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上海药物研究所 [38]
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Magnetic-optical dual-modality imaging monitoring chemotherapy efficacy of pancreatic ductal adenocarcinoma with a low-dose fibronectin-targeting Gd-based contrast agent
期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2024, 页码: 15
作者:
Zhang, Wenjia
;
Liang, Xiaolong
;
Zhang, Xinyu
;
Tong, Wei
;
Shi, Guangyuan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/07/03
Molecular imaging
Magnetic resonance imaging
Fluorescence molecular imaging
Pancreatic cancer
Fibronectin
Circulating tRNA-Derived Small RNAs as Novel Radiation Biomarkers of Heavy Ion, Proton and X-ray Exposure
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 24, 页码: 15
作者:
Wei, Wenjun
;
Bai, Hao
;
Chen, Yaxiong
;
Zhang, Tongshan
;
Zhang, Yanan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/04/11
tsRNA
serum
biomarkers
radiation exposure
multi-factor models
Estimated Manipulation of Tablets and Capsules to Meet Dose Requirements for Chinese Children: A Cross-Sectional Study
期刊论文
FRONTIERS IN PEDIATRICS, 2021, 卷号: 9
作者:
Zhang, Liwen
;
Hu, Yan
;
Pan, Panpan
;
Hong, Chengtao
;
Fang, Luo
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/01/10
capsule
manipulation
pediatric
tablet
prescription
drug dose
Absorption, distribution, metabolism, and excretion of [C-14]NBP (3-n-butylphthalide) in rats
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 9
作者:
Tian, Junjun
;
Lei, Peng
;
He, Yifei
;
Zhang, Ning
;
Ge, Xinyu
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
3-n-butylphthalide (NBP)
[C-14]NBP
Pharmacokinetics
Tissue distribution
Metabolism
Mass balance
Experimental Study on Fusion Neutron Activation of Metal Materials in EAST
期刊论文
IEEE TRANSACTIONS ON PLASMA SCIENCE, 2021, 卷号: 49
作者:
Zhang, Ruixue
;
Hong, Bing
;
Hu, Liqun
;
Li, Kai
;
Zhong, Guoqiang
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/06/15
Neutrons
Gamma-rays
Radiation effects
Plasmas
Manganese
Detectors
Heating systems
Experimental Advanced Superconducting Tokamak (EAST)
full energy peak efficiency(FEPE)
gamma ray
gamma ray detector
gamma ray dose rate
material activation
neutron activation experiment
plasma discharge
specific activity
Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 2, 页码: 396-409
作者:
Zhang, Yi-fan
;
Liu, Yan-mei
;
Yu, Chen
;
Wang, Ya-ting
;
Zhan, Yan
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/05/24
diabetes
henagliflozin
pharmacodynamics
pharmacokinetics
SGLT-2 inhibitors
A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15, 页码: 2947-2959
作者:
Qian, Hongjie
;
Chen, Qian
;
Lang, Liyu
;
Zou, Yang
;
Pu, Huahua
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/08/17
TPN171H
PDE5 inhibitor
safety
pharmacokinetics
food effect
healthy subjects
Perfluorooctane sulfonate enhances mRNA expression of PPAR gamma and ap2 in human mesenchymal stem cells monitored by long-retained intracellular nanosensor
期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 263, 页码: 1-9
作者:
Gao, Yu
;
Guo, Xixi
;
Wang, Siyu
;
Chen, Fubin
;
Ren, Xiaomin
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/09/14
Intracellular nanosensor
Perfluorooctane sulfonate
Real-time function assessment
Human mesenchymal stem cells
Adipogenic differentiation
基于聚乳酸微球佐剂的乙肝疫苗研究
学位论文
: 中国科学院大学, 2020
作者:
卢婷
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/09/07
聚乳酸微球,双十八烷基二甲基溴化铵,Sting刺激剂,慢性乙肝模型鼠,冻干
Phase I dose-escalation and expansion study of PARP inhibitor, fluzoparib (SHR3162), in patients with advanced solid tumors
期刊论文
CHINESE JOURNAL OF CANCER RESEARCH, 2020, 卷号: 32, 期号: 3, 页码: 370-+
作者:
Li, Huiping
;
Liu, Rongrui
;
Shao, Bin
;
Ran, Ran
;
Song, Guohong
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
Phase I
PARP inhibitor (fluzoparib)
solid tumor
pharmacokinetics
safety
antitumor activity
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