENVIRONMENT, 2017
Zhuo, Shaojie
;
Du, Wei
;
Shen, Guofeng
;
Wang, Rui
;
Pan, Xuelian
;
Li, Tongchao
;
Han, Yang
;
Li, Yungui
;
Pan, Bo
;
Peng, Xing
;
Cheng, Hefa
;
Wang, Xilong
;
Shi, Guoliang
;
Xing, Baoshan
;
Tao, Shu
收藏
  |  
浏览/下载:119/0
  |  
提交时间:2017/12/03
Urban air pollution
PAHs
Nitrated PAHs
Southwest China
Non-priority PAHs
Risk assessment
OXY-PAH EMISSIONS
CANCER-RISK
TIBETAN PLATEAU
NORTHERN CHINA
SOURCE APPORTIONMENT
SPATIAL-DISTRIBUTION
ORGANIC POLLUTANTS
SEASONAL-VARIATION
WOOD COMBUSTION
AMBIENT AIR
Source-oriented risk assessment of inhalation exposure to ambient polycyclic aromatic hydrocarbons and contributions of non-priority isomers in urban Nanjing, a megacity located in Yangtze River Delta, China
期刊论文
ENVIRONMENTAL POLLUTION, 2017
Zhuo, Shaojie
;
Shen, Guofeng
;
Zhu, Ying
;
Du, Wei
;
Pan, Xuelian
;
Li, Tongchao
;
Han, Yang
;
Li, Bengang
;
Liu, Junfeng
;
Cheng, Hefa
;
Xing, Baoshan
;
Tao, Shu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
Polycyclic aromatic hydrocarbons
Non-priority isomers
Source-oriented risk assessment
Increment lifetime cancer risk
Dibenzopyrene
2-DIMENSIONAL GAS-CHROMATOGRAPHY
STANDARD REFERENCE MATERIALS
FLIGHT MASS-SPECTROMETRY
MOLECULAR-WEIGHT 302
LUNG-CANCER RISK
PARTICULATE MATTER
SOURCE APPORTIONMENT
EMISSION FACTORS
NORTHERN CHINA
ENVIRONMENTAL-SAMPLES
A one-pot synthesis of omarigliptin and its analogues through stabilized beta-amino ketone intermediate
期刊论文
SYNTHETIC COMMUNICATIONS, 2017, 卷号: 47, 期号: 4, 页码: 357-363
作者:
Li, You
;
Liu, Tongchao
;
Li, Chungang
;
Xiong, Bing
;
Zhao, Dongmei
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Beta-amino ketone
omarigliptin
one pot synthesis
reductive amination
stabilization effect
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