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Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1 期刊论文
EXPERIMENTAL NEUROLOGY, 2019, 卷号: 311
作者:  Lu, Mei-Hong;  Ji, Wen-Li;  Xu, De-En;  Yao, Pei-Pei;  Zhao, Xiu-Yun
收藏  |  浏览/下载:22/0  |  提交时间:2019/12/04
Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163
作者:  Li, Yali;  Huang, Taomin;  Lou, Bin;  Ye, Deyong;  Qi, Xiangyu
收藏  |  浏览/下载:29/0  |  提交时间:2019/12/05
Discovery of 4-Benzyloxybenzo[d]isoxazole-3-amine Derivatives as Highly Selective and Orally Efficacious Human Sphingomyelin Synthase 2 Inhibitors that Reduce Chronic Inflammation in db/db Mice 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 18
作者:  Mo, Mingguang;  Yang, Jintong;  Jiang, Xian-Cheng;  Cao, Yu;  Fei, Jinyu
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/05
Chinese hamster ovary-sphingomyelin synthase2 biospecific extraction and liquid chromatography with tandem mass spectrometry analysis for the prediction of bioactive components of Rhizoma Polygoni Cuspidati 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2016, 卷号: 39, 期号: 6
作者:  Dong, Jibin;  Liang, Jianying;  Xue, Ying
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/05
Novel Dual Inhibitors of Secretory Phospholipase A(2) and Sphingomyelin Synthase: Design, Synthesis and Evaluation 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2016, 卷号: 13, 期号: 10
作者:  Gong, Haojun;  Zhou, Lu;  Ye, Deyong;  Gao, Xing;  Li, Yali
收藏  |  浏览/下载:15/0  |  提交时间:2019/12/06
Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors 期刊论文
Bioorg. Med. Chem., 2015, 卷号: 23, 期号: 18, 页码: 6173-6184
作者:  Li YL(李亚莉);  Qi XY(齐翔宇);  Jiang H(蒋慧);  Deng XD(邓小东);  Dong YP(董艳萍)
收藏  |  浏览/下载:41/0  |  提交时间:2016/12/06
Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 18
作者:  Li, Ya-li;  Qi, Xiang-yu;  Jiang, Hui;  Deng, Xiao-dong;  Dong, Yan-ping
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/19
All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity 期刊论文
JOURNAL OF LIPID RESEARCH, 2015, 卷号: 56, 期号: 3
作者:  Ding, Tingbo;  Kabir, Inamul;  Li, Yue;  Lou, Caixia;  Yazdanyar, Amirfarbod
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/19
Prenatal alcohol exposure inducing the apoptosis of mossy cells in hippocampus of SMS2-/- mice 期刊论文
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2015, 卷号: 40, 期号: 3, 页码: 975-982
作者:  Wang, Lai[1];  Wu, Lin[2];  Wang, Xiaoqing[3];  Deng, Jiexin[4];  Ma, Zhanyou[5]
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/23
Identification of small molecule sphingomyelin synthase inhibitors 期刊论文
Eur. J. Med. Chem., 2014, 卷号: 73, 页码: 1-7
作者:  DENG XIAODONG;  LIN FU;  ZHANG YA;  LI YAN;  ZHOU LU
收藏  |  浏览/下载:18/0  |  提交时间:2016/08/30


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