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期刊论文 [37]
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Diterpenoids from Euphorbia royleana reverse P-glycoprotein-mediated multidrug resistance in cancer cells
期刊论文
PHYTOCHEMISTRY, 2020, 卷号: 176, 页码: -
作者:
Shaker, Sharpkate
;
Sang, Jun
;
Yan, Xue-Long
;
Fan, Run-Zhu
;
Tang, Gui-Hua
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/08/07
INGOL
LATEX
ESTERS
PLANTS
Network Pharmacology and Reverse Molecular Docking-Based Prediction of the Molecular Targets and Pathways for Avicularin Against Cancer
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2019, 卷号: 22, 页码: 4-12
作者:
Duan, Chaohui
;
Li, Yang
;
Dong, Xiaorui
;
Xu, Weibin
;
Ma, Yingli
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  |  
浏览/下载:16/0
  |  
提交时间:2019/12/02
Avicularin
molecular mechanism
MAPK signaling pathway
network pharmacology
reverse molecular docking
molecular targets
H6, a novel hederagenin derivative, reverses multidrug resistance in vitro and in vivo
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018, 卷号: 341, 页码: 98-105
作者:
Yang, Yanting
;
Guan, Daokun
;
Lei, Lei
;
Lu, Jing
;
Liu, Jia Qi
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  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
alpha-Hederagenin
H6
Multidrug resistance
P-glycoprotein
Molecular docking
Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345
作者:
Mao, Fei
;
Wang, Huan
;
Ni, Wei
;
Zheng, Xinyu
;
Wang, Manjiong
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  |  
浏览/下载:58/0
  |  
提交时间:2019/01/08
Alzheimer's disease
drug repositioning
dual-target inhibitor
AChE inhibition
PDE5 inhibition
Reversal of multidrug resistance by Marsdenia tenacissima and its main active ingredients polyoxypregnanes
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2017, 卷号: 203, 页码: 110-119
作者:
To, Kenneth K. W.
;
Wu, Xu
;
Yin, Chun
;
Chai, Stella
;
Yao, Sheng
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  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08
ABCG2
Multidrug resistance
Marsdenia tenacissima
MRP1
P-glycoprotein
Polyoxypregnane compounds
Structural modifications of diarylpyrimidines (DAPYs) as HIV-1 NNRTIs: Synthesis, anti-HIV activities and SAR
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 8, 页码: 2491-2497
作者:
Lu, Huan-Huan
;
Xue, Ping
;
Zhu, Yuan-Yuan
;
Ju, Xiu-Lian
;
Zheng, Xiao-Jiao
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  |  
浏览/下载:15/0
  |  
提交时间:2019/09/25
AIDS
Anti-HIV
Diarylpyrimidines
Nonnucleoside reverse transcriptase
inhibitors
SAR
Role of c-di-GMP in anammox aggregation and systematic analysis of its turnover protein in Candidatus Jettenia caeni
期刊论文
WATER RESEARCH, 2017
Guo, Yongzhao
;
Liu, Sitong
;
Tang, Xi
;
Yang, Fenglin
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  |  
浏览/下载:3/0
  |  
提交时间:2017/12/03
Anammox
c-di-GMP
Nitrogen removal
Bacteria aggregation
PSEUDOMONAS-AERUGINOSA
RESPONSE REGULATOR
BIOFILM FORMATION
GENE-EXPRESSION
BACTERIA
PHOSPHODIESTERASE
DOMAIN
IDENTIFICATION
BIOSYNTHESIS
OXIDATION
Design, synthesis and anti-HIV-1 RT evaluation of 2-(benzyl(4-chlorophenyl)amino)-1-(piperazin-1-yl)ethanone derivatives
期刊论文
Bioorganic & Medicinal Chemistry Letters, 2017, 卷号: 27, 期号: 1, 页码: 61-65
作者:
Chander S
;
Pang W
;
Sankaranarayanan M[*]
;
Ashok P
;
Yang LM
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2016/12/01
Enzymatic assay
Wild strain
Reverse transcriptase
Docking
Cytotoxicity
Identification of Toxic Pyrrolizidine Alkaloids and Their Common Hepatotoxicity Mechanism
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 卷号: 17, 期号: 3
作者:
Yan, Xinmiao
;
Kang, Hong
;
Feng, Jun
;
Yang, Yiyan
;
Tang, Kailin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
hepatotoxicity mechanism
glutathion metabolism
Pyrrolizidine Alkaloids
reverse docking
Pharmacokinetics of 21 active components in focal cerebral ischemic rats after oral administration of the active fraction of Xiao-Xu-Ming decoction
期刊论文
2016, 卷号: 122, 页码: 110-117
作者:
Wang, Caihong
;
Jiar, Zhixin
;
Wang, Zhe
;
Hu, Ting
;
Qin, Hailin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/04
Xiao-Xu-Ming decoction
Pharmacokinetic
Ischemic stroke
Reverse molecular docking
Synergistic effect
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