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CORC

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Scalable Process for Making 5,7-Dichlorotetrahydroisoquinoline-6-carboxylic Acid Using Methylene as the Protecting Group 期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2447-2452
作者:  Xu, Wanbin;  Gong, Xudong;  Odilov, Abdullajon;  Hu, Tianwen;  Jiang, Xiangrui
收藏  |  浏览/下载：53/0  |  提交时间：2022/01/18
Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2 期刊论文
CELL RESEARCH, 2021, 页码: 3
作者:  Xie, Yuanchao;  Yin, Wanchao;  Zhang, Yumin;  Shang, Weijuan;  Wang, Zhen
收藏  |  浏览/下载：112/0  |  提交时间：2021/11/04
Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:  Su, Haixia;  Yao, Sheng;  Zhao, Wenfeng;  Zhang, Yumin;  Liu, Jia
收藏  |  浏览/下载：33/0  |  提交时间：2021/08/17
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang
收藏  |  浏览/下载：87/0  |  提交时间：2021/08/17
One step stereoselective synthesis of oxazoline-fused saccharides and their conversion into the corresponding 1,2-cis glycosylamines bearing various protected groups 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 7, 页码: 1580-1588
作者:  Dong, Sanfeng;  Zhao, Yitian;  Shi, Yulong;  Xu, Zhijian;  Shen, Jingshan
收藏  |  浏览/下载：16/0  |  提交时间：2021/05/24
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文
SCIENCE, 2020, 卷号: 368, 期号: 6498, 页码: 1499-+
作者:  Yin, Wanchao;  Mao, Chunyou;  Luan, Xiaodong;  Shen, Dan-Dan;  Shen, Qingya
收藏  |  浏览/下载：61/0  |  提交时间：2020/12/24
Synthesis of CBD and Its Derivatives Bearing Various C4 '-Side Chains with a Late-Stage Diversification Method 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 85, 期号: 4, 页码: 2704-2715
作者:  Gong, Xudong;  Sun, Changliang;  Abame, Melkamu Alemu;  Shi, Wenqiang;  Xie, Yuanchao
收藏  |  浏览/下载：55/0  |  提交时间：2020/07/01
Synthesis of CBD and Its Derivatives Bearing Various C4 '-Side Chains with a Late-Stage Diversification Method 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 85, 期号: 4, 页码: 2704-2715
作者:  Gong, XD (Gong, Xudong)[ 2,3 ];  Sun, CL (Sun, Changliang)[ 4 ];  Abame, MA (Abame, Melkamu Alemu)[ 1 ];  Shi, WQ (Shi, Wenqiang)[ 1 ];  Xie, YC (Xie, Yuanchao)[ 1 ]
收藏  |  浏览/下载：35/0  |  提交时间：2020/04/16
Metal-free quinolylation of the primary amino groups of amino acid derivatives and peptides with dihydrooxazolo[3,2-a]quinoliniums 期刊论文
GREEN CHEMISTRY, 2019, 卷号: 21, 期号: 15, 页码: 4231-4237
作者:  Liu, Peng;  Li, Bo;  Xi, Mengyu;  Chen, Zhaoqiang;  Sun, Haiguo
收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Zhen;  Jiang, Xiangrui;  Zhang, Xianglei;  Tian, Guanghui;  Yang, Rulei
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01

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