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化学研究所 [18]
上海药物研究所 [14]
长春应用化学研究所 [8]
大连化学物理研究所 [6]
清华大学 [5]
成都生物研究所 [5]
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期刊论文 [91]
学位论文 [3]
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Novel poly (ADP-ribose) polymerases inhibitor DHC-1 exhibits in vitro and in vivo anticancer activity on BRCA-deficient pancreatic cancer cells
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 147, 页码: 10
作者:
Wu, Xiaochen
;
Li, Qiqi
;
Zhang, Fan
;
Wang, Lijun
;
Wang, Jun
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/04/21
PARP inhibitor
BRCA
Pancreatic cancer
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
作者:
Guo, Chuanlong
;
Zhang, Fan
;
Wu, Xiaochen
;
Yu, Xuemin
;
Wu, Xianggen
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  |  
浏览/下载:32/0
  |  
提交时间:2020/09/23
PARP-1 inhibitor
DNA double-strand breaks
HCC-1937
In vivo
Apoptosis
Ag85b/ESAT6-CFP10 adjuvanted with aluminum/poly-IC effectively protects guinea pigs from latent mycobacterium tuberculosis infection
期刊论文
VACCINE, 2019, 卷号: 37, 期号: 32, 页码: 4477-4484
作者:
Wang, Chunhua
;
Lu, Jinbiao
;
Du, Weixin
;
Wang, Guozhi
;
Li, Xuguang
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  |  
浏览/下载:58/0
  |  
提交时间:2019/10/18
Mycobacterium tuberculosis
Subunit vaccine
Adjuvant
Immunogenicity
Protective efficacy
Latent tuberculosis infection
Discovery of Novel Bromophenol Thiosemicarbazone Hybrids as Potent Selective Inhibitors of Poly(ADP-ribose) Polymerase-1 (PARP-1) for Use in Cancer
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3051-3067
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Li, Xinxue
;
Wang, Shuaiyu
;
Yu, Xuemin
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  |  
浏览/下载:76/0
  |  
提交时间:2019/08/28
The transcriptomic expression of pattern recognition receptors: Insight into molecular recognition of various invading pathogens in Oyster Crassostrea gigas
期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2019, 卷号: 91, 页码: 1-7
作者:
Wang, Lingling
;
Zhang, Huan
;
Wang, Mengqiang
;
Zhou, Zhi
;
Wang, Weilin
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  |  
浏览/下载:65/0
  |  
提交时间:2019/05/15
Bivalve immunity
Pattern recognition receptors
Crassostrea gigas
Transcriptome
RNA-Seq
Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2018, 卷号: 10, 期号: 48, 页码: 41118-41128
作者:
Chen, Wu
;
Yang, Wen
;
Chen, Pengyu
;
Huang, Yongzhuo
;
Li, Feng
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  |  
浏览/下载:97/0
  |  
提交时间:2019/01/08
disulfiram
copper diethyldithiocarbamate
drug resistance
prostate cancer
nanoparticle
drug delivery
paraptosis
Poly p-hydroxybenzyl substituted bibenzyls and phenanthrenes from Bletilla ochracea Schltr with anti-inflammatory and cytotoxic activity
期刊论文
FITOTERAPIA, 2018, 卷号: 129, 页码: 241-248
作者:
Li, Jin-Yu
;
Yang, Liu
;
Hou, Bo
;
Ren, Fu-Cai
;
Yang, Xiao-Bei
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  |  
浏览/下载:28/0
  |  
提交时间:2018/10/07
Bletilla ochracea
Stilbenoids
Bibenzyls
Phenaothrenes
Cytotoxicity
Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 389-403
作者:
Chen, Xuxing
;
Huan, Xiajuan
;
Liu, Qiufeng
;
Wang, Yuqin
;
He, Qian
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
PARP1/2 inhibitor
Benzimidazole
4,5,6,7-Tetrahydrothienopyridine
Co-crystal structure
Isothermal Titration Calorimetry
Plasma-treated poly(ethylene oxide) nanofibers containing tea tree oil/beta-cyclodextrin inclusion complex for antibacterial packaging
期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 179, 页码: 360-369
作者:
Cui, Haiying[1]
;
Bai, Mei[2]
;
Lin, Lin[3]
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/24
TTO/beta-CD-IC
Electrospun nanofibers
Plasma
Escherichia coli O157:H7
Poly IC pretreatment suppresses B cell-mediated lupus-like autoimmunity through induction of Peli1
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 9, 页码: 862-868
作者:
Wang, Yan[1]
;
Yuan, Jia[2]
;
Dai, Dongfang[3]
;
Liu, Junli[4]
;
Xu, Jing[5]
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/24
poly IC
B cell
systemic lupus erythematosus
Peli1
noncanonical NF-kappa B
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