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浏览/检索结果:
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Solubilization, purification, and ligand binding characterization of G protein-coupled receptor SMO in native membrane bilayer using styrene maleic acid copolymer
期刊论文
PEERJ, 2022, 卷号: 10
作者:
Zhu, Lina
;
Zhao, Hongxin
;
Wang, Yizhuo
;
Yu, Chuandi
;
Liu, Juanjuan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/12/23
GPCR
Dissociation constant
Detergents
Styrene maleic acid copolymer nanodiscs
Smoothened receptors
NMR
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:
Liu, Xiaohua
;
Zhang, Yu
;
Li, Yalei
;
Wang, Juan
;
Ding, Huaqian
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
Medulloblastoma
Hedgehog signaling
pathway
Drug resistance
GLI
BRD4
Constructing effective energy functions for protein structure prediction through broadening attraction-basin and reverse Monte Carlo sampling
期刊论文
BMC BIOINFORMATICS, 2019, 卷号: 20, 页码: 10
作者:
Zhang, Haicang
;
Wang, Chao
;
Bu, Dongbo
;
Zheng, Wei-Mou
;
Sun, Shiwei
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2019/08/16
Protein structure prediction
Energy function
Attraction-basin
Reverse Monte Carlo sampling
Monte Carlo search
Linear program
miR-370 inhibits the angiogenic activity of endothelial cells by targeting smoothened (SMO) and bone morphogenetic protein (BMP)-2
期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 6
作者:
Gu, Yuan
;
Becker, Vivien
;
Zhao, Yingjun
;
Menger, Michael D.
;
Laschke, Matthias W.
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  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
miRNA
angiogenesis
proliferation
migration
tube formation
Constructing effective energy functions for protein structure prediction through broadening attraction-basin and reverse Monte Carlo sampling
期刊论文
BMC BIOINFORMATICS, 2019, 卷号: 20, 页码: 135
作者:
Wang, C
;
Wei, Y
;
Zhang, HC
;
Kong, LP
;
Sun, SW
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  |  
浏览/下载:0/0
  |  
提交时间:2019/07/19
TERTIARY STRUCTURES
FRAGMENTS
Constructing effective energy functions for protein structure prediction through broadening attraction-basin and reverse Monte Carlo sampling
期刊论文
BMC BIOINFORMATICS, 2019, 卷号: 20, 页码: 135
作者:
Wang, Chao
;
Wei, Yi
;
Zhang, Haicang
;
Kong, Lupeng
;
Sun, Shiwei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/11/26
TERTIARY STRUCTURES
FRAGMENTS
Constructing effective energy functions for protein structure prediction through broadening attraction-basin and reverse Monte Carlo sampling
会议论文
Wuhan, PEOPLES R CHINA, JAN 14-16, 2019
作者:
Wang, C
;
Wei, Y
;
Zhang, HC
;
Kong, LP
;
Sun, SW
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2019/07/24
TERTIARY STRUCTURES
FRAGMENTS
Overcoming the emerging drug resistance of smoothened: an overview of small-molecule SMO antagonists with antiresistance activity
期刊论文
FUTURE MEDICINAL CHEMISTRY, 2018, 卷号: 10, 期号: 24, 页码: 2855-2875
作者:
Zhang, Heng
;
Sun, Zhijun
;
Liu, Zhaopeng
;
Song, Chun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
cancer
drug resistance
hedgehog signaling pathway
smoothened
antagonist
smoothened protein
Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand
期刊论文
NATURE COMMUNICATIONS, 2017, 卷号: 8
作者:
Zhang, Xianjun
;
Zhao, Fei
;
Wu, Yiran
;
Yang, Jun
;
Han, Gye Won
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase
期刊论文
PLOS BIOLOGY, 2016, 卷号: 14, 期号: 6, 页码: e1002481
作者:
Li SX
;
Li S
;
Han YH
;
Tong C
;
Wang B
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2016/06/14
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