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Neurochondrin Antibody Serum Positivity in Three Cases of Autoimmune Cerebellar Ataxia 期刊论文
CEREBELLUM, 2019, 卷号: 18, 期号: 6, 页码: 1137-1142
作者:  Zhang Weihua;  Ren Haitao;  Fang Fang;  Yang Xunzhe;  Wang Jing
收藏  |  浏览/下载:63/0  |  提交时间:2020/02/29
Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance 期刊论文
JOURNAL OF CLINICAL INVESTIGATION, 2019, 卷号: 129, 期号: 6
作者:  Pan, Chaoyun;  Jin, Lingtao;  Wang, Xu;  Li, Yuancheng;  Chun, Jaemoo
收藏  |  浏览/下载:26/0  |  提交时间:2019/12/05
DMT efficiently inhibits hepatic gluconeogenesis by regulating the G alpha q signaling pathway 期刊论文
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2017, 卷号: 59, 期号: 2, 页码: 151-169
作者:  Zhou, Ting-Ting;  Ma, Fei;  Shi, Xiao-Fan;  Xu, Xin;  Du, Te
收藏  |  浏览/下载:33/0  |  提交时间:2019/01/08
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells 期刊论文
Cellular Signalling, 2016, 卷号: 28, 期号: 8, 页码: 1099-1104
作者:  Wang, Jing;  Yang, Xin;  Zhang, Jingjing*
收藏  |  浏览/下载:28/0  |  提交时间:2019/12/03
4E-BP1  4E binding protein  AMPK  AMP-activated protein kinase  ATF6  activating transcription factor 6  ATP  adenosine triphosphate  DEPTOR  DEP domain containing mTOR-interacting protein  CI  complexes I  CII  complex II  CIII  complex III  CIV  complex IV  CV  complex V  eIF2α  Eukaryotic Initiation Factor 2α  ER  Endoplasmic Reticulum  ERAD  ER-associated degradation  ERO1α  ER oxidoreductase 1 α  FoxO1  Forkhead box O1  GβL  G Protein β Subunit Like Protein  GRP78  78 kDa glucose-regulated protein precursor  GSIS  glucose-stimulated insulin secretion  IRE1  Inositol-requiring enzyme 1  IRS1  Insulin receptor substrate 1  IRS2  Insulin receptor substrate 2  mLST8  mammalian lethal with sec-13 protein 8  mSin1  the mammalian stress-activated MAP kinase-interaction protein 1  mtDNA  mitochondrial deoxyribonucleic acid  mTOR  mammalian TOR  mTORC1  mTOR complex 1  mTORC2  mTOR complex 2  NADPH oxidase  Nicotinamide adenine dinucleotide phosphate-oxidase  NOS  nitric oxide synthase  O2–·  superoxide anion  H2O2  hydrogen peroxide  OH·  hydroxyl radical  3O2  triplet-state molecular oxygen  OXPHOS  oxidative phosphorylation  CAT  catalase  GPx  glutathioneperoxidase  PERK  Protein kinase R-like endoplasmic reticulum kinase  PDI  ER protein disulfide isomerases  PI3K  the phosphoinositide3-kinase  PRAS40  40-kDa proline-rich Akt substrate  PRAS40  the 40-kDa proline-rich Akt substrate  PROTOR  the protein observed with RICTOR  RAPTOR  regulatory-associated protein of mTOR  RICTOR  The rapamycin-insensitive companion of mTOR  REDD1  DNA damage response 1  RNS  reactive nitrogen species  ROS  reactive oxygen species  RNS  reactive nitrogen species  S6K  S6 kinase  SOD  superoxidedismutase  T1DM  Type 1 diabetes mellitus  T2DM  Type 2 diabetes mellitus  TOR  the target of rapamycin  TSC2  Tuberous sclerosis 2  UPR  unfolded protein response  Mitochondrial oxidative stress  ER stress  mTOR  Pancreatic β cells  
The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect 期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 162, 页码: 179-187
作者:  Chu, Shifeng;  Liu, Shaolin;  Duan, Wenzhen;  Cheng, Yong;  Jiang, Xueying
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/27
