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A multifunctional bis--nor-meptazinol-oxalamide hybrid with metal-chelating property ameliorates Cu-induced spatial learning and memory deficits via preventing neuroinflammation and oxido-nitrosative stress in mice 期刊论文
Journal of Trace Elements in Medicine and Biology, 2019, 卷号: Vol.52, 页码: 199-208
作者:  Xiaofang Tan;  Yan Zhou;  Ping Gong;  Huifeng Guan;  Baichuan Wu
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/13
A multifunctional bis--nor-meptazinol-oxalamide hybrid with metal-chelating property ameliorates Cu-induced spatial learning and memory deficits via preventing neuroinflammation and oxido-nitrosative stress in mice. 期刊论文
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2019, 卷号: Vol.52, 页码: 199-208
作者:  Xiaofang Tan;  Yan Zhou;  Ping Gong;  Huifeng Guan;  Baichuan Wu
收藏  |  浏览/下载:17/0  |  提交时间:2019/12/17
Bis(9)-(-)-Meptazinol, a novel dual-binding AChE inhibitor, rescues cognitive deficits and pathological changes in APP/PS1 transgenic mice 期刊论文
TRANSLATIONAL NEURODEGENERATION, 2018, 卷号: 7
作者:  Shi, Yuhuan;  Huang, Wanying;  Wang, Yu;  Zhang, Rui;  Hou, Lina
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05
新型乙酰胆碱酯酶抑制剂Bis(9)-(-)-Meptazinol的小鼠和大鼠药代动力学研究 期刊论文
现代生物医学进展, 2017, 期号: 6
作者:  史玉欢;  赵恒毅;  葛新星;  郑兆浠;  王宇
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/05
Pharmacophore-based design and discovery of (-)-meptazinol carbamates as dual modulators of cholinesterase and amyloidogenesis 期刊论文
Journal of Enzyme Inhibition and Medicinal Chemistry, 2017, 卷号: 32, 期号: 1
作者:  Xie, Qiong;  Zheng, Zhaoxi;  Shao, Biyun;  Fu, Wei;  Xia, Zheng
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/05
(-)-Meptazinol-melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-beta aggregation with high antioxidant potency for Alzheimer's therapy 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 13
作者:  Cheng, Shaobing;  Zheng, Wei;  Gong, Ping;  Zhou, Qiang;  Xie, Qiong
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/05
(-)-Meptazinol-melatonin hybrids as novel dual inhibitors of cholinesterases and amyloid-beta aggregation with high antioxidant potency for Alzheimer's therapy 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 13
作者:  Cheng, Shaobing;  Zheng, Wei;  Gong, Ping;  Zhou, Qiang;  Xie, Qiong
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/19
Theoretical and NMR investigations on the conformations of (-)-meptazinol hydrochloride in solution 期刊论文
MOLECULAR SIMULATION, 2013, 卷号: 39, 期号: 13
作者:  Li, Wei;  Xu, Li-li;  Xie, Qiong;  Chen, Yan;  Lu, Mei-yan
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/19
Bis(9)-(-)-nor-meptazinol as a novel dual-binding AChEI potently ameliorates scopolamine-induced cognitive deficits in mice 期刊论文
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2013, 卷号: 104
作者:  Liu, Ting;  Xia, Zheng;  Zhang, Wei-Wei;  Xu, Jian-rong;  Ge, Xin-Xing
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/19
Novel bis-(-)-nor-meptazinol derivatives act as dual binding site AChE inhibitors with metal-complexing property 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 264, 期号: 1
作者:  Zheng, Wei;  Li, Juan;  Qiu, Zhuibai;  Xia, Zheng;  Li, Wei
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/19


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