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上海药物研究所 [11]
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期刊论文 [28]
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Comprehensive screening and separation of cyclooxygenase-2 inhibitors from Pterocephalus hookeri by affinity solid-phase extraction coupled with preparative high-performance liquid chromatography
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1183
作者:
Zhu, Yunhe
;
Wang, Weidong
;
Liu, Zenggen
;
Jiang, Sirong
;
Tao, Yanduo
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/11/18
Pterocephalus hookeri
Cyclooxygenase-2 inhibitors
Affinity solid-phase extraction
Preparative HPLC
Target separation
Celecoxib aggravates atherogenesis and upregulates leukotrienes in ApoE mice and lipopolysaccharide-stimulated RAW264.7 macrophages
期刊论文
Atherosclerosis, 2019
作者:
Yimin Pang
;
Lu Gan
;
Xianzhe Wang
;
Qi Su
;
Cong Liang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/17
Atherosclerosis
COX-2-selective inhibitors
Cyclooxygenase-2
5-Lipoxygenase
Leukotrienes
ApoE-/- mice
RAW264.7 macrophages
Synthesis of phenylpiperazine derivatives of 1,4-benzodioxan as selective COX-2 inhibitors and anti-inflammatory agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 21, 页码: 5626-5632
作者:
Sun, Juan
;
Wang, Su
;
Sheng, Gui-Hua
;
Lian, Zhi-Min
;
Liu, Han-Yu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/16
Anti-inflammatory scaffold
Cyclooxygenase-2
1,4-Benzodioxan
Phenylpiperazine
Network Meta-Analysis Comparing Relatively Selective COX-2 Inhibitors Versus Coxibs for the Prevention of NSAID-Induced Gastrointestinal Injury
期刊论文
MEDICINE, 2015, 卷号: 94, 期号: 40
作者:
Yang, M
;
Wang, HT
;
Zhao, M
;
Meng, WB
;
Ou, JQ
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  |  
浏览/下载:4/0
  |  
提交时间:2017/01/09
Celecoxib inhibits the lytic activation of kaposi's sarcoma-associated herpesvirus through down-regulation of rta expression by inhibiting the activation of p38 mapk
期刊论文
Viruses-basel, 2015, 卷号: 7, 期号: 5, 页码: 2268-2287
作者:
Chen, Jungang
;
Jiang, Liangyu
;
Lan, Ke
;
Chen, Xulin
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  |  
浏览/下载:24/0
  |  
提交时间:2019/05/09
Synthesis of Deuterated Benzopyran Derivatives as Selective COX-2 Inhibitors with Improved Pharmacokinetic Properties
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 5, 期号: 10, 页码: 1162-1166
作者:
Lu, Xin
;
Lu, Yongzhi
;
Wen, Dingsheng
;
Bai, Yang
;
Liu, Xiaorong
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2018/12/13
Synthesis of Deuterated Benzopyran Derivatives as Selective COX-2 Inhibitors with Improved Pharmacokinetic Properties
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 5, 期号: 10, 页码: 1162-1166
Zhang, Yanmei
;
Tortorella, Micky D.
;
Wang, Yican
;
Liu, Jianqi
;
Tu, Zhengchao
;
Liu, Xiaorong
;
Bai, Yang
;
Wen, Dingsheng
;
Lu, Xin
;
Lu, Yongzhi
;
Talley, John J.
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2016/12/16
A novel anti-rheumatic drug, iguratimod for RA - an initial clinical trial
期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 页码: 41-42
作者:
Xiao, Feng
;
Zhang, Ling-ling
;
Wei, Wei
;
Xu, Jian-hua
;
Li, Xing-fu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
iguratimod
rheumatoid arthritis
selective COX-2 inhibitors
clinical
trial
A novel anti-rheumatic drug,iguratimod for RA-an initial clinical trial
会议论文
作者:
Feng XIAO
;
Ling-ling ZHANG
;
Wei WEI
;
Jian-hua XU
;
Xing-fu LI
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/31
iguratimod
rheumatoid arthritis
selective COX-2 inhibitors
clinical trial
Design, Synthesis and Biological Evaluation of 2-(2-Aryl-morpholino-4-yl)ethyl Esters of Indomethacin as Potential Cyclooxygenase-2 (COX-2) Inhibitors
期刊论文
Chinese Journal of Chemistry, 2012, 卷号: Vol.30 No.6, 页码: 1339-1344
作者:
Shi, L
;
Hu, AX
;
Xu, JP
;
Jiang, YP
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/05
indomethacin
2-(2-arylmorpholino-4-yl)ethanol
synthesis
COX-2 selective inhibition
antioxidant
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