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Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 7, 页码: 1885-1902
作者:  Wu, Xu;  Yin, Chun;  Ma, Jiang;  Chai, Stella;  Zhang, Chunyuan
收藏  |  浏览/下载:39/0  |  提交时间:2021/11/04
Discovery and anti-inflammatory evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3 beta (GSK-3 beta) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 20
作者:  Gao, Yang;  Zhang, Peng;  Cui, Anfeng;  Ye, De-Yong;  Xiang, Meng
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/05
LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 8, 页码: 1104-1119
作者:  Guo, Xiao-dan;  Sun, Guang-long;  Zhou, Ting-ting;  Wang, Yi-yang;  Xu, Xin
收藏  |  浏览/下载:41/0  |  提交时间:2019/01/08
The discovery of novel benzothiazinones as highly selective non-ATP competitive glycogen synthase kinase 3 beta inhibitors for the treatment of ovarian cancer 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 135
作者:  Gao, Yang;  Ye, De-Yong;  Zhou, Wei-Cheng;  Chu, Yong
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/05
Structure of a Pancreatic ATP-Sensitive Potassium Channel 期刊论文
CELL, 2017
Li, Ningning; Wu, Jing-Xiang; Ding, Dian; Cheng, Jiaxuan; Gao, Ning; Chen, Lei
收藏  |  浏览/下载:5/0  |  提交时间:2017/12/03
Small molecule lx2343 ameliorates cognitive deficits in ad model mice by targeting both amyloid beta production and clearance 期刊论文
Acta pharmacologica sinica, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:  Guo, Xiao-dan;  Sun, Guang-long;  Zhou, Ting-ting;  Xu, Xin;  Zhu, Zhi-yuan
收藏  |  浏览/下载:39/0  |  提交时间:2019/05/09
Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid beta production and clearance 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:  Guo, Xiao-dan;  Sun, Guang-long;  Zhou, Ting-ting;  Xu, Xin;  Zhu, Zhi-yuan
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizing ATP-binding cassette subfamily B member 1 transporter function 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 8, 页码: 9389-9404
作者:  Chen, Gang;  Liu, Junhua;  Chen, Wantao;  Xu, Qin;  Xiao, Meng
收藏  |  浏览/下载:30/0  |  提交时间:2019/01/08
Discovery of Non-ATP-Competitive Inhibitors of Polo-like Kinase1 期刊论文
CHEMMEDCHEM, 2016
Yun, Taikangxiang; Qin, Tan; Liu, Ying; Lai, Luhua
收藏  |  浏览/下载:3/0  |  提交时间:2017/12/03
Discovery of Non-ATP-Competitive Plk1 Inhibitors 其他
2016-01-01
Taikangxiang Yun; Tan Qin; Ying Liu; Luhua Lai
收藏  |  浏览/下载:2/0  |  提交时间:2017/12/03


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