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Palladium-Catalyzed Tandem Carbonylative Aza-Wacker-Type Cyclization of Nucleophile Tethered Alkene to Access Fused N-Heterocycles
期刊论文
Chinese Journal of Chemistry, 2021, 卷号: 39, 期号: 2, 页码: 317-322
作者:
Shi Lijun
;
Wen Mingshan
;
Li Fuwei
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/11/20
Palladium
Tandem reaction
Carbonylation
Heterocycles
Alkenes
Palladium‐catalyzed tandem carbonylative aza‐Wacker‐type cyclization of nucleophile tethered alkene to access fused N‐heterocycles
期刊论文
Chinese Journal of Chemistry, 2020, 卷号: 39, 期号: 3, 页码: 317
作者:
Lijun Shi
;
Wenming Shan
;
Li FW(李福伟)
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/01/30
Synthesis of Highly Fused Pyrano[2,3-b]pyridines via Rh(III)- Catalyzed C-H Activation and Intramolecular Cascade Annulation under Room Temperature
期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 85, 期号: 10, 页码: 6281-6294
作者:
Han, Xu
;
Gao, Feng
;
Li, Chunpu
;
Fang, Daqing
;
Xie, Xiong
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  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Mn-Catalyzed Dehydrocyanative Transannulation of Heteroarenes and Propargyl Carbonates through C-H Activation: Beyond the Permanent Directing Effects of Pyridines/Pyrimidines
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 卷号: 58, 期号: 15, 页码: 5090-5094
作者:
Xu, Youwei
;
Li, Xingwei
;
Zheng, Guangfan
;
Sun, Jiagiong
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/06/20
allenylation
C-H activation
Diels-Alder reactions
directing groups
Manganese
Gold-catalyzed Rapid Construction of Nitrogen-containing Heterocyclic Compound Library with Scaffold Diversity and Molecular Complexity
期刊论文
ADVANCED SYNTHESIS & CATALYSIS, 2019, 卷号: 361, 期号: 6, 页码: 1419-1440
作者:
Qiao, Jin
;
Jia, Xiuwen
;
Li, Pinyi
;
Liu, Xiaoyan
;
Zhao, Jingwei
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  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
Alkynes
Amines
Cascade reaction
Compound library
Gold
Scaffold diversity
Green and Facile Assembly of Diverse Fused N-Heterocycles Using Gold-Catalyzed Cascade Reactions in Water
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 5, 页码: 30
作者:
Jia, Xiuwen
;
Li, Pinyi
;
Liu, Xiaoyan
;
Lin, Jiafu
;
Chu, Yiwen
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  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
amine nucleophiles
alkynoic acids
cascade reaction
gold catalysis
fused N-heterocycles
Palladium-Catalyzed Propargylic [n+2] Cycloaddition: An Efficient Strategy for Construction of Benzo-Fused Medium-Sized Heterocycles
期刊论文
ADVANCED SYNTHESIS & CATALYSIS, 2019, 卷号: 361, 期号: 4, 页码: 836-841
作者:
Liu, Zhen-Ting
;
Hu, Xiang-Ping
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  |  
浏览/下载:52/0
  |  
提交时间:2019/06/20
A regioselective palladium-catalyzed formal [n+2] cycloaddition of propargylic esters as C-2-synthons with various linker-tethered bisphenols for the construction of medium-sized heterocycles bearing an exocyclic double bond has been developed
The reaction features mild conditions and broad substrate scopes
as well as readily available substrates and catalysts
Under optimal conditions
various medium-sized heterocycles from eight to eleven-membered rings can be afforded in good to excellent yields and regioselectivities with high Z-selectivity for the exocyclic double bond
palladium
medium-sized ring
propargylic ester
bisphenol
cycloaddition
Palladium-catalyzed propargylic [n+2] cycloaddition: an efficient strategy for construction of benzo-fused medium-sized heterocycles
期刊论文
Advanced synthesis & catalysis, 2019, 卷号: 361, 期号: 4, 页码: 836-841
作者:
Liu, Zhen-Ting
;
Hu, Xiang-Ping
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2019/05/08
A regioselective palladium-catalyzed formal [n+2] cycloaddition of propargylic esters as c-2-synthons with various linker-tethered bisphenols for the construction of medium-sized heterocycles bearing an exocyclic double bond has been developed
The reaction features mild conditions and broad substrate scopes
As well as readily available substrates and catalysts
Under optimal conditions
Various medium-sized heterocycles from eight to eleven-membered rings can be afforded in good to excellent yields and regioselectivities with high z-selectivity for the exocyclic double bond
Palladium
Medium-sized ring
Propargylic ester
Bisphenol
Cycloaddition
Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178
作者:
Gao, Feng
;
Liang, Yuru
;
Zhou, Pengfei
;
Cheng, Jiayi
;
Ding, Kuiling
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
Imidazo[4,5-c]pyridin-2-one
Tubulin polymerization
Katanin
Antitumor
Design, synthesis and biological evaluation of novel, orally bioavailable pyrimidine-fused heterocycles as influenza PB2 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162
作者:
Xiong, Jian
;
Wang, Jingjing
;
Hu, Guoping
;
Zhao, Weili
;
Li, Jianqi
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Influenza
Polymerase inhibitor
PB2
Drug design
Metabolic stability
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