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Divalent tranylcypromine derivative as lysine-specific demethylase 1 inhibitor
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2021, 页码: 8
作者:
Sun, Yin
;
Li, Na
;
Su, Mingbo
;
Wang, Xiaowen
;
Zhao, Dongmei
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/05/24
Divalent tranylcypromine
LSD1 inhibitor
MV4-11 antiproliferative activity
CD86 mRNA expression
Linker
Selectivity
Biological roles of LSD1 beyond its demethylase activity
期刊论文
CELLULAR AND MOLECULAR LIFE SCIENCES, 2020
作者:
Gu, Feiying
;
Lin, Yuxin
;
Wang, Zhun
;
Wu, Xiaoxin
;
Ye, Zhenyue
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/11/26
LSD1
Demethylase
Ubiquitylation
FBXW7
Non-catalytic
Inhibition of Ezh2 In Vitro and the Decline of Ezh2 in Developing Midbrain Promote Dopaminergic Neurons Differentiation Through Modifying H3K27me3
期刊论文
STEM CELLS AND DEVELOPMENT, 2019, 卷号: 28, 期号: 10, 页码: 649-658
作者:
Hong, Feng
;
Zhao, Mengxue
;
Zhang, Lei
;
Feng, Linyin
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
dopaminergic neurons
Ezh2
Nurr1
neural stem cells
The Lysine-Specific Demethylase KDM4A/JMJD2A Acts As a Tumor Suppressor in Multiple Myeloma
期刊论文
BLOOD, 2018, 卷号: 132
作者:
Jin, Fengyan
;
Kumar, Shaji K.
;
Dai, Yun
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  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts
期刊论文
BONE RESEARCH, 2018, 卷号: 6, 期号: 14, 页码: -
作者:
Sun, Jun
;
Niu, Ningning
;
Yan, Guang
;
Yang, Yang
;
Zou, Weiguo
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/04/28
Mesenchymal Stem-cells
Brachydactyly Type A2
Gene-expression
Differentiation
Activation
Mouse
Methylation
Repression
Mutations
Leukemia
Lysine-specific demethylase 2 contributes to the proliferation of small cell lung cancer by regulating the expression of TFPI-2
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 18, 期号: 1, 页码: 733-740
作者:
Cao, Yunfeng
;
Guo, Chunhui
;
Yin, Yanhai
;
Li, Xin
;
Zhou, Ling
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
lysine-specific demethylase 2
tissue factor pathway inhibitor-2
small
cell lung cancer
methylation
Inhibition of lysine-specific demethylase 1 prevents proliferation and mediates cisplatin sensitivity in ovarian cancer cells
期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 15, 期号: 6, 页码: 9025-9032
作者:
Shao, Genbao[1]
;
Wan, Xiaolei[2]
;
Lai, Wensheng[3]
;
Wu, Chaoyang[4]
;
Jin, Jie[5]
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/24
lysine-specific demethylase 1
proliferation
apoptosis
cisplatin
ovarian cancer
KDM3A inhibition attenuates high concentration insulin-induced vascular smooth muscle cell injury by suppressing MAPK/NF-kappa B pathways
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2018, 卷号: 41, 期号: 3
作者:
Zhang, Bo-Fang
;
Jiang, Hong
;
Chen, Jing
;
Guo, Xin
;
Hu, Qi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
lysine (K)-specific demethylase 3A
vascular smooth muscle cells
insulin
mitogen-activated protein kinase/nuclear factor-kappa B
Novel spirocyclic tranylcypromine derivatives as lysine-specific demethylase 1 (LSD1) inhibitors
期刊论文
RSC ADVANCES, 2018, 卷号: 8, 期号: 3, 页码: 1666-1676
作者:
Shi, Ying
;
Wu, Yan-Ran
;
Su, Ming-Bo
;
Shen, Dong-Hao
;
Gunosewoyo, Hendra
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 141, 页码: 101-112
作者:
Ji, Yue-Yang
;
Lin, Sen-Dong
;
Wang, Yu-Jie
;
Su, Ming-Bo
;
Zhang, Wei
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Tranylcypromine
LSD1
Stereoselective cyclopropanation
Chiral synthesis
MAO-A
MAO-B
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