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上海药物研究所 [24]
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期刊论文 [49]
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Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:
Fan, Shijie
;
Yue, Liyan
;
Wan, Wei
;
Zhang, Yuanyuan
;
Zhang, Bidong
收藏
  |  
浏览/下载:91/0
  |  
提交时间:2021/12/16
covalent modification
probes
proteome
LC3
post-translational modification
Aristolochic acid I induces impairment in spermatogonial stem cell in rodents (vol 10, pg 436, 2021)
期刊论文
TOXICOLOGY RESEARCH, 2021, 卷号: 10, 期号: 4, 页码: 959-959
作者:
Liu, Yongzhen
;
He, Xiang
;
Wang, Yuli
;
Zhou, Houzu
;
Zhang, Yuan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/11/04
DNA-encoded C-H functionality via photoredox-mediated hydrogen atom transformation catalysis
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 42, 页码: 4
作者:
Shan, Jinming
;
Ling, Xing
;
Liu, JiaXiang
;
Wang, Xuan
;
Lu, Xiaojie
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2021/08/17
Photoredox
Hydrogen atom transfer
N-Boc saturated heterocycle
DNA Encoded Library (DEL)
miR-34a-5p regulates PINK1-mediated mitophagy via multiple modes
期刊论文
LIFE SCIENCES, 2021, 卷号: 276, 页码: 13
作者:
Tai, Yusi
;
Pu, Mei
;
Yuan, Luyang
;
Guo, Huijie
;
Qiao, Junwen
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/08/17
Mitophagy
PINK1
miR-34a-5p
CDS
Non-seed region
Simultaneous determination of forsythin and its major metabolites in human plasma via liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7
作者:
Pan, Lu-lu
;
Chen, Tao
;
Hui, Min
;
Wang, Shuo
;
Fu, Li
收藏
  |  
浏览/下载:136/0
  |  
提交时间:2021/05/24
LC-MS/MS
Forsythin
Aglycone glucuronide
Aglycone sulfate
Pharmacokinetics
Phase-Transition-Induced VO2 Thin Film IR Photodetector and Threshold Switching Selector for Optical Neural Network Applications
期刊论文
ADVANCED ELECTRONIC MATERIALS, 2021
作者:
Zhou, Xi
;
Zhao, Liang
;
Zhen, Weili
;
Lin, Yinyue
;
Wang, Chunlin
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/05/06
neuromorphic computing
optical neural networks
photodetectors
threshold switching
vanadium dioxide
Diversified strategy for the synthesis of DNA-encoded oxindole libraries
期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 12, 期号: 8, 页码: 2841-2847
作者:
Wang, Xuan
;
Liu, Jiaxiang
;
Yan, Ziqin
;
Liu, Xiaohong
;
Liu, Sixiu
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:
Zhang, Rui
;
Li, Heng
;
Zhang, Xianglei
;
Li, Jian
;
Su, Haixia
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
PDE4 inhibitors
Tetrahydroisoquinoline
Antipsoriasis
miR-552-3p modulates transcriptional activities of FXR and LXR to ameliorate hepatic glycolipid metabolism disorder
期刊论文
JOURNAL OF HEPATOLOGY, 2021, 卷号: 74, 期号: 1, 页码: 8-19
作者:
Fan, Lei
;
Lai, Rongtao
;
Ma, Ningning
;
Dong, Yunxia
;
Li, Yu
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
miR-552-3p
Transcriptional gene regulation
Intranuclear miRNAs
Glycolipid metabolic disease
NR1 subfamily
Palladium-mediated Suzuki-Miyaura Cross-Coupling Reaction of Potassium Boc-protected aminomethyltrifluoroborate with DNA-Conjugated aryl bromides for DNA-Encoded chemical library synthesis
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 卷号: 533, 期号: 2, 页码: 209-214
作者:
Qu, Yi
;
Liu, Sixiu
;
Wen, Huanan
;
Xu, Yanfen
;
An, Yulong
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2020/12/24
DNA Encoded chemistry
Suzuki-miyaura cross-coupling
Potassium trifluoroborates
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