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上海药物研究所 [7]
心理研究所 [7]
中南大学 [4]
北京大学 [2]
上海神经科学研究所 [2]
昆明动物研究所 [2]
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期刊论文 [29]
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Substantia Nigra Integrity Correlates with Sequential Working Memory in Parkinson's Disease
期刊论文
JOURNAL OF NEUROSCIENCE, 2021, 卷号: 41, 期号: 29, 页码: 6304-6313
作者:
Liu, Wenyue
;
Wang, Changpeng
;
He, Tingting
;
Su, Minghong
;
Lu, Yuan
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2021/10/29
basal ganglia
functional MRI
neuromelanin-sensitive MRI
Parkinson's disease
sequential working memory
substantia nigra
Ultra-High-Resolutionin vitroMRI Study of Age-Related Brain Subcortical Susceptibility Alteration in Rhesus Monkeys at 9.4 T
期刊论文
FRONTIERS IN AGING NEUROSCIENCE, 2020, 卷号: 12
作者:
Wen, Qingqing
;
Yang, Hongyi
;
Li, Jiali
;
Zhang, Jin
;
Tong, Haiyang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/10/26
quantitative susceptibility mapping
iron concentration
brain aging
rhesus monkey
high resolution
9
4 T
Caffeic acid reduces A53T alpha-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease
期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 150, 页码: 14
作者:
Zhang, Yu
;
Wu, Qimei
;
Zhang, Lei
;
Wang, Qing
;
Yang, Zexian
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  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Caffeic acid
A53T
Parkinson's disease
Autophagy
JNK
Phosphorylated a-Synuclein Accumulations and Lewy Body-like Pathology Distributed in Parkinson’s Disease-Related Brain Areas of Aged Rhesus Monkeys Treated with MPTP
期刊论文
NEUROSCIENCE RESEARCH ARTICLE, 2018, 期号: 379, 页码: 302–315
作者:
Baihui Huang
;
Yong Yin
;
Zhengbo Wang
;
Xintian Hu
;
Longjiao Ge
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  |  
浏览/下载:29/0
  |  
提交时间:2018/09/20
Phosphorylated A-synuclein
Parkinson’s Disease
Pathogenesis
Midbrain
Neocortex
Mptp
Prion-like propagation of α-synuclein in the gut-brain axis
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 341-346
作者:
Chen, Ying
;
Shao, Qianhang
;
Yuan, Yu-He*
;
Chen, Nai-Hong*
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  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
CNS
central nervous system
DA
dopamine
DMV
dorsal motor nucleus of the vagus
ENS
enteric nervous system
GI
gastrointestinal
IL-1
interleukin-1
LBs
Lewy bodies
LPS
lipopolysaccharide
LAG3
lymphocyte-activation gene 3
MPTP
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
P301L
mutant Tau
PD
Parkinson's disease
PNS
peripheral nervous system
ROS
reactive oxygen species
SCFA
short chain fatty acids
SN
substantia nigra
TH
Tyrosine hydroxylase
TLR 2
Toll-like receptor 2
TNTs
tunneling nanotubes
α-synuclein
Prion-like
Enteric nervous system
Gut-brain axis
Non-motor symptom
Parkinson’s disease
Amentoflavone protects dopaminergic neurons in MPTP-induced Parkinson's disease model mice through PI3K/Akt and ERK signaling pathways
期刊论文
Toxicology and applied pharmacology, 2017, 卷号: 319, 页码: 80-90
作者:
Cao, Qin
;
Qin, Liyue
;
Huang, Fei
;
Wang, Xiaoshuang
;
Yang, Liu
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Mfn2 protects dopaminergic neurons exposed to paraquat both in vitro and in vivo: Implications for idiopathic Parkinson's disease
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 6, 页码: 1359-1370
作者:
Zhao, Fanpeng
;
Wang, Wenzhang
;
Wang, Chunyu
;
Siedlak, Sandra L.
;
Fujioka, Hisashi
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
DA
dopaminergic
DIV
days in vitro
DLP1
dynamin-like protein 1
4-HNE
4-hydroxynonenal
JNKs
c-Jun N-terminal kinases
MPTP
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
MAP2
microtubule-associated protein-2
Fis1
mitochondrial fission 1
Mff
mitochondrial fission factor
Mfn2
mitofusin 2
MMP
mitochondrial membrane potential
Mfn1/2
mitofusin 1/2
OPA1
optic atrophy 1
PQ
paraquat
PD
Parkinson's disease
ROS
reactive oxygen species
SN
substantia nigra pars compacta
TMRM
tetramethylrhodamine methyl ester
TH
tyrosine hydroxylase
Tg
transgenic
Mitochondrial dynamics
DLP1
Drp1
Mfn2
Paraquat
Parkinson's disease
Neuroprotective effects of lentivirus-mediated cystathionine-beta-synthase overexpression against 6-OHDA-induced parkinson's disease rats
期刊论文
Neuroscience Letters, 2017, 卷号: 657, 页码: 45-52
作者:
Weilan, Yin
;
Weiguo, Yin
;
Baisheng, Huang
;
Lixiang, Wu
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
PD
parkinson's disease
DA
dopaminergic
SN
substantia nigra
H2S
hydrogen sulfide
CBS
cystathionine-beta-synthas
6-OHDA
6-Hydroxydopamine
SOD
superoxide dismutase
GSH-Px
glutathione peroxidase
MDA
mlonic dialdehyde
α-SYN
α-synuclein
AOAA
amino-oxyacetate
TH
tyrosine-hydroxylase
SD
sprayer-daley
Cystathionine-beta-synthase
Hydrogen sulfide
Lentivirus
Overexpression
Neuroprotection
Parkinson’s disease
Elevated hapln2 expression contributes to protein aggregation and neurodegeneration in an animal model of parkinson's disease
期刊论文
Frontiers in aging neuroscience, 2016, 卷号: 8, 页码: 12
作者:
Wang, Qinqin
;
Zhou, Qinbo
;
Zhang, Shuzhen
;
Shao, Wei
;
Yin, Yanqing
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2019/05/09
Hyaluronan and proteoglycan binding link protein 2
Parkinson's disease
Dopaminergic neurons
Ubiquitin-proteasome system
Aggregation
Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease
期刊论文
PROTEIN & CELL, 2016, 卷号: 7, 期号: 2, 页码: 114-129
作者:
Song, Pingping
;
Li, Shanshan
;
Wu, Hao
;
Gao, Ruize
;
Rao, Guanhua
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2016/05/09
parkin
sequestosome1/p62
ubiquitin
substantia nigra
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