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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 110, 页码: 51-61
作者:
Li, Xin
;
Yang, Changyong
;
Wan, Hong
;
Zhang, Ge
;
Feng, Jun
收藏
  |  
浏览/下载:143/0
  |  
提交时间:2019/01/08
Pyrotinib
HER2-postive breast cancer
Irreversible EGFR/HER2 dual tyrosine kinase
inhibitor
Preclinical
Clinical
Safety
Drug metabolism
Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry
期刊论文
Journal of chromatography b-analytical technologies in the biomedical and life sciences, 2016, 卷号: 1033, 页码: 117-127
作者:
Zhu, Yunting
;
Li, Liang
;
Zhang, Ge
;
Wan, Hong
;
Yang, Changyong
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/05/09
Pyrotinib
Uplc/q-tof ms
Metabolism
Human
Cyp3a4
Drug-drug interaction
Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1033, 页码: 117-127
作者:
Zhu, Yunting
;
Li, Liang
;
Zhang, Ge
;
Wan, Hong
;
Yang, Changyong
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Pyrotinib
UPLC/Q-TOF MS
Metabolism
Human
CYP3A4
Drug-drug interaction
Efficacy and safety of serial atorvastatin load in Chinese patients undergoing elective percutaneous coronary intervention: results of the ISCAP (Intensive Statin Therapy for Chinese Patients with Coronary Artery Disease Undergoing Percutaneous Coronary Intervention) randomized controlled trial
期刊论文
EUROPEAN HEART JOURNAL SUPPLEMENTS, 2015, 卷号: 17, 期号: B
作者:
Zheng, Bo
;
Jiang, Jie
;
Liu, Huiliang
;
Zhang, Jun
;
Li, Hui
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
Atorvastatin
Percutaneous coronary intervention
Periprocedural myocardial infarction
Efficacy and safety of serial atorvastatin load in Chinese patients undergoing elective percutaneous coronary intervention: results of the ISCAP (Intensive Statin Therapy for Chinese Patients with Coronary Artery Disease Undergoing Percutaneous Coronary Intervention) randomized controlled trial
期刊论文
EUROPEAN HEART JOURNAL SUPPLEMENTS, 2015, 卷号: 17, 期号: B
作者:
Zheng, Bo
;
Jiang, Jie
;
Liu, Huiliang
;
Zhang, Jun
;
Li, Hui
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/19
Atorvastatin
Percutaneous coronary intervention
Periprocedural myocardial infarction
Efficacy and safety of serial atorvastatin load in Chinese patients undergoing elective percutaneous coronary intervention: results of the ISCAP (Intensive Statin Therapy for Chinese Patients with Coronary Artery Disease Undergoing Percutaneous Coronary Intervention) randomized controlled trial
期刊论文
EUROPEAN HEART JOURNAL SUPPLEMENTS, 2015, 卷号: 17, 期号: B
作者:
Zheng, Bo
;
Jiang, Jie
;
Liu, Huiliang
;
Zhang, Jun
;
Li, Hui
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Atorvastatin
Percutaneous coronary intervention
Periprocedural myocardial infarction
Association between Changing Mortality of Digestive Tract Cancers and Water Pollution: A Case Study in the Huai River Basin, China
期刊论文
2015, 卷号: 12, 期号: 1, 页码: 214-226
作者:
Ren, Hongyan
;
Wan, Xia
;
Yang, Fei
;
Shi, Xiaoming
;
Xu, Jianwei
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/13
increasing mortality
digestive tract cancers
water pollution
drinking water safety
Huai River Basin
Acetylcholinesterase, a Key Prognostic Predictor for Hepatocellular Carcinoma, Suppresses Cell Growth and Induces Chemosensitization
期刊论文
HEPATOLOGY, 2011, 卷号: 53, 期号: 2
作者:
Zhao, Yingjun
;
Wang, Xiaoying
;
Wang, Tao
;
Hu, Xin
;
Hui, Xin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
LC-MS/MS determination of tizanidine in human plasma
期刊论文
Chinese Journal of Pharmaceutical Analysis, 2011, 卷号: 31, 期号: 8, 页码: 1435-1439
作者:
WAN Mimi
;
ZHAN Yan
;
CHEN Xiaoyan
;
ZHANG Yifan
;
ZHONG Dafang
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
tizanidine
imidazoline derivative
liquid chromatography
mass spectrometry
pharmacokinetics
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