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科研机构
上海药物研究所 [37]
山东大学 [6]
昆明植物研究所 [2]
华南理工大学 [2]
大连化学物理研究所 [1]
中国科学院大学 [1]
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期刊论文 [55]
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Idarubicin Stimulates Cell Cycle- and TET2-Dependent Oxidation of DNA 5-Methylcytosine in Cancer Cells
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 5, 页码: 861-868
作者:
Zhong, Shangwei
;
Li, Cuiping
;
Han, Xiao
;
Li, Xiangjun
;
Yang, Yun-Gui
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/10/21
Antiproliferative and Enzyme Docking Analysis of Engleromycin from Engleromyces goetzei
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 9
作者:
Guo, Mingquan
;
Ma, Hong
;
Chen, Guilin
;
Zhang, Yongli
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/03/05
Engleromyces goetzei
engleromycin
antiproliferative activities
molecular docking
Synthetic optimization of ellipticine and antitumor activity of novel hexacyclic derivatives of ellipticine
期刊论文
2019
作者:
Lin Jingjing
;
Tang Mei
;
Zhao Ru
;
Du Qianqian
;
Shen Longying
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/01/03
Antitumor activity
Ellipticine
Hexacyclic derivatives
Synthesis
Topoisomerase IIα inhibitor
New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264
作者:
Tian, Qian-Ting
;
Ding, Chun-Yong
;
Song, Shan-Shan
;
Wang, Ying-Qing
;
Zhang, Ao
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Tanshinone-1
S222
S439
Anticancer targets
DNA topoisomerases
P53
Amexanthomycins A-J, pentangular polyphenols produced by Amycolatopsis mediterranei S699 Delta rifA
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2018, 卷号: 102, 期号: 2, 页码: 689-702
作者:
Li, Xiaomei
;
Wu, Xingkang
;
Zhu, Jing
;
Shen, Yuemao
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/11
Amycolatopsis mediterranei S699
Pentangular polyphenols
Topoisomerase
II alpha inhibitor
min-PKS
Synthesis and biological research of novel azaacridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 页码: 3437-3446
作者:
Li, Dan[1,2,3]
;
Yuan, Zigao[1,2,3]
;
Chen, Shaopeng[2,3]
;
Zhang, Cunlong[3]
;
Song, Lu[1,2,3]
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/04/24
Azaacridine derivatives
Molecular docking
DNA binding
Topoisomerase II inhibitor
Antiproliferative activity
Triptolide Induces Cell Killing in Multidrug-Resistant Tumor Cells via CDK7/RPB1 Rather than XPB or p44
期刊论文
MOLECULAR CANCER THERAPEUTICS, 2016, 卷号: 15, 期号: 7, 页码: 1495-1503
作者:
Yi, Jun-Mei
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Zhou, Hu
;
Wang, Ying-Qing
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Synthesis and antiproliferative activity of 9-benzylamino-6-chloro-2-methoxy-acridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 116, 页码: 59-70
作者:
Zhang, Wei[1,2,3]
;
Zhang, Bin[3]
;
Zhang, Wei[1,2,3]
;
Yang, Ti[1]
;
Wang, Ning[1,2]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/04/24
Acridine derivatives
Topoisomerase II inhibitor
Antiproliferative activity
DNA damage
Millepachine, a potential topoisomerase II inhibitor induces apoptosis via activation of NF-κB pathway in ovarian cancer
期刊论文
Oncotarget, 2016, 卷号: Vol.7 No.32, 页码: 52281-52293
作者:
Wu, W.
;
Ma, B.
;
Ye, H.
;
Wang, T.
;
Wang, X.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/02/25
Apoptosis
Millepachine
NF-κB
pathway
Ovarian
cancer
Topoisomerase
II
inhibitor
Design, synthesis, biological evaluation and molecular docking study on peptidomimetic analogues of XK469
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 124, 页码: 311-325
作者:
Xia, Qiao-Hong
;
Hu, Wei
;
Li, Chen
;
Wu, Ji-Feng
;
Yang, Liang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/17
XK469
Quinoxaline peptidomimetic analogues
Hydrophobic chain
Topoisomerase II inhibitor
Antineoplastic agents
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