Chirality  Clausenamide  Dementia  Long-term potentiation  Signaling pathway  Calcium  6-OHDA  6-hydroxyldopamine  ACE  acetylcholinesterase  ACh  acetylcholine  AD  Alzheimer's disease  AUC0–12 h  0–12 h area under curve  APP  amyloid precursor protein  APV  R-2-amino-5-phosphonopentanoate  AUC0−∝  whole area under curve  BBB  blood–brain barrier  BDNF  brain-derived neurotrophic factor  CaM  calmodulin  CaMKII  calmodulin kinase II  ChAT  choline acetyltransferase  CREB  cAMP responding element binding  CHM  Chinese herbal medicine  clau  clausenamide  CL  clearance  Cmax  maximum concentration  CDK-5  cyclin-dependent kinase-5  DM  diabetes mellitus  DAG  diacylglycerol  ER  endoplasmic reticulum  ERK  extracellular signal-regulated kinases  GSK-3  glycogen synthase kinase-3  IP3  inositol triphosphate  LTP  long term potentiation  MWM  Morris water maze  NGF  nerve growth factor  NMDA  N-Methyl-D-aspartate  D  nNOS  neural nitric oxide synthase  PAT  passive avoidance tasks  Pir  piracetam  PLC  phospholipase C  PP1  phosphate 1  PKC  protein kinase C  tmax  time of peak concentration  t1/2α  absorption half-life  t1/2β  elimination half-life  Tau  microtubule-associated proteins  TCM  traditional Chinese medicine  Vd  apparent volume of distribution  VDCC  voltage-dependent calcium channel  
Astrocytic Ca2+ waves mediate activation of extrasynaptic NMDA receptors in hippocampal neurons to aggravate brain damage during ischemia 期刊论文
疾病神经生物学实验神经学b辑, 2013
Dong, Qi-ping; He, Jing-quan; Chai, Zhen
收藏  |  浏览/下载:2/0  |  提交时间:2015/11/10
Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca2+-dependent cofilin activation and RhoA inhibition 期刊论文
JOURNAL OF CELL SCIENCE, 2011, 卷号: 124, 期号: 2, 页码: 186-197
Huang, Zhi-hui; Wang, Ying; Su, Zhi-da; Geng, Jian-guo; Chen, Yi-zhang; Yuan, Xiao-bing; He, Cheng
收藏  |  浏览/下载:49/0  |  提交时间:2012/07/13
Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca2+-dependent cofilin activation and RhoA inhibition 期刊论文
JOURNAL OF CELL SCIENCE, 2011, 卷号: 124, 期号: 2, 页码: 186-197
作者:  Huang, ZH;  Wang, Y;  Su, ZD;  Geng, JG;  Chen, YZ
收藏  |  浏览/下载:24/0  |  提交时间:2015/07/22
ChIP-seq and Functional Analysis of the SOX2 Gene in Colorectal Cancers 期刊论文
2010
Fang, Xuefeng ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI); Yu, Wei ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI); Li, Lisha ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI); Shao, Jiaofang ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI); Zhao, Na ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI); Chen, Qiyun ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI); Lin, Biaoyang ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI); Zheng, Shu ( Zhejiang Univ, Affiliated Hosp 2, Key Lab Canc Prevent & Intervent, China Nat); Ye, Zhiyun; 叶志云; Lin, Sheng-Cai; 林圣彩
收藏  |  浏览/下载:4/0  |  提交时间:2011/07/12
Src homology 2 domain-containing inositol-5-phosphatase 1 (SITP1) negatively regulates TLR4-mediated LPS response primarily through a phosphatase activity- and PI-3K-independent mechanism 期刊论文
2010, 2010
An, HZ; Xu, HM; Zhang, MH; Zhou, J; Feng, T; Qian, C; Qi, RZ; Cao, XT
收藏  |  浏览/下载:4/0


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