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Solubilization, purification, and ligand binding characterization of G protein-coupled receptor SMO in native membrane bilayer using styrene maleic acid copolymer
期刊论文
PEERJ, 2022, 卷号: 10
作者:
Zhu, Lina
;
Zhao, Hongxin
;
Wang, Yizhuo
;
Yu, Chuandi
;
Liu, Juanjuan
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/23
GPCR
Dissociation constant
Detergents
Styrene maleic acid copolymer nanodiscs
Smoothened receptors
NMR
PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 7, 页码: 10
作者:
Yang, Jun
;
Wang, Juan
;
Liu, Yuan
;
Zhang, Yu
;
Huang, Wenjing
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/08/17
Dual activation of Hedgehog and Wnt/beta-catenin signaling pathway caused by downregulation of SUFU targeted by miRNA-150 in human gastric cancer
期刊论文
AGING-US, 2021, 卷号: 13, 期号: 7, 页码: 10749-10769
作者:
Peng, Yin
;
Zhang, Xiaojing
;
Lin, Huijuan
;
Deng, Shiqi
;
Qin, Ying
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/12/01
miRNA-150
SUFU
Wnt/beta-catenin
hedgehog
EMT
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:
Liu, Xiaohua
;
Zhang, Yu
;
Li, Yalei
;
Wang, Juan
;
Ding, Huaqian
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
Medulloblastoma
Hedgehog signaling
pathway
Drug resistance
GLI
BRD4
The hedgehog pathway suppresses neuropathogenesis in CD4 T cell-driven inflammation
期刊论文
BRAIN, 2021, 卷号: 144
作者:
Benallegue, Nail
;
Kebir, Hania
;
Kapoor, Richa
;
Crockett, Alexis
;
Li, Cen
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/11/18
sonic hedgehog
neuroinflammation
autoimmunity
experimental autoimmune encephalomyelitis
T cells
SUFU mediates EMT and Wnt/beta-catenin signaling pathway activation promoted by miRNA-324-5p in human gastric cancer
期刊论文
CELL CYCLE, 2020, 页码: 14
作者:
Peng, Yin
;
Zhang, Xiaojing
;
Lin, Huijuan
;
Deng, Shiqi
;
Qin, Ying
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/12/10
miRNA-324-5p
SUFU negative regulator of hedgehog signaling
Wnt/beta-catenin
EMT
USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines
期刊论文
FEBS JOURNAL, 2020, 页码: 18
作者:
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Xiong, Muya
;
Zhu, Mengying
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2020/12/24
colorectal cancer
HDX-MS
inhibitor
USP25
USP28
Vismodegib
Medulloblastoma: Molecular understanding, treatment evolution, and new developments
期刊论文
PHARMACOLOGY & THERAPEUTICS, 2020, 卷号: 210, 页码: 13
作者:
Liu, Xiaohua
;
Ding, Chunyong
;
Tan, Wenfu
;
Zhang, Ao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Medulloblastoma
Pediatric brain tumor
Oncogenic driver gene
Hedgehog pathway inhibitor
Smoothened receptor antagonist
Analysis of Four Types of Leukemia Using Gene Ontology Term and Kyoto Encyclopedia of Genes and Genomes Pathway Enrichment Scores
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2020, 卷号: 23, 期号: 4, 页码: 295-303
作者:
Lu, Jing
;
Zhang, YuHang
;
Wang, ShaoPeng
;
Bi, Yi
;
Huang, Tao
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
Leukemia
protein-drug interactions
GO term
KEGG pathway
enrichment score
mRMR
Quantitative proteomics analysis of the treatment of asthma rats with total flavonoid extract from chamomile
期刊论文
BIOTECHNOLOGY LETTERS, 2020, 卷号: 42, 期号: 6, 页码: 905-916
作者:
Li, Q (Li, Qian)[ 1,2,3 ]
;
Zhao, SJ (Zhao, Shengjun)[ 2 ]
;
Lu, J (Lu, Jun)[ 2 ]
;
Kang, XL (Kang, Xiaolong)[ 2 ]
;
Zhang, G (Zhang, Gang)[ 2 ]
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/05/27
Asthma
Chamomile
Differential expressed proteins
KIF3A
Hedgehog signaling pathway
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