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科研机构
厦门大学 [24]
上海药物研究所 [21]
兰州大学 [5]
湖南中医药大学 [5]
南华大学 [4]
北京大学 [4]
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期刊论文 [107]
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浏览/检索结果:
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Hydroxypropyltrimethyl ammonium chloride chitosan activates RAW 264.7 macrophages through the MAPK and JAK-STAT signaling pathways
期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 205, 页码: 401-409
作者:
Yang, Yue
;
Xing, Ronge
;
Liu, Song
;
Qin, Yukun
;
Li, Kecheng
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/05/15
Hydroxypropyltrimethyl ammonium chloride
chitosan
Immunostimulatory activity
ERK
JNK
P38
STAT
Immunostimulatory Effects of Chitooligosaccharides on RAW 264.7 Mouse Macrophages via Regulation of the MAPK and PI3K/Akt Signaling Pathways
期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 1, 页码: 12
作者:
Yang, Yue
;
Xing, Ronge
;
Liu, Song
;
Qin, Yukun
;
Li, Kecheng
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2019/08/28
chitooligosaccharide
immunostimulatory activity
RAW 264
7 cells
mitogen-activated protein kinases (MAPK)
phosphoinositide 3-kinases (PI3K)
Akt
Steroidal alkaloid solanine A from Solanum nigrum Linn. exhibits anti-inflammatory activity in lipopolysaccharide/interferon gamma-activated murine macrophages and animal models of inflammation
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 105, 期号: 2018, 页码: 606-615
作者:
Zhao, Lin
;
Wang, Lun
;
Di, Suo-ni
;
Xu, Qian
;
Ren, Qing-cuo
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/12/24
Solanine A
Solanum nigrum Linn.
Anti-inflammatory activity
NF-kappa B and MAPKs cascades
PI3K/Akt and JAK/STATs signalings
Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 4, 页码: 552-562
作者:
Liu, Feifei
;
Yang, Xiaotong
;
Geng, Meiyu
;
Huang, Min
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Mitogen-activated protein kinases
Extracellular signal-regulated kinase
ERK inhibitor
ERK kinase
Cancer therapy
Drug resistance
Identification and characterization of microRNAs involved in ascidian larval metamorphosis
期刊论文
BMC GENOMICS, 2018, 卷号: 19, 页码: 12
作者:
Zhang, Xiaoming
;
Liu, Xiaozhuo
;
Liu, Chengzhang
;
Wei, Jiankai
;
Yu, Haiyan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2018/05/31
microRNAs
Ciona savignyi
Metamorphosis
Mesenchyme
Signaling pathways
Molecular cloning and characterization of a putative mitogen-activated protein kinase (Erk1/2) gene: Involvement in mantle immunity of Pinctada fucata
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 80, 页码: 63, 70
作者:
Liu, Wenguang
;
Huang, Xiande
;
Xu, Meng
;
Shi, Yu
;
Ou, Zekui
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/08/28
Pinctada fucata
Expression patterns
Mantle immunity
ERK
lncRNAPCAT29 inhibits pulmonary fibrosis via the TGF-1-regulated RASAL1/ERK1/2 signal pathway
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 17, 期号: 6, 页码: 7781-7788
作者:
Liu, Xiaoming
;
Gao, Shanyu
;
Xu, Huile
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
pulmonary fibrosis
long non-coding RNA prostate cancer-associated
transcript 29
inflammation
transforming growth factor-1
microRNA-221
RAS protein activator like 1
extracellular signal-regulated kinases 1/2
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular Immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
Myelin injury in the central nervous system and Alzheimer's disease
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 162-168
作者:
Wang, Sha-Sha
;
Zhang, Zhao
;
Zhu, Tian-Bi
;
Chu, Shi-Feng
;
He, Wen-Bin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/27
OLG
oligodendrocyte
CNS
central nervous system
SC
Schwann cell
PNS
peripheral nervous system
MBP
myelin basic protein
PLP
proteolipid protein
P0/MPZ
myelin protein zero
EAE
experimental allergic encephalomyelitis
MS
multiple sclerosis
CNP
2′ 3′-cyclic nucleotide 3′-phosphodiesterase
MAG
myelin associated glycoprotein
MOG
myelin oligodendrocyte glycoprotein
AD
Alzheimer's disease
OPC
oligodendrocyte precursor cell
NPC
neural progenitor cell
ROS
reactive oxygen species
TNF
tumour necrosis factor
AIF
apoptosis-inducing factor
IFN-γ
interferon gamma
ERK1/2
extracellular signal-regulated kinases-1 and -2
MAPK
mediators of mitogen-activated protein kinase
FGFR1/2
fibroblast growth factor receptors-1 and -2
Dock3
dedicator of cytokinesis 3
PERK
pancreatic endoplasmic reticulum kinase
GEF
guanine nucleotide exchange factor
SIRT2
sirtuin 2
NOD2
Nucleotide-binding oligomerization domain containing protein 2
RIPK2
receptor-interacting serine/threonine kinase 2
Shh
Sonic Hedgehog
NMO
neuromyelitis optica
ADEM
acute disseminated encephalomyelitis
ANHLE
acute necrotizing hemorrhagic leukoencephalitis
CPM
central pontine myelinolysis
Aβ
beta-amyloid
SP
senile plaque
NFT
neurofibrillary tangle
MRI
magnetic resonance imaging
Myelin
Oligodendrocyte
Demyelination
Neurodegenerative diseases
Alzheimer’s disease
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
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