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Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:
Xie, Hong-Xu
;
Zhang, Juan
;
Li, Yue
;
Zhang, Jin-He
;
Liu, Shan-Kui
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/11/04
Tetrahydrobenzo[b]thiophen-2-yl)urea
alpha-Glucosidase inhibitors
Non-competitive inhibitor
Molecular docking
Anti-hyperglycaemic activity
Type 2 diabetes
Local Active Galactic Nuclei with Large Broad-H alpha Variability Reside in Red Galaxies
期刊论文
ASTROPHYSICAL JOURNAL, 2021, 卷号: 915, 期号: 1
作者:
Liu WJ(刘文娟)
;
Lira, Paulina
;
Yao, Su
;
Xu, Dawei
;
Wang, Jing
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  |  
浏览/下载:54/0
  |  
提交时间:2021/07/24
Discovery of 1,5-Dihydro-4H-imidazol-4-one Derivatives as Potent, Selective Antagonists of CXC Chemokine Receptor 2
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 5, 页码: 836-845
作者:
Che, Jinxin
;
Wang, Zhilong
;
Shen, Zheyuan
;
Zhuang, Weihao
;
Ying, Huazhou
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  |  
浏览/下载:64/0
  |  
提交时间:2021/08/17
cancer metastasis
CXCR1
CXCR2
selectivity
antagonist
1,5-dihydro-4H-imidazol-4-one
Location-Aware Real-Time Recommender Systems for Brick-and-Mortar Retailers
期刊论文
INFORMS JOURNAL ON COMPUTING, 2021, 页码: 17
作者:
Zeng, Daniel
;
Liu, Yong
;
Yan, Ping
;
Yang, Yanwu
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  |  
浏览/下载:37/0
  |  
提交时间:2021/12/28
recommender systems
location-aware recommendation
brick-and-mortar stores
Rational design of a near-infrared fluorescence probe for highly selective sensing butyrylcholinesterase (BChE) and its bioimaging applications in living cell
期刊论文
TALANTA, 2020, 卷号: 219, 页码: 10
作者:
Ma, Jianlong
;
Lu, Xiaofeng
;
Zhai, Honglin
;
Li, Qiang
;
Qiao, Li
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  |  
浏览/下载:28/0
  |  
提交时间:2021/12/15
Fluorescent probe
Rational design
Highly selective
Butyrylcholinesterase
DiscoStyle: Multi-level Logistic Ranking for Personalized Image Style Preference Inference
期刊论文
International Journal of Automation and Computing, 2020, 卷号: 17, 期号: 5, 页码: 637-651
作者:
Zhen-Wei He
;
Lei Zhang
;
Fang-Yi Liu
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  |  
浏览/下载:12/0
  |  
提交时间:2021/02/22
Facial preference
feature representation
logistic regression
face recommendation
transfer learning.
STABLE CONSENSUS DECISION MAKING FOR SPATIALLY DISTRIBUTED MULTIAGENT SYSTEMS WITH MULTIPLE LEADERS
期刊论文
SIAM JOURNAL ON CONTROL AND OPTIMIZATION, 2020, 卷号: 58, 期号: 3, 页码: 1626-1651
作者:
Liu, Zhixin
;
Wang, Lin
;
Dong, Daoyi
;
Baras, John S.
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  |  
浏览/下载:4/0
  |  
提交时间:2020/09/23
multiagent systems
leader-follower model
proportion
stable consensus decision
Computational Insight Into the Small Molecule Intervening PD-L1 Dimerization and the Potential Structure-Activity Relationship
期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 15
作者:
Shi, Danfeng
;
An, Xiaoli
;
Bai, Qifeng
;
Bing, Zhitong
;
Zhou, Shuangyan
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  |  
浏览/下载:27/0
  |  
提交时间:2022/01/19
PD-L1
small-molecule inhibitors
molecular dynamics simulation
metadynamics simulation
R-group QSAR
Modulation of Conformational Preferences of Heteroaromatic Ethers and Amides through Protonation and Ionization: Charge Effect
期刊论文
CHEMISTRYOPEN, 2019, 卷号: 8, 期号: 7, 页码: 840-851
作者:
Dai, Wenshuai
;
Zhang, Zhe
;
Du, Yikui
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  |  
浏览/下载:48/0
  |  
提交时间:2019/12/02
conformational modulation
heteroaromatic ethers
heteroaromatic amides
protonation
ionization
Modeling the Parameter Interactions in Ranking SVM with Low-Rank Approximation
期刊论文
IEEE TRANSACTIONS ON KNOWLEDGE AND DATA ENGINEERING, 2019, 卷号: 31, 期号: 6, 页码: 1181-1193
作者:
Guo, Jiafeng
;
Cheng, Xueqi
;
Lan, Yanyan
;
Zeng, Wei
;
Xu, Jun
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  |  
浏览/下载:44/0
  |  
提交时间:2019/08/16
Learning to rank
ranking SVM
parameter interactions
low-rank approximation
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