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One-step method to prepare coccinellaseptempunctate-like silver nanoparticles for high sensitivity SERS detection 期刊论文
SURFACES AND INTERFACES, 2022, 卷号: 35, 页码: 8
作者:  Wang, Siyu;  Xi, Shichuan;  Pan, Ruhao;  Yang, Yang;  Luan, Zhendong
收藏  |  浏览/下载：22/0  |  提交时间：2023/01/04
基于效能视角的图书馆营销评估方法体系构建 期刊论文
图书馆学研究, 2018, 期号: 23, 页码: 20-29
作者:  张汝昊;  吴鸣
收藏  |  浏览/下载：16/0  |  提交时间：2019/03/07
p53 induces miR199a-3p to suppress SOCS7 for STAT3 activation and renal fibrosis in UUO 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 43409
作者:  Yang, Ruhao;  Xu, Xuan;  Li, Huiling;  Chen, Jinwen;  Xiang, Xudong
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03
p53 induces miR199a-3p to suppress SOCS7 for STAT3 activation and renal fibrosis in UUO 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:  Yang, Ruhao;  Xu, Xuan;  Li, Huiling;  Chen, Jinwen;  Xiang, Xudong
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/05
上海市高校学生性短信收发现状及影响因素分析 期刊论文
中国学校卫生, 2016, 卷号: 37, 期号: 9
作者:  闵敏;  周汝琳;  沈洁;  廉启国;  张焕玲
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/05
上海市高校学生性短信收发现状及影响因素分析 期刊论文
中国学校卫生, 2016, 期号: 9
作者:  闵敏;  周汝琳;  沈洁;  廉启国;  张焕玲
收藏  |  浏览/下载：1/0  |  提交时间：2019/12/06
Paclitaxel attenuates renal interstitial fibroblast activation and interstitial fibrosis by inhibiting STAT3 signaling 期刊论文
Drug Design, Development and Therapy, 2015, 卷号: 9, 页码: 2139-2148
作者:  Zhang, Lei;  Xu, Xuan;  Yang, Ruhao;  Chen, Jingwen;  Wang, Shixuan
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/03
Recent studies have demonstrated that paclitaxel might inhibit renal fibrosis. However  the underlying molecular mechanism remains unclear. In this study  we hypothesized that low-dose paclitaxel may block the STAT3 (signal transducer and activator of transcription 3) signaling to attenuate fibrosis in a mouse model with unilateral ureteral obstruction. Both NRK-49F cells and mice with unilateral ureteral obstruction were treated with paclitaxel. The results showed that paclitaxel treatment resulted in a dose- and time-dependent decrease in tyrosine-phosphorylated STAT3  and inhibited the expression of fibronectin  alpha-smooth muscle actin (α-SMA)  and collagen I in cultured NRK-49F cells. S3I-201  an STAT3 inhibitor  also suppressed the expression of fibronectin  α-SMA  and collagen I in cultured NRK-49F cells. Mechanistically  paclitaxel treatment blocked the STAT3 activity by disrupting the association of STAT3 with tubulin and inhibiting STAT3 nucleus translocation. Furthermore  paclitaxel also ameliorated renal fibrosis by down-regulating the expression of fibronectin  α-SMA  and collagen I  and suppressed the infiltration of macrophages and production of TNF-α  IL-1β  TGF-β  and ICAM-1 (intercellular adhesion molecule 1) by inhibition of STAT3 activity in obstructive nephropathy. These results suggest that paclitaxel may block the STAT3 activity by disrupting the association of STAT3 with tubulin and inhibiting STAT3 nucleus translocation  consequently leading to the suppression of renal interstitial fibroblast activation and the development of renal fibrosis  and inhibition of proinflammatory cytokine production.  
Paclitaxel: new uses for an old drug 期刊论文
Drug Design, Development and Therapy, 2014, 卷号: 8, 页码: 279-284
作者:  Zhang, Dongshan;  Yang, Ruhao;  Wang, Shixuan;  Dong, Zheng*
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03
Vertical distribution of water-soluble, sea salt, and dust aerosols in the planetary boundary layer estimated from two-wavelength backscatter and one-wavelength polarization lidar measurements in Guangzhou and Beijing, China 期刊论文
atmospheric research, 2010
Nishizawa, Tomoaki; Sugimoto, Nobuo; Matsui, Ichiro; Shimizu, Atsushi; Liu, Xingang; Zhang, Yuanhang; Li, Ruhao; Liu, Jun
收藏  |  浏览/下载：1/0  |  提交时间：2015/11/12
Continuous Observations of Aerosol Profiles with a Two-Wavelength Mie-Scattering Lidar in Guangzhou in PRD2006 期刊论文
journal of applied meteorology and climatology, 2009
Sugimoto, Nobuo; Nishizawa, Tomoaki; Liu, Xingang; Matsui, Ichiro; Shimizu, Atsushi; Zhang, Yuanhang; Kim, Young J.; Li, Ruhao; Liu, Jun
收藏  |  浏览/下载：1/0  |  提交时间：2015/11/16

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