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西安交通大学 [20]
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期刊论文 [18]
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Human ether‑à‑go‑go‑related gene mutation L539fs/47‑hERG leads to cell apoptosis through the endoplasmic reticulum stress pathway.
期刊论文
International journal of molecular medicine, 2019, 卷号: 43, 页码: 1253-1262
作者:
Ma Shuting
;
Zhao Yun
;
Cao Miaomiao
;
Sun Chaofeng
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/19
F463L increases the potential of dofetilide on human ether-a-go-go-related gene (hERG) channels
期刊论文
MICROSCOPY RESEARCH AND TECHNIQUE, 2018, 卷号: 81, 页码: 663-668
作者:
Cheng, Gong
;
Wu, Jine
;
Han, Wenqi
;
Sun, Chaofeng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/19
drug-induced LQTS
Dofetilide
whole-cell patch
mutation
hERG gene
A trafficking-deficient KCNQ1 mutation, T587M, causes a severe phenotype of long QT syndrome by interfering with intracellular hERG transport.
期刊论文
Journal of cardiology, 2018
作者:
Wu Jie
;
Sakaguchi Tomoko
;
Takenaka Kotoe
;
Toyoda Futoshi
;
Tsuji Keiko
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/26
Fluorescence resonance energy transfer
Patch-clamp
hERG
Long QT syndrome
KCNQ1-T587M
A hERG mutation E1039X produced a synergistic lesion on &ITI&ITKs together with KCNQ1-R174C mutation in a LQTS family with three compound mutations
期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:
Wu, Jie
;
Mizusawa, Yuka
;
Ohno, Seiko
;
Ding, Wei-Guang
;
Higaki, Takashi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/26
Increasing Calpain Expression Regulates hERG Mutation L539fs/47 Induced Cardiomyocyte Apoptosis
会议论文
作者:
Ma, Shuting
;
Zhao, Yun
;
Wei, Yuejiao
;
Sun, Chaofeng
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  |  
浏览/下载:12/0
  |  
提交时间:2019/11/26
NS1643 enhances ionic currents in a G604S-WT hERG co-expression system associated with long QT syndrome 2
期刊论文
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2017, 卷号: 44, 页码: 1125-1133
作者:
Huo, JianHua
;
Guo, Xueyan
;
Lu, Qun
;
Qiang, Hua
;
Liu, Ping
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/26
hERG mutation
NS1643
patch-clamp
long QT syndrome
Propofol inhibits hERG K+ channels and enhances the inhibition effects on its mutations in HEK293 cells
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2016, 卷号: 791, 页码: 168-178
作者:
Han, Sheng-Na
;
Jing, Ying
;
Yang, Lin-Lin
;
Zhang, Zhao
;
Zhang, Li-Rong
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Propofol
QT prolongation
Human ether-a-go-go-related gene (hERG)
Protein trafficking
Gene mutation
Association of the hERG mutation with long-QT syndrome type 2, syncope and epilepsy
期刊论文
MOLECULAR MEDICINE REPORTS, 2016, 卷号: 13, 期号: [db:dc_citation_issue], 页码: 2467-2475
作者:
Li, Guoliang
;
Shi, Rui
;
Wu, Jine
;
Han, Wenqi
;
Zhang, Aifeng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/02
human ether-a-go-go-related gene
long-QT syndrome
whole-cell patch-clamp
mutation
trafficking
Pharmacological rescue of hERG currents carried out by G604S and wide type hERG co-expression
期刊论文
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2016, 卷号: 43, 期号: [db:dc_citation_issue], 页码: 851-861
作者:
Huo, Jianhua
;
Zhang, Aifeng
;
Guo, Xueyan
;
Qiang, Hua
;
Liu, Ping
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/02
hERG mutation
patch-clamp
G604S
long QT syndrome
The mutant L539fs/47 has the effect of an incomplete dominant negative inhibition on wild type HERG current in HEK293 cells
期刊论文
Journal of Xi'an Jiaotong University (Medical Sciences), 2016, 卷号: 37
作者:
Lü, Ying
;
Zhang, Jun-Bo
;
Zhang, Ai-Feng
;
Liu, Zhong-Wei
;
Wang, Jun-Kui
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
HEK293 cell
Human ether-a-go-go-related gene (HERG)
Incomplete dominant negative inhibition
Nonsense mutation
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