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厦门大学 [4]
上海神经科学研究所 [3]
清华大学 [2]
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期刊论文 [17]
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Neurochondrin Antibody Serum Positivity in Three Cases of Autoimmune Cerebellar Ataxia
期刊论文
CEREBELLUM, 2019, 卷号: 18, 期号: 6, 页码: 1137-1142
作者:
Zhang Weihua
;
Ren Haitao
;
Fang Fang
;
Yang Xunzhe
;
Wang Jing
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2020/02/29
Neurochondrin
NCDN
Autoimmune
Cerebellar
Ataxia
Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance
期刊论文
JOURNAL OF CLINICAL INVESTIGATION, 2019, 卷号: 129, 期号: 6
作者:
Pan, Chaoyun
;
Jin, Lingtao
;
Wang, Xu
;
Li, Yuancheng
;
Chun, Jaemoo
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/05
DMT efficiently inhibits hepatic gluconeogenesis by regulating the G alpha q signaling pathway
期刊论文
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2017, 卷号: 59, 期号: 2, 页码: 151-169
作者:
Zhou, Ting-Ting
;
Ma, Fei
;
Shi, Xiao-Fan
;
Xu, Xin
;
Du, Te
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Gaq signaling
hepatic gluconeogenesis
protein kinase B (AKT)
type 2 diabetes mellitus (T2DM)
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells
期刊论文
Cellular Signalling, 2016, 卷号: 28, 期号: 8, 页码: 1099-1104
作者:
Wang, Jing
;
Yang, Xin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/03
4E-BP1
4E binding protein
AMPK
AMP-activated protein kinase
ATF6
activating transcription factor 6
ATP
adenosine triphosphate
DEPTOR
DEP domain containing mTOR-interacting protein
CI
complexes I
CII
complex II
CIII
complex III
CIV
complex IV
CV
complex V
eIF2α
Eukaryotic Initiation Factor 2α
ER
Endoplasmic Reticulum
ERAD
ER-associated degradation
ERO1α
ER oxidoreductase 1 α
FoxO1
Forkhead box O1
GβL
G Protein β Subunit Like Protein
GRP78
78 kDa glucose-regulated protein precursor
GSIS
glucose-stimulated insulin secretion
IRE1
Inositol-requiring enzyme 1
IRS1
Insulin receptor substrate 1
IRS2
Insulin receptor substrate 2
mLST8
mammalian lethal with sec-13 protein 8
mSin1
the mammalian stress-activated MAP kinase-interaction protein 1
mtDNA
mitochondrial deoxyribonucleic acid
mTOR
mammalian TOR
mTORC1
mTOR complex 1
mTORC2
mTOR complex 2
NADPH oxidase
Nicotinamide adenine dinucleotide phosphate-oxidase
NOS
nitric oxide synthase
O2–·
superoxide anion
H2O2
hydrogen peroxide
OH·
hydroxyl radical
3O2
triplet-state molecular oxygen
OXPHOS
oxidative phosphorylation
CAT
catalase
GPx
glutathioneperoxidase
PERK
Protein kinase R-like endoplasmic reticulum kinase
PDI
ER protein disulfide isomerases
PI3K
the phosphoinositide3-kinase
PRAS40
40-kDa proline-rich Akt substrate
PRAS40
the 40-kDa proline-rich Akt substrate
PROTOR
the protein observed with RICTOR
RAPTOR
regulatory-associated protein of mTOR
RICTOR
The rapamycin-insensitive companion of mTOR
REDD1
DNA damage response 1
RNS
reactive nitrogen species
ROS
reactive oxygen species
RNS
reactive nitrogen species
S6K
S6 kinase
SOD
superoxidedismutase
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TOR
the target of rapamycin
TSC2
Tuberous sclerosis 2
UPR
unfolded protein response
Mitochondrial oxidative stress
ER stress
mTOR
Pancreatic β cells
The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect
期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 162, 页码: 179-187
作者:
Chu, Shifeng
;
Liu, Shaolin
;
Duan, Wenzhen
;
Cheng, Yong
;
Jiang, Xueying
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Chirality
Clausenamide
Dementia
Long-term potentiation
Signaling pathway
Calcium
6-OHDA
6-hydroxyldopamine
ACE
acetylcholinesterase
ACh
