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上海药物研究所 [41]
复旦大学上海医学院 [10]
大连化学物理研究所 [4]
厦门大学 [2]
北京大学 [2]
四川大学 [2]
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期刊论文 [64]
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Postoperative Chemoradiotherapy With Capecitabine and Oxaliplatin vs Capecitabine for Stage II to III Rectal Cancer A Randomized Clinical Trial
期刊论文
JAMA NETWORK OPEN, 2021, 卷号: 4
作者:
Li, Ning
;
Zhu, Yuan
;
Liu, Lu-Ying
;
Feng, Yan-Ru
;
Wang, Wen-Ling
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/01/10
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
Simultaneous determination of forsythin and its major metabolites in human plasma via liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 7
作者:
Pan, Lu-lu
;
Chen, Tao
;
Hui, Min
;
Wang, Shuo
;
Fu, Li
收藏
  |  
浏览/下载:134/0
  |  
提交时间:2021/05/24
LC-MS/MS
Forsythin
Aglycone glucuronide
Aglycone sulfate
Pharmacokinetics
Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
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  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
vicagrel
[C-14]vicagrel
vicagrel pharmacokinetics
vicagrel metabolism
mass balance
P2Y(12) receptor inhibitor
A phase II randomized trial of sodium oligomannate in Alzheimer's dementia
期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2020, 卷号: 12, 期号: 1, 页码: 10
作者:
Wang, Tao
;
Kuang, Weihong
;
Chen, Wei
;
Xu, Wenwei
;
Zhang, Liming
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2020/12/21
Sodium oligomannate
Efficacy
Safety
Alzheimer's disease
Clinical trial
Cancer nanomedicine meets immunotherapy: opportunities and challenges
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 7, 页码: 954-958
作者:
Sun, Qingxue
;
Bai, Xiangyang
;
Sofias, Alexandros Marios
;
van der Meel, Roy
;
Ruiz-Hernandez, Eduardo
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/12/24
nanomedicine
immunotherapy
targeting
combination therapy
clinical translation
Qualitative and quantitative determination of anaprazole and its major metabolites in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 183, 页码: 10
作者:
Tang, Chongzhuang
;
Li, Liang
;
Ma, Xifeng
;
Wang, Jin
;
Chen, Bo
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/07/01
Metabolite identification
LC-MS/MS
UPLC-UV/Q-TOF
Anaprazole
Discovery of a novel protein kinase C activator from Croton tiglium for inhibition of non-small cell lung cancer
期刊论文
PHYTOMEDICINE, 2019, 卷号: 65, 页码: 11
作者:
Wang Yuwei
;
Tang Chunping
;
Yao Sheng
;
Lai Huanling
;
Li Runze
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
Natural product
Croton tiglium
Protein kinase C
Molecular modelling
Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6
作者:
Liu, Xiaoyun
;
Li, Wei
;
Zhang, Yifan
;
Jian, Yong
;
Zhao, Qianyu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
LC-MS/MS
Alflutinib
AST2818
Pharmacokinetics
Human plasma
Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310
作者:
Pan, Lulu
;
Guo, Shuang
;
Chen, Xiaoyan
;
Jiang, Xiangrui
;
Shen, Jingshan
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/07/01
TPNI71
Metabolism
UPLC/Q-TOF MS
High-resolution mass spectrometry
Metabolite identification
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