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Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-A beta Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 14, 页码: 21
作者:  Jiang, Cheng-Shi;  Ge, Yong-Xi;  Cheng, Zhi-Qiang;  Wang, Yin-Yin;  Tao, Hong-Rui
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/01
Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors 期刊论文
Bioorganic chemistry, 2018, 卷号: 83, 页码: 277-288
作者:  Cheng, Zhi-Qiang;  Zhu, Kong-Kai;  Zhang, Juan;  Song, Jia-Li;  Muehlmann, Luis Alexandre
收藏  |  浏览/下载:51/0  |  提交时间:2019/01/08
Competitive Inhibition Mechanism of Acetylcholinesterase without Catalytic Active Site Interaction: Study on Functionalized C-60 Nanoparticles via in Vitro and in Silico Assays 期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2017, 卷号: 9, 期号: 22, 页码: 18626-18638
作者:  Liu, Yanyan;  Yan, Bing;  Winkler, David A.;  Fu, Jianjie;  Zhang, Aigian
收藏  |  浏览/下载:20/0  |  提交时间:2018/07/26
Competitive Inhibition Mechanism of Acetylcholinesterase without Catalytic Active Site Interaction: Study on Functionalized C-60 Nanoparticles via in Vitro and in Silico Assays 期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2017, 卷号: 9, 期号: 22, 页码: 18626-18638
作者:  Liu, Yanyan;  Yan, Bing;  Winkler, David A.;  Fu, Jianjie;  Zhang, Aigian
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/12
The impact of crystallization conditions on structure-based drug design: A case study on the methylene blue/acetylcholinesterase complex 期刊论文
PROTEIN SCIENCE, 2016, 卷号: 25, 期号: 6, 页码: 1096-1114
作者:  Dym, Orly;  Song, Wanling;  Felder, Clifford;  Roth, Esther;  Shnyrov, Valery
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Microbial community changes along the active seepage site of one cold seep in the Red Sea 期刊论文
FRONTIERS IN MICROBIOLOGY, 2015, 卷号: 6, 期号: 1
作者:  Wang, Yong;  Cao, Huiluo;  Zhang, Weipeng;  Qian, Pei-Yuan
收藏  |  浏览/下载:20/0  |  提交时间:2015/12/01
Syntheses of coumarin-tacrine hybrids as dual-site acetylcholinesterase inhibitors and their activity against butylcholinesterase, A beta aggregation, and beta-secretase 期刊论文
Bioorganic and Medicinal Chemistry, 2014, 卷号: 22, 期号: 17, 页码: 4784-4791
作者:  Sun, Qi;  Peng, Da-Yong;  Yang, Sheng-Gang;  Zhu, Xiao-Lei;  Yang, Wen-Chao*
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/23
化合物DB-02和SJP-L-5体外抗HIV-1活性及耐药性机制研究 学位论文
博士, 北京: 中国科学院研究生院, 2013
作者:  张兴杰
收藏  |  浏览/下载:24/0  |  提交时间:2014/02/11
Discovery of novel 2,6-disubstituted pyridazinone derivatives as acetylcholinesterase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 63, 页码: 95-103
作者:  Xing, Weiqiang;  Fu, Yan;  Shi, Zhangxing;  Lu, Dong;  Zhang, Haiyan
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
Supramolecular Self-Assembly of 1D and 3D Heterometallic Coordination Polymers with Triruthenium Building Blocks 期刊论文
chemistry a european journal, 2012
Chan, Sharon Lai-Fung; Gao, Song; Chui, Stephen Sin-Yin; Shek, Lam; Huang, Jie-Sheng; Che, Chi-Ming
收藏  |  浏览/下载:4/0  |  提交时间:2015/11/12


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