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CORC

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Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
作者:  Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping
收藏  |  浏览/下载：31/0  |  提交时间：2019/11/27
Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models 期刊论文
CANCER LETTERS, 2019, 页码: 105-114
作者:  Lu, Tingting;  Chen, Cheng;  Wang, Aoli;  Jiang, Zongru;  Qi, Ziping
收藏  |  浏览/下载：16/0  |  提交时间：2020/07/14
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/11
Salviachinensines A-F, Antiproliferative Phenolic Derivatives from the Chinese Medicinal Plant Salvia chinensis 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 11, 页码: 2531-2538
作者:  Wang, Qi;  Hu, Zhenquan;  Li, Xixiang;  Wang, Aoli;  Wu, Hong
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/25
Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916
作者:  Wang, Beilei;  Wu, Jiaxin;  Wu, Yun;  Chen, Cheng;  Zou, Fengming
收藏  |  浏览/下载：69/0  |  提交时间：2019/12/25
Two new tricycloalternarenes from Hawaiian endophytic fungus Didymella sp FT433 期刊论文
TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 36, 页码: 3381-3383
作者:  Li, Chunshun;  Hu, Zhenquan;  Liu, Qingsong;  Wu, Xiaohua;  Cao, Shugeng
收藏  |  浏览/下载：32/0  |  提交时间：2019/11/11
Salviachinensines A–F, Antiproliferative Phenolic Derivatives from the Chinese Medicinal Plant Salvia chinensis 期刊论文
Journal of Natural Products, 2018, 卷号: Vol.81 No.11, 页码: 2531-2538
作者:  Xixiang Li;  Qi Wang;  Zhenquan Hu;  Qingsong Liu;  Jing Liu
收藏  |  浏览/下载：4/0  |  提交时间：2019/04/24
Discovery of 4--4-amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: Vol.158, 页码: 896-916
作者:  Wang, Beilei;  Wu, Yun;  Liu, Qingwang;  Jiang, Zongru;  Wu, Jiaxin
收藏  |  浏览/下载：8/0  |  提交时间：2019/04/24
Salviachinensines A-F, Antiproliferative Phenolic Derivatives from the Chinese Medicinal Plant Salvia chinensis 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: Vol.81 No.11, 页码: 2531-2538
作者:  Cao, Shugeng;  Liu, Qingsong;  Wu, Hong;  Hu, Zhenquan;  Wang, Qi
收藏  |  浏览/下载：3/0  |  提交时间：2019/04/24
Salviachinensines A-F, Antiproliferative Phenolic Derivatives from the Chinese Medicinal Plant Salvia chinensis. 期刊论文
Journal of natural products, 2018
作者:  Cao Shugeng;  Wang Qi;  Li Xixiang
收藏  |  浏览/下载：2/0  |  提交时间：2019/04/24

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