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Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235
作者:  Qu, Bingxue;  Xu, Yongjin;  Lu, Yang;  Zhuang, Weihao;  Jin, Xinxin
收藏  |  浏览/下载:15/0  |  提交时间:2022/12/23
Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9217-9237
作者:  Liang, Xuewu;  Sun, Chenxia;  Li, Chunpu;  Yu, Haolan;  Wei, Xiaohui
收藏  |  浏览/下载:23/0  |  提交时间:2021/08/17
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:  Zhou, Yu;  Li, Xiaoguang;  Chen, Kerong;  Ba, Qian;  Zhang, Xu
收藏  |  浏览/下载:40/0  |  提交时间:2021/06/11
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:  Zhou, Yu;  Li, Xiaoguang;  Chen, Kerong;  Ba, Qian;  Zhang, Xu
收藏  |  浏览/下载:41/0  |  提交时间:2021/05/24
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei;  Wang, Juan;  Ding, Huaqian
收藏  |  浏览/下载:31/0  |  提交时间:2021/05/24
Design, synthesis and biological evaluation of novel thiohydantoin derivatives as potent androgen receptor antagonists for the treatment of prostate cancer 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 31, 页码: 13
作者:  Wang, Ao;  Wang, Yawan;  Meng, Xin;  Yang, Yushe
收藏  |  浏览/下载:16/0  |  提交时间:2021/05/24
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan
收藏  |  浏览/下载:21/0  |  提交时间:2021/05/24
Automated design and optimization of multitarget schizophrenia drug candidates by deep learning 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16
作者:  Tan, Xiaoqin;  Jiang, Xiangrui;  He, Yang;  Zhong, Feisheng;  Li, Xutong
收藏  |  浏览/下载:38/0  |  提交时间:2020/12/21
Rational Design and Evaluation of 6-(Pyrimidin-2-ylamino)-3,4-dihydroquinoxalin-2(1H)-ones as Polypharmacological Inhibitors of BET and Kinases 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 17, 页码: 9787-9802
作者:  Lv, Kaikai;  Chen, Weicong;  Chen, Danqi;  Mou, Jie;  Zhang, Huijie
收藏  |  浏览/下载:12/0  |  提交时间:2020/12/21
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan
收藏  |  浏览/下载:24/0  |  提交时间:2020/12/24


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