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E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2
期刊论文
EMBO REPORTS, 2022
作者:
Li, Hui
;
Wang, Ning
;
Jiang, Yu
;
Wang, Haofei
;
Xin, Zengfeng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/22
IL-17R signaling
inflammation
MEKK2
NEDD4L
ubiquitination
Inhibition of MAPK/ERK pathway promotes oligodendrocytes generation and recovery of demyelinating diseases
期刊论文
GLIA, 2019, 卷号: 67, 期号: 7, 页码: 1320-1332
作者:
Suo, Na
;
Guo, Yu-e
;
He, Bingqing
;
Gu, Haifeng
;
Xie, Xin
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
differentiation
ERK
MAPK
MEK inhibitor
myelin
oligodendrocyte
oligodendrocyte progenitor cell
remyelination
Silica nanoparticle exposure during the neonatal period impairs hippocampal precursor proliferation and social behavior later in life
期刊论文
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2018, 卷号: 13, 页码: 3593-3608
作者:
Gu ZJ(谷战军)
;
Gao, JW
;
Fu, JJ
;
Fan, XT
;
Zhu, JC
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/09/24
silica nanoparticles
nanotoxicity
hippocampal neurogenesis
neuroinfla mation
social behavior
Upregulation of Neural Precursor Cell Expressed Developmentally Downregulated 4-1 is Associated with Poor Prognosis and Chemoresistance in Lung Adenocarcinoma
期刊论文
中华医学杂志(英文版), 2018, 卷号: 131, 期号: 1, 页码: 16-24
作者:
Song, Ying-Hua
;
Zhang, Cai-Qing
;
Chen, Fang-Fang
;
Lin, Xiao-Yan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Chemoresistance
Lung Adenocarcinoma
NEDD4?1
PTEN 10
Prognosis
Upregulation of Neural Precursor Cell Expressed Developmentally Downregulated 4-1 is Associated with Poor Prognosis and Chemoresistance in Lung Adenocarcinoma
期刊论文
中华医学杂志:英文版, 2018, 期号: 01
作者:
Ying-Hua Song[1]
;
Cai-Qing Zhang[1]
;
Fang-Fang Chen[1]
;
Xiao-Yan Lin[2]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
Myelin injury in the central nervous system and Alzheimer's disease
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 162-168
作者:
Wang, Sha-Sha
;
Zhang, Zhao
;
Zhu, Tian-Bi
;
Chu, Shi-Feng
;
He, Wen-Bin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/27
OLG
oligodendrocyte
CNS
central nervous system
SC
Schwann cell
PNS
peripheral nervous system
MBP
myelin basic protein
PLP
proteolipid protein
P0/MPZ
myelin protein zero
EAE
experimental allergic encephalomyelitis
MS
multiple sclerosis
CNP
2′ 3′-cyclic nucleotide 3′-phosphodiesterase
MAG
myelin associated glycoprotein
MOG
myelin oligodendrocyte glycoprotein
AD
Alzheimer's disease
OPC
oligodendrocyte precursor cell
NPC
neural progenitor cell
ROS
reactive oxygen species
TNF
tumour necrosis factor
AIF
apoptosis-inducing factor
IFN-γ
interferon gamma
ERK1/2
extracellular signal-regulated kinases-1 and -2
MAPK
mediators of mitogen-activated protein kinase
FGFR1/2
fibroblast growth factor receptors-1 and -2
Dock3
dedicator of cytokinesis 3
PERK
pancreatic endoplasmic reticulum kinase
GEF
guanine nucleotide exchange factor
SIRT2
sirtuin 2
NOD2
Nucleotide-binding oligomerization domain containing protein 2
RIPK2
receptor-interacting serine/threonine kinase 2
Shh
Sonic Hedgehog
NMO
neuromyelitis optica
ADEM
acute disseminated encephalomyelitis
ANHLE
acute necrotizing hemorrhagic leukoencephalitis
CPM
central pontine myelinolysis
Aβ
beta-amyloid
SP
senile plaque
NFT
neurofibrillary tangle
MRI
magnetic resonance imaging
Myelin
Oligodendrocyte
Demyelination
Neurodegenerative diseases
Alzheimer’s disease
Chemokines play complex roles in cerebral ischemia
期刊论文
Neurochemistry International, 2018, 卷号: 112, 页码: 146-158
作者:
Chen, Chen
;
Chu, Shi-Feng
;
Liu, Dan-Dan
;
Zhang, Zhao
;
Kong, Ling-Lei
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/12/27
Chemokine
Cerebral ischemia
Ischemic stroke
IS
ischemic stroke
NSCs
neural stem cell
NPCs
neural progenitor cells
BMSCs
bone marrow stromal cells
ELR
glutamic acid-leucine-arginine
MCP
monocytes chemoattractant protein
MCAo
middle cerebral artery occlusion
tMCAo
transient MCAo
CNS
central nervous system
MIP
macrophage inflammatory protein
BBB
blood brain barrier
HI
hypoxia ischemia
CSF
cerebrospinal fluid
CI
cerebral infarction
WT
wildtype
pMCAo
permanent MCAo
ET
endothelin
I/R
ischemia/reperfusion
SCID
Severe Combined Immunodeficiency
ENA-78
epithelial neutrophil-activating peptide-78
IL-8
interleukin 8
PMNL
polymorphonuclear leukocyte
MSCs
mesenchymal stem cells
VEGF
vascular endothelial growth factor
CINC
cytokine-induced neutrophil chemoattractant
IP-10
interferon-gamma inducible protein-10
NK
natural killer
SDF-1
stromal cell-derived factor-1
EPCs
endothelial progenitor cells
HSCs
hematopoietic stem cells
HUVECs
human umbilical vein endothelial cells
TIA
transient ischemic attack
OGD
oxygen glucose deprivation
GPCs
glial precursor cells
CMKLR1
chemerin-like receptor-1
AIS
acute ischemic stroke
CKLF1
chemokine-like factor 1
CBP
chemokine-binding protein
Neural precursor cell expressed, developmentally downregulated 8-activating enzyme inhibitor MLN4924 sensitizes colorectal cancer cells to oxaliplatin by inducing DNA damage, G2 cell cycle arrest and apoptosis
期刊论文
MOLECULAR MEDICINE REPORTS, 2017, 卷号: 15, 期号: 5
作者:
Zheng, Wanwei
;
Luo, Zhongguang
;
Zhang, Jun
;
Min, Pei
;
Li, Wenshuai
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
MLN4924
oxaliplatin
DNA damage response
G2 cell cycle arrest
apoptosis
colorectal cancer
A Rhodium(III) Complex as an Inhibitor of Neural Precursor Cell Expressed, Developmentally Down-Regulated 8-Activating Enzyme with in Vivo Activity against Inflammatory Bowel Disease
期刊论文
2017, 卷号: 60, 期号: [db:dc_citation_issue], 页码: 497
作者:
Zhong, Hai-Jing[1]
;
Wang, Wanhe[2]
;
Kang, Tian-Shu[1]
;
Yan, Hui[3,4]
;
Yang, Yali[3,4]
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
Overexpression of NEDD9 in renal cell carcinoma is associated with tumor migration and invasion
期刊论文
ONCOLOGY LETTERS, 2017, 卷号: 14, 期号: 6, 页码: 8021-8027
作者:
Wang, Jue
;
Wang, Si
;
Luan, Yun
;
Zhang, Wenhua
;
Sun, Chao
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/11
neural precursor cell expressed developmentally downregulated 9
renal
cell carcinoma
clinicopathological factors
migration
invasion
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