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Biological roles of LSD1 beyond its demethylase activity
期刊论文
CELLULAR AND MOLECULAR LIFE SCIENCES, 2020
作者:
Gu, Feiying
;
Lin, Yuxin
;
Wang, Zhun
;
Wu, Xiaoxin
;
Ye, Zhenyue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/11/26
LSD1
Demethylase
Ubiquitylation
FBXW7
Non-catalytic
Inhibition of Ezh2 In Vitro and the Decline of Ezh2 in Developing Midbrain Promote Dopaminergic Neurons Differentiation Through Modifying H3K27me3
期刊论文
STEM CELLS AND DEVELOPMENT, 2019, 卷号: 28, 期号: 10, 页码: 649-658
作者:
Hong, Feng
;
Zhao, Mengxue
;
Zhang, Lei
;
Feng, Linyin
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
dopaminergic neurons
Ezh2
Nurr1
neural stem cells
Distal-less homeobox 5 promotes the osteo-/dentinogenic differentiation potential of stem cells from apical papilla by activating histone demethylase KDM4B through a positive feedback mechanism
期刊论文
Experimental Cell Research, 2019, 卷号: Vol.374 No.1, 页码: 221-230
作者:
Haoqing Yang
;
Jiao Fan
;
Yangyang Cao
;
Runtao Gao
;
Zhipeng Fan
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/13
Osteo-/dentinogenic
differentiation
Lysine-specific
demethylase
4B
(KDM4B)
Distal-less
homeobox
5
(DLX5)
Stem
cells
from
apical
papilla
(SCAPs)
Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts
期刊论文
BONE RESEARCH, 2018, 卷号: 6, 期号: 14, 页码: -
作者:
Sun, Jun
;
Niu, Ningning
;
Yan, Guang
;
Yang, Yang
;
Zou, Weiguo
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/04/28
Mesenchymal Stem-cells
Brachydactyly Type A2
Gene-expression
Differentiation
Activation
Mouse
Methylation
Repression
Mutations
Leukemia
Distal-less homeobox 5 promotes the osteo-/dentinogenic differentiation potential of stem cells from apical papilla by activating histone demethylase KDM4B through a positive feedback mechanism
期刊论文
Experimental Cell Research, 2018
作者:
Haoqing Yang
;
Jiao Fan
;
Yangyang Cao
;
Runtao Gao
;
Zhipeng Fan
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/26
Osteo-/dentinogenic
differentiation
Lysine-specific
demethylase
4B
(KDM4B)
Distal-less
homeobox
5
(DLX5)
Stem
cells
from
apical
papilla
(SCAPs)
Novel spirocyclic tranylcypromine derivatives as lysine-specific demethylase 1 (LSD1) inhibitors
期刊论文
RSC ADVANCES, 2018, 卷号: 8, 期号: 3, 页码: 1666-1676
作者:
Shi, Ying
;
Wu, Yan-Ran
;
Su, Ming-Bo
;
Shen, Dong-Hao
;
Gunosewoyo, Hendra
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 141, 页码: 101-112
作者:
Ji, Yue-Yang
;
Lin, Sen-Dong
;
Wang, Yu-Jie
;
Su, Ming-Bo
;
Zhang, Wei
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Tranylcypromine
LSD1
Stereoselective cyclopropanation
Chiral synthesis
MAO-A
MAO-B
ATM-mediated KDM2A phosphorylation is required for the DNA damage repair
期刊论文
ONCOGENE, 2016
Cao, L-L
;
Wei, F.
;
Du, Y.
;
Song, B.
;
Wang, D.
;
Shen, C.
;
Lu, X.
;
Cao, Z.
;
Yang, Q.
;
Gao, Y.
;
Wang, L.
;
Zhao, Y.
;
Wang, H.
;
Yang, Y.
;
Zhu, W-G
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
DOUBLE-STRAND BREAKS
HISTONE H3
MRE11-RAD50-NBS1 COMPLEX
HOMOLOGOUS RECOMBINATION
CELLULAR-RESPONSE
GENOTOXIC STRESS
MRE11 COMPLEX
SITES
DEMETHYLASE
METHYLATION
REF6 recognizes a specific DNA sequence to demethylate H3K27me3 and regulate organ boundary formation in Arabidopsis
期刊论文
NATURE GENETICS, 2016, 卷号: 48, 期号: 6, 页码: 694-+
作者:
Cui, Xia
;
Lu, Falong
;
Qiu, Qi
;
Zhou, Bing
;
Gu, Lianfeng
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2017/04/17
Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:
Sun, Hao
;
Zheng, Hui
;
Guo, Yunqian
;
Pei, Duanqing
;
He, Songwei
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2018/12/13
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