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科研机构
上海药物研究所 [10]
大连化学物理研究所 [5]
中国农业科学院 [2]
生态环境研究中心 [2]
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期刊论文 [13]
会议论文 [5]
学位论文 [1]
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2021 [1]
2018 [1]
2017 [1]
2016 [4]
2015 [3]
2013 [2]
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物理化学 [5]
biochemica... [2]
chemistry,... [2]
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UPLC-ESI-Q-TOF/MS Based Metabolic Profiling of Protosappanin B in Rat Plasma, Bile, Feces, Urine and Intestinal Bacteria Samples
期刊论文
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 6, 页码: 491-499
作者:
Chen, Wei-Ying
;
Liang, Guang-Yan
;
Zheng, Zuo-Liang
;
Wu, Yun-Shan
;
Xu, Fang-Fang
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/11/04
Protosappanin B
Metabolic pathways
UPLC-TOF-MS
MS
Plasma
Bile
Feces
Urine
Intestinal bacteria sample
Metabolites and Metabolic Pathway Analysis of Brazilin in Rats by UPLC-Q-TOF-MS/MS
期刊论文
Chinese Journal of Experimental Traditional Medical Formulae, 2018, 卷号: 24, 期号: 1, 页码: 67-73
作者:
LIANG Guang-yan
;
WU Yun-shan
;
CHEN Wei-ying
;
LIU Bo
;
GUO De-an
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
brazilin
Sappan Lignum
metabolites
sulfation
glucuronide conjugation
urine
bile
The profiling of the metabolites of hirsutine in rat by ultra-high performance liquid chromatography coupled with linear ion trap Orbitrap mass spectrometry: An improved strategy for the systematic screening and identification of metabolites in multi-samples in vivo
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2017, 卷号: 134, 页码: 149-157
作者:
Wang, Jianwei
;
Qi, Peng
;
Hou, Jinjun
;
Shen, Yao
;
Yang, Min
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Hirsutine
Metabolic profile
Multi-samples
Metabolites systematic screening
Uncaria rhynchophylla
UHPLC/LTQ-Orbitrap-MS
Profiling and identification of metabolites of isorhynchophylline in rats by ultra high performance liquid chromatography and linear ion trap Orbitrap mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1033, 页码: 147-156
作者:
Wang, Jianwei
;
Qi, Peng
;
Hou, Jinjun
;
Shen, Yao
;
Yan, Bingpeng
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Isorhynchophyllin
UHPLC/LTQ-Orbitrap-MS
Metabolic profile
Metabolites
氟调醇的代谢转化机制研究
学位论文
硕士, 北京: 中国科学院研究生院, 2016
作者:
李忠民
收藏
  |  
浏览/下载:137/0
  |  
提交时间:2017/07/12
氟调醇
FTOHs
I相代谢
phase I metabolism
II相代谢
phase II metabolism
代谢动力学
metabolic kinetics
分子对接
molecular docking
Biotransformation of 8:2 fluorotelomer alcohol by recombinant human cytochrome P450s, human liver microsomes and human liver cytosol
期刊论文
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS, 2016, 卷号: 18, 期号: 5, 页码: 538-546
作者:
Li, Zhong-Min
;
Guo, Liang-Hong
;
Ren, Xiao-Min
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2017/03/27
A simple method for quantification of tapentadol in dog plasma by liquid chromatography-tandem mass spectrometry and evaluation of the effects of conjugated metabolites on tapentadol
期刊论文
Acta Pharmaceutica Sinica, 2016, 卷号: 51, 期号: 3, 页码: 434-438
作者:
Liang Ge
;
Lu Youming
;
Dai Xiaojian
;
Qin Minjian
;
Zhong Dafang
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
LC-MS/MS
LC-MS/MS
tapentadol
conjugated metabolite
pharmacokinetics
Metabolism by conjugation appears to confer resistance to paracetamol (acetaminophen) hepatotoxicity in the cynomolgus monkey
期刊论文
XENOBIOTICA, 2015, 卷号: 45, 期号: 3, 页码: 270-277
作者:
Yu, Hong
;
Barrass, Nigel
;
Gales, Sonya
;
Lenz, Eva
;
Parry, Tony
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Cynomolgus monkeys
detoxification by glucuronidation
paracetamol toxicity
Profiling and identification of the metabolites of baicalin and study on their tissue distribution in rats by ultra-high-performance liquid chromatography with linear ion trap-Orbitrap mass spectrometer
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2015, 卷号: 985, 页码: 91-102
作者:
Zhang, Jiayu
;
Cai, Wei
;
Zhou, Yuan
;
Liu, Ying
;
Wu, Xiaodan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/04/17
Baicalin
UPLC-ESI-MS/MS
Metabolic profile
Distribution
Multiple data processing method
Profiling and identification of the metabolites of baicalin and study on their tissue distribution in rats by ultra-high-performance liquid chromatography with linear ion trap-Orbitrap mass spectrometer
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2015, 卷号: 985, 页码: 91-102
作者:
Zhang, Jiayu
;
Cai, Wei
;
Zhou, Yuan
;
Liu, Ying
;
Wu, Xiaodan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/04/23
Baicalin
UPLC-ESI-MS/MS
Metabolic profile
Distribution
Multiple data processing method
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