×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [26]
上海生物化学与细胞生... [3]
北京大学 [2]
兰州大学 [2]
大连化学物理研究所 [1]
中国科学院大学 [1]
更多...
内容类型
期刊论文 [36]
专利 [1]
发表日期
2023 [1]
2021 [1]
2019 [1]
2018 [2]
2017 [1]
2015 [1]
更多...
学科主题
Biochemist... [2]
Neuroscien... [2]
Pharmacolo... [2]
Biochemist... [1]
Chemistry [1]
behavioral... [1]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共37条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Rxrs and their partner receptor genes inducing masculinization plausibly mediated by endocrine disruption in Paralichthys olivaceus
期刊论文
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2023, 卷号: 226, 页码: 14
作者:
Zou, Congcong
;
Wang, Lijuan
;
Shu, Chang
;
Tan, Xungang
;
Wu, Zhihao
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/02/01
Retinoid X receptors
Steroidogenesis
Sex differentiation
LG100268
Gonad
Flounder
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:
He, Qian
;
Wei, Yuanyuan
;
Liu, Xiao
;
Ye, Rongrong
;
Kong, Linghui
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2021/11/04
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:
Xiao, Li
;
Wang, Yujun
;
Zhang, Mumei
;
Wu, Weiwei
;
Kong, Linghui
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2020/07/01
Pharmacological Characterization of Dezocine, a Potent Analgesic Acting as a kappa Partial Agonist and mu Partial Agonist
期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:
Wang, Yu-Hua
;
Chai, Jing-Rui
;
Xu, Xue-Jun
;
Ye, Ru-Feng
;
Zan, Gui-Ying
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2019/01/08
Clinical opioids differentially induce co-internalization of mu- and delta-opioid receptors
期刊论文
MOLECULAR PAIN, 2018, 卷号: 14, 期号: 1, 页码: 1-15
作者:
Bao, Fenghua
;
Li, Chang-Lin
;
Lu, Ying-Jin
;
Zhang, Xu
;
Chen, Xu-Qiao
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/04/28
Protein-coupled Receptors
Knock-out Mice
Morphine Antinociceptive Tolerance
Dorsal-root Ganglia
Opiate Tolerance
Beta-arrestin
Desensitization
Trafficking
Dependence
Analgesia
The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent kappa-Opioid Agonistic Activities
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 4, 页码: 766-776
作者:
Li, Wei
;
Long, Jian-Dong
;
Qian, Yuan-Yuan
;
Long, Yu
;
Xu, Xue-Jun
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
kappa-opioid receptor
mu-opioid receptor
nepenthones
4,5-epoxymorphinans
pharmacological heterogeneity
structure activity relationship
binding structure
Novel kappa-opioid receptor agonist MB-1C-OH produces potent analgesia with less depression and sedation
期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 5, 页码: 565-571
作者:
Zhang, Le-sha
;
Wang, Jun
;
Chen, Jian-chun
;
Tao, Yi-min
;
Wang, Yu-hua
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
kappa-opioid receptor
MB-1C-OH
(-)U50,488H
Nor-BNI
morphine
pain
acetic acid-induced writhing
formalin test
depression
sedation
Structural Feature Studies on Spiropiperidine Analogues as Agonists of Delta Opioid Receptors
期刊论文
progress in biochemistry and biophysics, 2013, 卷号: 40, 期号: 7, 页码: 668-677
作者:
Gao Wei-Min
;
Li Yan
;
Zhang Shu-Wei
;
Yang Ling
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2015/11/09
N-substituted spiropiperidine analogues
DOR agonist
3D-QSAR
CoMFA
CoMSIA
beta-Adrenergic-stimulated L-type channel Ca2+ entry mediates hypoxic Ca2+ overload in intact heart
期刊论文
journal of molecular and cellular cardiology, 2013
Zhang, Huiliang
;
Shang, Wei
;
Zhang, Xing
;
Gu, Jingli
;
Wang, Xianhua
;
Zheng, Ming
;
Wang, Yanru
;
Zhou, Zhuan
;
Cao, Ji-Min
;
Ji, Guangju
;
Zhang, Rongli
;
Cheng, Heping
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/11
Hypoxia
L-type Ca2+ channel
Mitochondria
beta-Adrenergic stimulation
Ex vivo heart imaging
ACCELERATED PHOSPHOLIPID DEGRADATION
MYOCARDIAL INTERSTITIAL NOREPINEPHRINE
PERSISTENT SODIUM CURRENT
CARDIAC MYOCYTES
VENTRICULAR MYOCYTES
MEMBRANE DYSFUNCTION
CALCIUM-CHANNEL
CELL INJURY
RAT-HEART
IN-VIVO
Serine 363 of the delta-opioid receptor is crucial for adopting distinct pathways to activate ERK1/2 in response to stimulation with different ligands
期刊论文
JOURNAL OF CELL SCIENCE, 2010, 卷号: 123, 期号: 24, 页码: 4259-4270
作者:
Xu, Chi
;
Hong, Min-Hua
;
Zhang, Le-Sha
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
beta-arrestins
GPCR
GRK
ERK
delta-opioid receptor
Serine 363 phosphorylation
©版权所有 ©2017 CSpace - Powered by
CSpace