×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [66]
昆明医科大学 [47]
厦门大学 [30]
中国医学科学院 北... [24]
广州生物医药与健康... [16]
复旦大学上海医学院 [15]
更多...
内容类型
期刊论文 [289]
学位论文 [20]
会议论文 [4]
SCI/SSCI论文 [3]
其他 [1]
发表日期
2021 [4]
2020 [4]
2019 [13]
2018 [23]
2017 [28]
2016 [30]
更多...
学科主题
Pharmacol... [10]
Chemistry [5]
Immunology [5]
Microbiolo... [4]
生物化学与分子生物学 [4]
Biochemist... [3]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共317条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities
期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2022, 卷号: 65, 期号: 6, 页码: 1123-1145
作者:
Luo, Lu
;
Yang, Jun
;
Wang, Cheng
;
Wu, Jie
;
Li, Yafang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/07
natural product
infectious pathogen
drug discovery
drug development
in silico analysis
Picomolar antimalarial agent from a Chinese medicinal plant
期刊论文
SCIENCE CHINA-CHEMISTRY, 2021, 页码: 5
作者:
Zhou, Bin
;
Zimbres, Flavia M.
;
Butler, Joshua H.
;
Xu, Cheng-Hui
;
Haney, Reagan S.
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2021/12/01
medicinal plants
dimeric sesquiterpenoids
antimalarial agent
structure-activity relationship
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439
期刊论文
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:
Shackleford, David M.
;
Chiu, Francis C. K.
;
Katneni, Kasiram
;
Blundell, Scott
;
McLaren, Jenna
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/11/04
OZ439 (artefenomel)
malaria
metabolite identification
cytochrome P450 metabolism
cytochrome P450 inhibition
time-dependent inhibition
Full-Length Transcriptome Analysis of Plasmodium falciparum by Single-Molecule Long-Read Sequencing
期刊论文
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2021, 卷号: 11, 页码: 11
作者:
Yang, Mengquan
;
Shang, Xiaomin
;
Zhou, Yiqing
;
Wang, Changhong
;
Wei, Guiying
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2021/05/24
Plasmodium falciparum
small protein
long non-coding RNA
alternative splicing
full-length RNA-seq
In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues
期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 卷号: 65, 期号: 2, 页码: 11
作者:
Uche, Fidelia Ijeoma
;
Guo, Xiaozhen
;
Okokon, Jude
;
Ullah, Imran
;
Horrocks, Paul
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
malaria
Plasmodium falciparum
Plasmodium berghei
bisbenzylisoquinoline alkaloids
cycleanine
metabolism
in vivo activity
antimalarial agents
drug metabolism
Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase
期刊论文
ACS INFECTIOUS DISEASES, 2020, 卷号: 6, 期号: 11, 页码: 2994-3003
作者:
Butler, Joshua H.
;
Baptista, Rodrigo P.
;
Valenciano, Ana L.
;
Zhou, Bin
;
Kissinger, Jessica C.
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/05/24
Plasmodium
PfPARE
structure-resistance relationship study
Malaria Box
Pathogen Box
lindenane sesquiterpenoid dimers
Discovery of 6 '-chloro-N-methyl-5 '-(phenylsulfonamido)-[3,3 '-bipyridine]-5-carboxamide (CHMFL-PI4K-127) as a novel Plasmodium falciparum PI(4)K inhibitor with potent antimalarial activity against both blood and liver stages of Plasmodium
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 188
作者:
Liang, Xiaofei
;
Jiang, Zongru
;
Huang, Zhenghui
;
Li, Feng
;
Chen, Cheng
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/11/26
PI4K kinase
Kinase inhibitor
Malaria
Blood stage
Liver stage
Targeting virulence factors as an antimicrobial approach: Pigment inhibitors
期刊论文
MEDICINAL RESEARCH REVIEWS, 2020, 卷号: 40, 期号: 1, 页码: 293-338
作者:
Ni, Shuaishuai
;
Li, Baoli
;
Xu, Yixiang
;
Mao, Fei
;
Li, Xiaokang
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2020/07/01
antimicrobial
colored pathogens
CrtN inhibitor
staphyloxanthin
virulence factor pigment
Characterisation of naturally occurring isothiocyanates as glutathione reductase inhibitors
期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2020, 卷号: 35
作者:
Li, Xia
;
Ni, Maowei
;
Xu, Xiaoling
;
Chen, Wei
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/11/30
Glutathione reductase
isothiocyanate
inhibitor
thiocarbamoylation
Quantitative Analysis of Artemisinin Derivatives: Applications and Techniques
期刊论文
SEPARATION AND PURIFICATION REVIEWS, 2019, 卷号: 48, 期号: 3, 页码: 242-266
作者:
Zhang, Lili
;
Jiang, Yanyan
;
Li, Ning
;
Pu, Yiqiong
;
Zhang, Tong
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
Artemisinin derivatives
quantitative analysis
spectroscopy
chromatography
mass spectrometry
©版权所有 ©2017 CSpace - Powered by
CSpace