acetylcholine
AD
Alzheimer's disease
AUC0–12 h
0–12 h area under curve
APP
amyloid precursor protein
APV
R-2-amino-5-phosphonopentanoate
AUC0−∝
whole area under curve
BBB
blood–brain barrier
BDNF
brain-derived neurotrophic factor
CaM
calmodulin
CaMKII
calmodulin kinase II
ChAT
choline acetyltransferase
CREB
cAMP responding element binding
CHM
Chinese herbal medicine
clau
clausenamide
CL
clearance
Cmax
maximum concentration
CDK-5
cyclin-dependent kinase-5
DM
diabetes mellitus
DAG
diacylglycerol
ER
endoplasmic reticulum
ERK
extracellular signal-regulated kinases
GSK-3
glycogen synthase kinase-3
IP3
inositol triphosphate
LTP
long term potentiation
MWM
Morris water maze
NGF
nerve growth factor
NMDA
N-Methyl-D-aspartate
D
nNOS
neural nitric oxide synthase
PAT
passive avoidance tasks
Pir
piracetam
PLC
phospholipase C
PP1
phosphate 1
PKC
protein kinase C
tmax
time of peak concentration
t1/2α
absorption half-life
t1/2β
elimination half-life
Tau
microtubule-associated proteins
TCM
traditional Chinese medicine
Vd
apparent volume of distribution
VDCC
voltage-dependent calcium channel
Astrocytic Ca2+ waves mediate activation of extrasynaptic NMDA receptors in hippocampal neurons to aggravate brain damage during ischemia
期刊论文
疾病神经生物学实验神经学b辑, 2013
Dong, Qi-ping
;
He, Jing-quan
;
Chai, Zhen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/10
Ischemia
Extrasynaptic NMDA receptor
Astrocytic Ca2+ wave
Gap junction
CALCIUM WAVES
GLUTAMATE RELEASE
CELL-DEATH
IN-VITRO
PROPAGATION
MICE
EXCITOTOXICITY
PLASTICITY
CONTRIBUTE
EPILEPSY
Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca2+-dependent cofilin activation and RhoA inhibition
期刊论文
JOURNAL OF CELL SCIENCE, 2011, 卷号: 124, 期号: 2, 页码: 186-197
Huang, Zhi-hui
;
Wang, Ying
;
Su, Zhi-da
;
Geng, Jian-guo
;
Chen, Yi-zhang
;
Yuan, Xiao-bing
;
He, Cheng
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2012/07/13
Ca2+
Cofilin
Migration
Olfactory ensheathing cells
RhoA
Slit-2
ACTIN-FILAMENT TURNOVER
LIM-KINASE
GROWTH CONE
NEURONAL MIGRATION
SLINGSHOT PHOSPHATASE
AXON GUIDANCE
NEURITE OUTGROWTH
FAMILY GTPASES
SPINAL-CORD
IN-VITRO
Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca2+-dependent cofilin activation and RhoA inhibition
期刊论文
JOURNAL OF CELL SCIENCE, 2011, 卷号: 124, 期号: 2, 页码: 186-197
作者:
Huang, ZH
;
Wang, Y
;
Su, ZD
;
Geng, JG
;
Chen, YZ
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2015/07/22
Ca2+
Cofilin
Migration
Olfactory ensheathing cells
RhoA
Slit-2
ChIP-seq and Functional Analysis of the SOX2 Gene in Colorectal Cancers
期刊论文
2010
Fang, Xuefeng ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI)
;
Yu, Wei ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI)
;
Li, Lisha ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI)
;
Shao, Jiaofang ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI)
;
Zhao, Na ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI)
;
Chen, Qiyun ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI)
;
Lin, Biaoyang ( Zhejiang Univ, Syst Biol Div, Zhejiang California Int Nanosyst Inst ZCNI)
;
Zheng, Shu ( Zhejiang Univ, Affiliated Hosp 2, Key Lab Canc Prevent & Intervent, China Nat)
;
Ye, Zhiyun
;
叶志云
;
Lin, Sheng-Cai
;
林圣彩
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2011/07/12
Src homology 2 domain-containing inositol-5-phosphatase 1 (SITP1) negatively regulates TLR4-mediated LPS response primarily through a phosphatase activity- and PI-3K-independent mechanism
期刊论文
2010, 2010
An, HZ
;
Xu, HM
;
Zhang, MH
;
Zhou, J
;
Feng, T
;
Qian, C
;
Qi, RZ
;
Cao, XT
收藏
  |  
浏览/下载:4/0
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