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Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng
收藏  |  浏览/下载:24/0  |  提交时间:2022/12/23
Recent Updates on The Role of Galanin and Its Receptors in Regulating Depressive Symptoms 期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2022, 卷号: 49, 期号: 1, 页码: 113-125
作者:  Xue Bing;  Ma Yin-Yan;  Liang Jing;  Li Yong-Hui;  Zhang Jian-Jun
收藏  |  浏览/下载:50/0  |  提交时间:2022/03/28
Amygdala dynorphin/kappa opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zan, Gui-ying;  Sun, Xiang;  Wang, Yu-jun;  Liu, Rui;  Wang, Chen-yao
收藏  |  浏览/下载:29/0  |  提交时间:2021/08/17
Discovery of 1,5-Dihydro-4H-imidazol-4-one Derivatives as Potent, Selective Antagonists of CXC Chemokine Receptor 2 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 5, 页码: 836-845
作者:  Che, Jinxin;  Wang, Zhilong;  Shen, Zheyuan;  Zhuang, Weihao;  Ying, Huazhou
收藏  |  浏览/下载:65/0  |  提交时间:2021/08/17
Structural basis for ligand recognition of the neuropeptide Y Y-2 receptor 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 9
作者:  Tang, Tingting;  Hartig, Christin;  Chen, Qiuru;  Zhao, Wenli;  Kaiser, Anette
收藏  |  浏览/下载:41/0  |  提交时间:2021/05/24
甘丙肽对抑郁症状的调控作用及其机制的研究进展 期刊论文
生物化学与生物物理进展, 2021, 页码: 15
作者:  薛冰;  马寅燕;  梁璟;  李勇辉;  张建军
收藏  |  浏览/下载:39/0  |  提交时间:2021/12/03
Update of P2Y receptor pharmacology: IUPHAR Review 27 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 11, 页码: 2413-2433
作者:  Jacobson, Kenneth A.;  Delicado, Esmerilda G.;  Gachet, Christian;  Kennedy, Charles;  von Kuegelgen, Ivar
收藏  |  浏览/下载:74/0  |  提交时间:2020/07/01
How Does Agonist and Antagonist Binding Lead to Different Conformational Ensemble Equilibria of the kappa-Opioid Receptor: Insight from Long-Time Gaussian Accelerated Molecular Dynamics Simulation 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 3, 页码: 1575-1584
作者:  An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Zhou, Shuangyan;  Shi, Danfeng
收藏  |  浏览/下载:58/0  |  提交时间:2019/11/10
Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands 期刊论文
CHEMMEDCHEM, 2018, 卷号: 13, 期号: 22, 页码: 2455-2463
作者:  Qian, Hai-Yan;  Wang, Zhi-Long;  Chen, Li-Li;  Pan, You-Lu;  Xie, Xiao-Yu
收藏  |  浏览/下载:95/0  |  提交时间:2019/01/08
7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14, 页码: 4254-4263
作者:  Sun, Hui-jiao;  Wang, Yu-hua;  Yuan, Cong-min;  Kong, Ling-hui;  Xu, Xue-jun
收藏  |  浏览/下载:85/0  |  提交时间:2019/01/08


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